Výsledky vyhledávání - "Silvia Marchetti"

Efficacy of the additional use of subgingival air-polishing with erythritol powder in the treatment of periodontitis patients: a randomized controlled clinical trial. Part II: effect on sub-gingival microbiome

Autor: Magda Mensi, Elisabetta Caselli, Maria D’Accolti, Irene Soffritti, Roberto Farina, Eleonora Scotti, Maria Elena Guarnelli, Chiara Fabbri, Gianluca Garzetti, Silvia Marchetti, Annamaria Sordillo, Leonardo Trombelli

Publikováno v: Clinical oral investigations.

Objectives To date, scarce evidence exists around the application of subgingival air-polishing during treatment of severe periodontitis. The aim of this study was to evaluate the effect on the health-related and periodontitis-related subgingival micr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3280a3361f817298ca91440f392bfdd
https://pubmed.ncbi.nlm.nih.gov/36538094

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Correlation of metabolic information on FDG-PET with tissue expression of immune markers in patients with non-small cell lung cancer (NSCLC) who are candidates for upfront surgery

Autor: Laura Olivari, Federica Marchesi, Marco Alloisio, Nina Cortese, Dorina Qehajaj, Armando Santoro, Daniela Pistillo, Paola Allavena, Giovanni Francesco Castino, Arturo Chiti, Luca Toschi, Egesta Lopci, Massimo Roncalli, Fabio Grizzi, Daoud Rahal, Silvia Marchetti

Publikováno v: European Journal of Nuclear Medicine and Molecular Imaging. 43:1954-1961

Eliciting antitumor T-cell response by targeting the PD-1/PD-L1 axis with checkpoint inhibitors has emerged as a novel therapeutic strategy in non-small cell lung cancer (NSCLC). The identification of predictors for sensitivity or resistance to these

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66a8f03852a90521ead3872bccdb326d
https://doi.org/10.1007/s00259-016-3425-2

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Abstract 5720: MicroRNA deregulation of the serine synthesis pathway controls intrinsic and non-cell autonomous mechanism of resistance to Regorafenib in metastatic colorectal cancer (mCRC)

Autor: Ruwaida Begum, Khurum Khan, Rodolfo Passalacqua, Marta Schirripa, George Vlachogiannis, Silvia Marchetti, David Cunningham, Somaieh Hedayat, Andrea Lampis, Nicola Valeri, Matteo Fassan, Michele Ghidini, Fotios Loupakis

Publikováno v: Cancer Research. 80:5720-5720

Background: MicroRNAs (miRs) are small non-coding RNAs involved in cell homeostasis. miR dysregulation has been linked with activation of oncogenic pathways, cancer progression and clinical outcome in mCRC. Chemo-refractory mCRC patients are often tr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::28d7768495b44c7a4e221ef51be9a77c
https://doi.org/10.1158/1538-7445.am2020-5720

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Checkpoint inhibitors: 'raising the bar' also in brain metastases from non-small-cell lung cancer?

Autor: Sabrina Rossi, Armando Santoro, Luca Toschi, Giovanna Finocchiaro, Silvia Marchetti

Publikováno v: Immunotherapy. 10(5)

Despite efforts, brain metastases (BM) remain a critical issue in the management of patients affected by non-small-cell lung cancer (NSCLC). To date, radiotherapy is still considered the gold standard treatment; on the other hand, systemic chemothera

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eed15b0cc461016d4ea5f349f84f169
https://pubmed.ncbi.nlm.nih.gov/29473467

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Efficacy of a film-forming medical device containing sunscreen (50+) and piroxicam 0.8% in actinic keratosis and field cancerization: a multicenter, assessor-blinded, 3 month trial

Autor: Elena Campione, Giovanna Tilotta, Virginia Garofalo, Silvia Lovati, Silvia Marchetti, Laura Diluvio, Massimo Milani, Giuseppe Scarcella, Luca Bianchi, Valentina Caputo, Giuseppe Pistone, Chiara Galloni, Paolo Sergio Pavone, Mario Puviani

