Výsledky vyhledávání - "Silvia Michelagnoli"

Elevated triglycerides and low HDL cholesterol in transgenic mice expressing human apolipoprotein A-IMilano

Autor: Lori J. Stoltzfus, Giulia Chiesa, John K. Bielicki, Cesare R. Sirtori, Edward M. Rubin, M Santi, Guido Franceschini, Trudy M. Forte, Silvia Michelagnoli

Publikováno v: Atherosclerosis. 136:139-146

In general, plasma concentrations of high density lipoproteins (HDL) are inversely related to the incidence of coronary artery disease. One exception to this trend is individuals with apolipoprotein A-I Milano (apo A-I M ), a molecular variant of apo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52c7d15d100743b8728628af2c7e74cd
https://doi.org/10.1016/s0021-9150(97)00195-0

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Isoelectric focusing and immunoblotting of the platelet membrane glycoprotein complex IIb. IIIA following urea solubilization

Autor: Cesare R. Sirtori, Elisabetha Gianazza, Michela Cassinotti, Roberta Frattini, Silvia Michelagnoli

Publikováno v: Electrophoresis. 13:781-784

Effective solubilization of the major platelet membrane component, the glycoprotein IIb. IIIa complex, can be achieved with 8 M urea. By avoiding nonionic detergents in the separation medium it is possible to obtain clear immunoblot patterns without

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e76048db046e4280ccf526dbbf2844d3
https://doi.org/10.1002/elps.11501301170

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Increased affinity of LDL for their receptors after acipimox treatment in hypertriglyceridemia

Autor: Silvia Michelagnoli, Remo Fumagalli, Cesare R. Sirtori, C. Torre, Stefano Bellosta, F. Bernini, Guido Franceschini, V. Vaccarino, Franco Pazzucconi

Publikováno v: European Journal of Clinical Pharmacology. 40:S45-S48

The regulation of cellular LDL metabolism by hypertriglyceridemic LDL was tested before and after treatment with acipimox, a nicotinic acid derivative, in 11 type IV hyperlipidemic patients. Large, less dense LDL particles were found in plasma after

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::004392818f4017b7a0398b0ea5d8e665
https://doi.org/10.1007/bf01409408

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Lipoprotein changes and increased affinity of LDL for their receptors after acipimox treatment in hypertriglyceridemia

Autor: Stefano Bellosta, F. Bernini, Remo Fumagalli, Cesare R. Sirtori, Silvia Michelagnoli, V. Vaccarino, Guido Franceschini

Publikováno v: Atherosclerosis. 81:41-49

Modifications in plasma low and high density lipoprotein (LDL and HDL) subfraction distribution, as well as the regulation of cellular LDL metabolism by hypertriglyceridemic LDL were tested before and after treatment with acipimox, a nicotinic acid d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::211984bdd1e018167807bb38c4be1965
https://doi.org/10.1016/0021-9150(90)90057-p

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Effect of gemfibrozil treatment in hypercholesterolemia on low density lipoprotein (LDL) subclass distribution and LDL-cell interaction

Autor: Franco Pazzucconi, Maria Rosa Lovati, Giuseppe Vecchio, Cesare R. Sirtori, Cristina Manzoni, Guido Franceschini, Silvia Michelagnoli, Gemma Gianfranceschi

Publikováno v: Atherosclerosis. 114(1)

Gemfibrozil, a widely used fibric acid derivative, corrects hypercholesterolemia in a non-negligible fraction of patients. To investigate the mechanism of the cholesterol-lowering activity of fibric acids, a study was performed in 12 type IIa hyperli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::849dbd2a9dc74d69a462ca745b72fc48
https://pubmed.ncbi.nlm.nih.gov/7605377

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Glycosylation pattern of platelet glycoprotein IIb and IIIa in type IIa hypercholesterolemia

Autor: Paola Coari, Damiano Baldassarre, Silvia Michelagnoli, Elisabetta Gianazza, Cesare R. Sirtori

Publikováno v: Atherosclerosis. 107(2)

The microheterogeneity and polymorphism of platelet membrane glycoproteins IIb and IIIa from hypercholesterolemic type IIA patients and from normolipidemic controls were compared by isoelectric focusing followed by immunological detection. Their size

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::399610f69eb959146bb3585716a63239
https://pubmed.ncbi.nlm.nih.gov/7980696

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Plasma triglycerides and lipoprotein(a): inverse relationship in a hyperlipidemic Italian population

Autor: Gemma Gianfranceschi, Silvia Michelagnoli, Cesare R. Sirtori, JoséP. Werba, Guido Franceschini, O. Safa

Publikováno v: Atherosclerosis. 101(2)

The relationship between plasma lipoprotein(a) (Lp(a)) levels and other clinical/biochemical variables was investigated in 1200 consecutive hyperlipidemic patients. Plasma Lp(a) concentrations were measured by a sandwich-ELISA method, while the patie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d38ebda143ab47d292388874bd97140
https://pubmed.ncbi.nlm.nih.gov/8379965

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Mechanisms of high-density lipoprotein reduction after probucol treatment: changes in plasma cholesterol esterification/transfer and lipase activities

Autor: Cesare R. Sirotori, Gemma Gianfranceschi, Silvia Michelagnoli, Giulia Chiesa, Guido Franceschini, Michela Cassinotti, Franco Pazzucconi, JoséP. Werba

Publikováno v: Metabolism: clinical and experimental. 42(2)

Probucol treatment results in a significant reduction of plasma high-density lipoprotein (HDL) levels. Since the remodeling of HDL within the plasma compartment is a crucial determinant of HDL levels, the activities of several factors participating i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e523ddb94abcd2de2b6308b11e0fbf1
https://pubmed.ncbi.nlm.nih.gov/8474321

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