Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Silvia Nerreter"'
Autor:
Umair Munawar, Johanna Theuersbacher, Maximilian J. Steinhardt, Xiang Zhou, Seungbin Han, Silvia Nerreter, Cornelia Vogt, Shilpa Kurian, Thorsten Keller, Ann-Katrin Regensburger, Eva Teufel, Julia Mersi, Max Bittrich, Franziska Seifert, Malik S. Haider, Leo Rasche, Jost Hillenkamp, Hermann Einsele, Daniel Kampik, K. Martin Kortüm, Johannes M. Waldschmidt
Publikováno v:
Haematologica, Vol 109, Iss 11 (2024)
Externí odkaz:
https://doaj.org/article/09c3d7b2071d4832b1033ee4fc16cf6d
Autor:
Umair Munawar, Xiang Zhou, Sabrina Prommersberger, Silvia Nerreter, Cornelia Vogt, Maximilian J. Steinhardt, Marietta Truger, Julia Mersi, Eva Teufel, Seungbin Han, Larissa Haertle, Nicole Banholzer, Patrick Eiring, Sophia Danhof, Miguel Angel Navarro-Aguadero, Adrian Fernandez-Martin, Alejandra Ortiz-Ruiz, Santiago Barrio, Miguel Gallardo, Antonio Valeri, Eva Castellano, Peter Raab, Maximilian Rudert, Claudia Haferlach, Markus Sauer, Michael Hudecek, J. Martinez-Lopez, Johannes Waldschmidt, Hermann Einsele, Leo Rasche, K. Martin Kortüm
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-9 (2023)
Abstract The treatment landscape in multiple myeloma (MM) is shifting from genotoxic drugs to immunotherapies. Monoclonal antibodies, immunoconjugates, T-cell engaging antibodies and CART cells have been incorporated into routine treatment algorithms
Externí odkaz:
https://doaj.org/article/91aba52b6c244a118ef7a4278eff963f
Autor:
Umair Munawar, Johanna Theuersbacher, Maximilian J. Steinhardt, Xiang Zhou, Seungbin Han, Silvia Nerreter, Cornelia Vogt, Shilpa Kurian, Thorsten Keller, Ann-Katrin Regensburger, Eva Teufel, Julia Mersi, Max Bittrich, Franziska Seifert, Malik S. Haider, Leo Rasche, Jost Hillenkamp, Hermann Einsele, Daniel Kampik, K. Martin Kortüm, Johannes M. Waldschmidt
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Belantamab mafodotin (belantamab) is a first-in-class anti-BCMA antibody-drug conjugate approved for the treatment of triple-class refractory multiple myeloma. It provides a unique therapeutic option for patients ineligible for CAR-T and bispecific a
Externí odkaz:
https://doaj.org/article/5b70ffdb59ff4ed5b400827482becc1e
Autor:
Xiang Zhou, Seungbin Han, Nadine Cebulla, Larissa Haertle, Maximilian J. Steinhardt, Daniel Schirmer, Eva Runau, Leon Flamm, Calvin Terhorst, Laura Jähnel, Cornelia Vogt, Silvia Nerreter, Eva Teufel, Emilia Stanojkovska, Julia Mersi, Umair Munawar, Magnus Schindehütte, Robert Blum, Ann-Kristin Reinhold, Oliver Scherf-Clavel, Heike L. Rittner, Mirko Pham, Leo Rasche, Hermann Einsele, Claudia Sommer, K. Martin Kortüm
Publikováno v:
Biomarker Research, Vol 11, Iss 1, Pp 1-4 (2023)
Abstract We analyzed single nucleotide polymorphisms (SNPs) in PKNOX1 (rs2839629) and in the intergenic region between PKNOX1 and CBS (rs915854) by Sanger sequencing in 88 patients with multiple myeloma treated with bortezomib. All patients (n = 13)
Externí odkaz:
https://doaj.org/article/e043da7190114504a5058138355ee591
Autor:
Xiang Zhou, Benedict Engel, Annika Hofmann, Cornelia Vogt, Silvia Nerreter, Eva Teufel, Emilia Stanojkovska, Marietta Truger, Philipp Weis, Xianghui Xiao, Florian Eisele, Christine Riedhammer, Maximilian Johannes Steinhardt, Umair Munawar, Seungbin Han, Larissa Haertle, Claudia Haferlach, Hermann Einsele, K Martin Kortum, Leo Rasche
Publikováno v:
HemaSphere, Vol 7, p e7047130 (2023)
Externí odkaz:
https://doaj.org/article/a2a970d4467542f7911df1292bd47b0b
Autor:
Xiang Zhou, Andrej Besse, Jessica Peter, Maximilian Johannes Steinhardt, Cornelia Vogt, Silvia Nerreter, Eva Teufel, Emilia Stanojkovska, Xianghui Xiao, Hannah Hornburger, Larissa Haertle, Max Mendez Lopez, Umair Munawar, Angela Riedel, Seungbin Han, Elmer Maurits, Herman S. Overkleeft, Bogdan Florea, Hermann Einsele, K. Martin Kortüm, Christoph Driessen, Lenka Besse, Leo Rasche