Publikováno v: Current medical research and opinion. 33(7)

Sunscreen protection in subjects with actinic keratosis (AK) is highly recommended to prevent clinical evolution of this in situ skin cancer condition. Use of topical anti-cyclooxygenase drugs such as diclofenac and piroxicam reduces the number of le

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf377f67eac26ab66f5ed38e713234ee
https://pubmed.ncbi.nlm.nih.gov/28358282

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Circulating miR-652-3p as a biomarker of drug resistance in metastatic colorectal cancer patients

Autor: Matteo Fassan, Fotios Loupakis, Khurum Khan, Silvia Marchetti, George Vlachogiannis, Nicola Valeri, Ruwaida Begum, Andrea Lampis, David Cunningham, Somaieh Hedayat, Marta Schirripa

Publikováno v: Annals of Oncology. 30:vii4

Background MicroRNAs (miRs) are small non-coding RNAs involved in cell homeostasis, carcinogenesis and control multiple oncogenic pathways. Numerous miRs deregulation is associated with clinical outcome. Chemo-refractory metastatic CRC (mCRC) patient

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d448ff221498fe5f324ccaee615eda9b
https://doi.org/10.1093/annonc/mdz413.015

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Abstract LB-305: Circulating miR-652-3p as a biomarker of resistance to regorafenib in metastatic colorectal cancer patients

Autor: Somaieh Hedayat, Khurum Khan, David Cunningham, George Vlachogiannis, Andrea Lampis, Silvia Marchetti, Matteo Fassan, Ruwaida Begum, Marta Schirripa, Fotios Fotios Loupakis, Nicola Valeri

Publikováno v: Cancer Research. 79:LB-305

MicroRNAs (miRs) are small non-coding RNAs involved in cell homeostasis and carcinogenesis and control multiple oncogenic pathways. Numerous miRs are aberrantly expressed in colorectal cancer (CRC) and their deregulation is associated with clinical o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::615ecb22a7fb71fcfdba1d2ebb8778f6
https://doi.org/10.1158/1538-7445.am2019-lb-305

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Efficacy of trabectedin in advanced soft tissue sarcoma: beyond lipo- and leiomyosarcoma [Corrigendum]

Autor: Fabio Romano Lutman, Luca Balzarini, Rita De Sanctis, Armando Santoro, Alexia Bertuzzi, Stefano Bastoni, Vittorio Quagliuolo, Andrea Marrari, Primo Andrea Daolio, Silvia Marchetti, Chiara Mussi

Publikováno v: Drug Design, Development and Therapy

Trabectedin is effective in leiomyosarcoma and liposarcoma, especially the myxoid variant, related to the presence of the FUS-CHOP transcript. We evaluated the efficacy of trabectedin in specific subgroups of patients with soft tissue sarcomas (STS).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6c268cb52217e34ce4ee3b8c4491d1a
https://www.dovepress.com/corrigendum-efficacy-of-trabectedin-in-advanced-soft-tissue-sarco-peer-reviewed-article-DDDT

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PO-472 MicroRNA as biomarkers of resistance to regorafenib in metastatic colorectal cancer patient

Autor: George Vlachogiannis, Ruwaida Begum, F. Loupakis, David Cunningham, Somaieh Hedayat, M. Schirripa, Nicola Valeri, Silvia Marchetti, Matteo Fassan, Khurum Khan

Publikováno v: ESMO Open. 3:A415

Introduction Regorafenib demonstrated efficacy in pre-treated metastatic colorectal cancer (mCRC) patients. Limited clinical benefit in unselected patient populations highlights the unmet need for better patient selection and identification of mechan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::53bccc5d2e2ba2e0c52eab89d55ff5db
https://doi.org/10.1136/esmoopen-2018-eacr25.977

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