Zobrazeno 1 - 10
of 326
pro vyhledávání: '"Silvia Marin"'
Autor:
Joan Serrano-Marín, Silvia Marin, David Bernal-Casas, Alejandro Lillo, Marc González-Subías, Gemma Navarro, Marta Cascante, Juan Sánchez-Navés, Rafael Franco
Publikováno v:
Fluids and Barriers of the CNS, Vol 20, Iss 1, Pp 1-13 (2023)
Abstract Background The lack of accessible and informative biomarkers results in a delayed diagnosis of Parkinson’s disease (PD), whose symptoms appear when a significant number of dopaminergic neurons have already disappeared. The retina, a histor
Externí odkaz:
https://doaj.org/article/769e14cb8b1047628b6f5e8952cce789
Autor:
Cristina Garcia-Beltran, Rita Malpique, Marianne S. Andersen, Firdevs Bas, Judit Bassols, Feyza Darendeliler, Marta Díaz, Barbara Dieris, Flaminia Fanelli, Elke Fröhlich-Reiterer, Alessandra Gambineri, Dorte Glintborg, Abel López-Bermejo, Christopher Mann, Silvia Marin, Barbara Obermayer-Pietsch, Rønnaug Ødegård, Pernille Ravn, Thomas Reinehr, Matteo Renzulli, Cristina Salvador, Viola Singer, Eszter Vanky, Juan Vicente Torres, Melek Yildiz, Francis de Zegher, Lourdes Ibáñez
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-25 (2023)
Abstract Background Polycystic ovary syndrome (PCOS) is the most prevalent, chronic endocrine-metabolic disorder of adolescents and young women (AYAs), affecting 5–10% of AYAs worldwide. There is no approved pharmacological therapy for PCOS. Standa
Externí odkaz:
https://doaj.org/article/cd01e82c8557468c8c62a5200d948371
Autor:
Silvia Marin Barutcieff
Publikováno v:
Acta Historiae Artis Slovenica, Vol 28, Iss 2 (2023)
The paper examines how three residential buildings, edified in Romania in medieval and early modern times by the members of the Golescu family, were repurposed during the 20th and 21st centuries, that is, before, during and after the Romanian communi
Externí odkaz:
https://doaj.org/article/75e2ad1e7e6246f2902a58a33be7442e
Autor:
Adrián Povo-Retana, Marco Fariñas, Rodrigo Landauro-Vera, Marina Mojena, Carlota Alvarez-Lucena, Miguel A. Fernández-Moreno, Antonio Castrillo, Juan Vladimir de la Rosa Medina, Sergio Sánchez-García, Carles Foguet, Francesc Mas, Silvia Marin, Marta Cascante, Lisardo Boscá
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
In recent years, the central role of cell bioenergetics in regulating immune cell function and fate has been recognized, giving rise to the interest in immunometabolism, an area of research focused on the interaction between metabolic regulation and
Externí odkaz:
https://doaj.org/article/8c93cd93dcf841ecb1190e4b14b667a4
Autor:
Ayşegül Erdem, Silvia Marin, Diego A. Pereira-Martins, Marjan Geugien, Alan Cunningham, Maurien G. Pruis, Isabel Weinhäuser, Albert Gerding, Barbara M. Bakker, Albertus T. J. Wierenga, Eduardo M. Rego, Gerwin Huls, Marta Cascante, Jan Jacob Schuringa
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Inhibition of specific metabolic pathways often drives metabolic adaptation. Here, the authors show that FLT3-ITD + acute myeloid leukemia cells are OXPHOS-driven, and inhibition of complex II activity results in increased lactate influx to drive res
Externí odkaz:
https://doaj.org/article/c6190c32ad6545bcbde3640dce0f4ff7
Autor:
Ayşegül Erdem, Silvia Marin, Diego A. Pereira-Martins, Roldán Cortés, Alan Cunningham, Maurien G. Pruis, Bauke de Boer, Fiona A. J. van den Heuvel, Marjan Geugien, Albertus T. J. Wierenga, Annet Z. Brouwers-Vos, Eduardo M. Rego, Gerwin Huls, Marta Cascante, Jan Jacob Schuringa
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Acute myeloid leukemia (AML) is genetically a very heterogeneous disease. Here, Erdem et al. uncover heterogeneity in the metabolic landscape of AML and identify Pyruvate dehydrogenase kinase 1 (PDK1) as a targetable determinant of different metaboli
Externí odkaz:
https://doaj.org/article/0f8fe7450b4e4f25a3960cce038a7ad3
Autor:
Alejandro Lillo, Silvia Marin, Joan Serrano-Marín, Nicolas Binetti, Gemma Navarro, Marta Cascante, Juan Sánchez-Navés, Rafael Franco
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
The composition of the aqueous humor of patients with glaucoma is relevant to understand the underlying causes of the pathology. Information on the concentration of metabolites and small molecules in the aqueous humor of healthy subjects is limited.
Externí odkaz:
https://doaj.org/article/fb804306dada4773bb145e8ebef4fcaa
Autor:
Effrosyni Karakitsou, Carles Foguet, Miriam G. Contreras Mostazo, Nina Kurrle, Frank Schnütgen, Martin Michaelis, Jindrich Cinatl, Silvia Marin, Marta Cascante
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 4059-4066 (2021)
The development of resistance to chemotherapeutic agents, such as Doxorubicin (DOX) and cytarabine (AraC), is one of the greatest challenges to the successful treatment of Acute Myeloid Leukemia (AML). Such acquisition is often underlined by a metabo
Externí odkaz:
https://doaj.org/article/83a4b20897b144cfa36a752f3903e5b0
Autor:
Alejandro Lillo, Silvia Marin, Joan Serrano-Marín, David Bernal-Casas, Nicolas Binetti, Gemma Navarro, Marta Cascante, Juan Sánchez-Navés, Rafael Franco
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 12752 (2022)
The composition of the aqueous humor of patients with type 2 diabetes is relevant to understanding the underlying causes of eye-related comorbidities. Information on the composition of aqueous humor in healthy subjects is limited due to the lack of a
Externí odkaz:
https://doaj.org/article/86d4457cae0e4073bc95045ea1cc1686
Autor:
Silvia Marin Barutcieff
Publikováno v:
Łódzkie Studia Etnograficzne, Vol 58, Iss 0, Pp 195-216 (2019)
This paper aims to examine the context in which an iconographic topic, namely, the visual representations of Saint Christopher, was disseminated from the south to the north of the Carpathian Mountains, in the second half of the 18th century and the b
Externí odkaz:
https://doaj.org/article/ecc2b8bae63c4130b81f6d8b98abd7f5