Publikováno v:
Haematologica, Vol 108, Iss 6 (2023)
Optimal carfilzomib dosing is a matter of debate. We analyzed the inhibition profiles of proteolytic proteasome subunits β5, β2 and β1 after low-dose (20/27 mg/m2) versus high-dose (≥36 mg/m2) carfilzomib in 103 pairs of peripheral blood mononuc
Externí odkaz:
https://doaj.org/article/145781d6796c4523aa127a2cf8216c97
Autor:
Larissa Haertle, Santiago Barrio, Umair Munawar, Seungbin Han, Xiang Zhou, Michal Simicek, Cornelia Vogt, Marietta Truger, Rafael Alonso Fernandez, Maximilian Steinhardt, Julia Weingart, Renata Snaurova, Silvia Nerreter, Eva Teufel, Andoni Garitano-Trojaola, Matteo Da Viá, Yanira Ruiz-Heredia, Andreas Rosenwald, Niccolò Bolli, Roman Hajek, Peter Raab, Marc S. Raab, Niels Weinhold, Claudia Haferlach, Thomas Haaf, Joaquin Martinez-Lopez, Hermann Einsele, Leo Rasche, K. Martin Kortüm
Publikováno v:
Clinical Cancer Research. 29:279-288
Purpose: Proteasome inhibitors (PI) are the backbone of various treatment regimens in multiple myeloma. We recently described the first in-patient point mutations affecting the 20S subunit PSMB5 underlying PI resistance. Notably, in vivo, the inciden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5c551249727cb68c920952c59b7a171
https://doi.org/10.1158/1078-0432.ccr-22-1161
https://doi.org/10.1158/1078-0432.ccr-22-1161
Autor:
K. Martin Kortüm, Leo Rasche, Hermann Einsele, Joaquin Martinez-Lopez, Thomas Haaf, Claudia Haferlach, Niels Weinhold, Marc S. Raab, Peter Raab, Roman Hajek, Niccolò Bolli, Andreas Rosenwald, Yanira Ruiz-Heredia, Matteo Da Viá, Andoni Garitano-Trojaola, Eva Teufel, Silvia Nerreter, Renata Snaurova, Julia Weingart, Maximilian Steinhardt, Rafael Alonso Fernandez, Marietta Truger, Cornelia Vogt, Michal Simicek, Xiang Zhou, Seungbin Han, Umair Munawar, Santiago Barrio, Larissa Haertle
Genetic variants in the Würzburg dataset.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c5edc14621c67395b1d356017f6da88
https://doi.org/10.1158/1078-0432.22489568.v1
https://doi.org/10.1158/1078-0432.22489568.v1
Autor:
K. Martin Kortüm, Leo Rasche, Hermann Einsele, Joaquin Martinez-Lopez, Thomas Haaf, Claudia Haferlach, Niels Weinhold, Marc S. Raab, Peter Raab, Roman Hajek, Niccolò Bolli, Andreas Rosenwald, Yanira Ruiz-Heredia, Matteo Da Viá, Andoni Garitano-Trojaola, Eva Teufel, Silvia Nerreter, Renata Snaurova, Julia Weingart, Maximilian Steinhardt, Rafael Alonso Fernandez, Marietta Truger, Cornelia Vogt, Michal Simicek, Xiang Zhou, Seungbin Han, Umair Munawar, Santiago Barrio, Larissa Haertle
Primers used for luciferase reporter assay.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94ab1f5ae553627660ff249d55fff161
https://doi.org/10.1158/1078-0432.22489562
https://doi.org/10.1158/1078-0432.22489562
Autor:
K. Martin Kortüm, Leo Rasche, Hermann Einsele, Joaquin Martinez-Lopez, Thomas Haaf, Claudia Haferlach, Niels Weinhold, Marc S. Raab, Peter Raab, Roman Hajek, Niccolò Bolli, Andreas Rosenwald, Yanira Ruiz-Heredia, Matteo Da Viá, Andoni Garitano-Trojaola, Eva Teufel, Silvia Nerreter, Renata Snaurova, Julia Weingart, Maximilian Steinhardt, Rafael Alonso Fernandez, Marietta Truger, Cornelia Vogt, Michal Simicek, Xiang Zhou, Seungbin Han, Umair Munawar, Santiago Barrio, Larissa Haertle
Cell survival of DNMTi pretreated KMS11 cells under BTZ exposure. AlamarBlue assay after 72 hours of incubation with varying concentrations of BTZ (0.5 nM to 4 nM) on DNMTi pretreated cells (48 h 500 nM Aza, 72 h 100 nM Dec) and PI naïve KMS11. No r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2efe67e0f03f46032ca6192050fc18da
https://doi.org/10.1158/1078-0432.22489571.v1
https://doi.org/10.1158/1078-0432.22489571.v1