Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Silvia Limoncella"'
Autor:
Livio Casarini, Clara Lazzaretti, Elia Paradiso, Silvia Limoncella, Laura Riccetti, Samantha Sperduti, Beatrice Melli, Serena Marcozzi, Claudia Anzivino, Niamh S. Sayers, Jakub Czapinski, Giulia Brigante, Francesco Potì, Antonio La Marca, Francesco De Pascali, Eric Reiter, Angela Falbo, Jessica Daolio, Maria Teresa Villani, Monica Lispi, Giovanna Orlando, Francesca G. Klinger, Francesca Fanelli, Adolfo Rivero-Müller, Aylin C. Hanyaloglu, Manuela Simoni
Publikováno v:
iScience, Vol 23, Iss 12, Pp 101812- (2020)
Summary: Classically, follicle-stimulating hormone receptor (FSHR)-driven cAMP-mediated signaling boosts human ovarian follicle growth and oocyte maturation. However, contradicting in vitro data suggest a different view on physiological significance
Externí odkaz:
https://doaj.org/article/cabed82ba6b444c2afda83fbfa6c92c3
Autor:
Laura Riccetti, Samantha Sperduti, Clara Lazzaretti, Danièle Klett, Francesco De Pascali, Elia Paradiso, Silvia Limoncella, Francesco Potì, Simonetta Tagliavini, Tommaso Trenti, Eugenio Galano, Angelo Palmese, Abhijeet Satwekar, Jessica Daolio, Alessia Nicoli, Maria Teresa Villani, Lorenzo Aguzzoli, Eric Reiter, Manuela Simoni, Livio Casarini
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
Recombinant follicle-stimulating hormone (FSH) (follitropin alfa) and biosimilar preparations are available for clinical use. They have specific FSH activity and a unique glycosylation profile dependent on source cells. The aim of the study is to com
Externí odkaz:
https://doaj.org/article/d4b1c3b28da940e486f506297958f941
Autor:
Samantha Sperduti, Silvia Limoncella, Clara Lazzaretti, Elia Paradiso, Laura Riccetti, Sara Turchi, Ilaria Ferrigno, Jessika Bertacchini, Carla Palumbo, Francesco Potì, Salvatore Longobardi, Robert P. Millar, Manuela Simoni, Claire L. Newton, Livio Casarini
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 22, p 5548 (2019)
Commercial gonadotropin-releasing hormone (GnRH) antagonists differ by 1−2 amino acids and are used to inhibit gonadotropin production during assisted reproduction technologies (ART). In this study, potencies of three GnRH antagonists, Cetrorelix,
Externí odkaz:
https://doaj.org/article/76e6bbc3853545dc89f49aead81c58b5
LH increases the response to FSH in granulosa-lutein cells from sub/poor-responder patients in vitro
Autor:
Samantha Sperduti, Elia Paradiso, Claudia Anzivino, Clara Lazzaretti, Silvia Limoncella, Sara D’Alessandro, Neena Roy, Francesca Reggianini, Tommaso Ferrari, Beatrice Melli, Giovanni Battista La Sala, Alessia Nicoli, Jessica Daolio, Maria Teresa Villani, Simonetta Tagliavini, Tommaso Trenti, Francesco Potì, Reinhild Sandhowe, Chiara Centonze, Monica Lispi, Manuela Simoni, Livio Casarini
Publikováno v:
Human Reproduction. 38:103-112
STUDY QUESTION Does LH addition to FSH in vitro recover the human primary granulosa lutein cell (hGLC) sub/poor-response? SUMMARY ANSWER A picomolar concentration of LH may recover the FSH-induced cAMP and progesterone production of hGLC from sub/poo
Autor:
Flaminia Fanelli, Matteo Magagnoli, Marco Mezzullo, Monica Lispi, Silvia Limoncella, Alessia Tommasini, Carla Pelusi, Daniele Santi, Manuela Simoni, Uberto Pagotto, Livio Casarini
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 229:106270
The canonical androgen synthesis in Leydig cells involves Delta 5 and Delta 4 steroids. Besides, the backdoor pathway, eompassing 5 alpha and 5 alpha,3 alpha steroids, is gaining interest in fetal and adult pathophysiology. Moreover, the role of andr
Autor:
Matteo Magagnoli, Marco Mezzullo, Silvia Limoncella, Alessia Tommasini, Daniele Santi, Carla Pelusi, Manuela Simoni, Uberto Pagotto, Livio Casarini, Flaminia Fanelli
Publikováno v:
Endocrine Abstracts.
Autor:
Salvatore Pacifico, Federica Barbagallo, Marco Sola, Simonetta Tagliavini, Remo Guerrini, Livio Casarini, Silvia Limoncella, Laura Riccetti, Clara Lazzaretti, Giulia Di Rocco, Tommaso Trenti, Manuela Simoni
Publikováno v:
Biochemistry. 58:799-808
Forster resonance energy transfer (FRET)-based biosensors have been recently applied to the study of biological pathways. In this study, a new biosensor was validated for the first time in live HEK293 and steroidogenic MLTC-1 cell lines for studying
Autor:
Silvia Limoncella, Clara Lazzaretti, Elia Paradiso, Sara D'Alessandro, Federica Barbagallo, Salvatore Pacifico, Remo Guerrini, Simonetta Tagliavini, Tommaso Trenti, Daniele Santi, Manuela Simoni, Marco Sola, Giulia Di Rocco, Livio Casarini
Publikováno v:
Molecular and Cellular Endocrinology. 542:111527
Type 5 phosphodiesterase (PDE5) blockade by inhibitors (PDE5i) results in intracellular cyclic guanosine monophosphate (cGMP) increase and smooth muscle relaxation and are used for the treatment of men erectile dysfunction. Although they have high sp
Autor:
Serena Marcozzi, Elia Paradiso, Silvia Limoncella, Giulia Brigante, Livio Casarini, Aylin C. Hanyaloglu, Clara Lazzaretti, Claudia Anzivino, Maria Teresa Villani, Niamh S. Sayers, Laura Riccetti, Francesco Potì, Adolfo Rivero-Müller, Samantha Sperduti, Beatrice Melli, Antonio La Marca, Francesca Gioia Klinger, Jakub Czapinski, Manuela Simoni, Francesca Fanelli
Publikováno v:
Journal of the Endocrine Society
Mechanisms regulating the selection of antral ovarian follicles are poorly understood and supposed to rely on low estrogen levels, decline of follicle-stimulating hormone (FSH) levels and receptor (FSHR) expression. These concepts are challenged in v
Autor:
Francesca Fanelli, Francesco De Pascali, Manuela Simoni, Monica Lispi, Maria Teresa Villani, Silvia Limoncella, Aylin C. Hanyaloglu, Serena Marcozzi, Livio Casarini, Jessica Daolio, Clara Lazzaretti, Laura Riccetti, Elia Paradiso, Francesca Gioia Klinger, Angela Falbo, Giulia Brigante, Niamh S. Sayers, Francesco Potì, Claudia Anzivino, Giovanna Orlando, Jakub Czapinski, Eric Reiter, Adolfo Rivero-Müller, Beatrice Melli, Samantha Sperduti, Antonio La Marca
Classically, follicle stimulating hormone receptor (FSHR) driven cAMP-mediated signaling boosts human ovarian follicle growth and would be essential for oocyte maturation. However, contradicting in vitro suggest a different view on physiological and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1003d56f4173ecf781d9536d85a3789