Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Silvia Lemma"'
Autor:
Daniele Pirone, Daniele Sirico, Lisa Miccio, Vittorio Bianco, Martina Mugnano, Danila del Giudice, Gianandrea Pasquinelli, Sabrina Valente, Silvia Lemma, Luisa Iommarini, Ivana Kurelac, Pasquale Memmolo, Pietro Ferraro
Publikováno v:
Opto-Electronic Advances, Vol 6, Iss 1, Pp 1-16 (2023)
The most recent discoveries in the biochemical field are highlighting the increasingly important role of lipid droplets (LDs) in several regulatory mechanisms in living cells. LDs are dynamic organelles and therefore their complete characterization i
Externí odkaz:
https://doaj.org/article/76a1de2d0ca34fdf9d2039e019ebf9c0
Autor:
Monica De Luise, Manuela Sollazzo, Eleonora Lama, Camelia Alexandra Coadă, Licia Bressi, Maria Iorio, Beatrice Cavina, Luigi D’Angelo, Sara Milioni, Lorena Marchio, Stefano Miglietta, Sara Coluccelli, Greta Tedesco, Anna Ghelli, Silvia Lemma, Anna Myriam Perrone, Ivana Kurelac, Luisa Iommarini, Anna Maria Porcelli, Giuseppe Gasparre
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Anticancer strategies aimed at inhibiting Complex I of the mitochondrial respiratory chain are increasingly being attempted in solid tumors, as functional oxidative phosphorylation is vital for cancer cells. Using ovarian cancer as a model,
Externí odkaz:
https://doaj.org/article/f6c0020e026341938aa41b0992088638
Autor:
Thomas GP Grünewald, Marta Alonso, Sofia Avnet, Ana Banito, Stefan Burdach, Florencia Cidre‐Aranaz, Gemma Di Pompo, Martin Distel, Heathcliff Dorado‐Garcia, Javier Garcia‐Castro, Laura González‐González, Agamemnon E Grigoriadis, Merve Kasan, Christian Koelsche, Manuela Krumbholz, Fernando Lecanda, Silvia Lemma, Dario L Longo, Claudia Madrigal‐Esquivel, Álvaro Morales‐Molina, Julian Musa, Shunya Ohmura, Benjamin Ory, Miguel Pereira‐Silva, Francesca Perut, Rene Rodriguez, Carolin Seeling, Nada Al Shaaili, Shabnam Shaabani, Kristina Shiavone, Snehadri Sinha, Eleni M Tomazou, Marcel Trautmann, Maria Vela, Yvonne MH Versleijen‐Jonkers, Julia Visgauss, Marta Zalacain, Sebastian J Schober, Andrej Lissat, William R English, Nicola Baldini, Dominique Heymann
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 11, Pp n/a-n/a (2020)
Abstract Sarcomas are heterogeneous and clinically challenging soft tissue and bone cancers. Although constituting only 1% of all human malignancies, sarcomas represent the second most common type of solid tumors in children and adolescents and compr
Externí odkaz:
https://doaj.org/article/32421af97ff64f339c73c8bfd6f57409
Autor:
Sofia Avnet, Silvia Lemma, Margherita Cortini, Gemma Di Pompo, Francesca Perut, Nicola Baldini
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Mesenchymal stromal cells (MSC) have essential functions in building and supporting the tumour microenvironment, providing metastatic niches, and maintaining cancer hallmarks, and it is increasingly evident that the study of the role of MSC in cancer
Externí odkaz:
https://doaj.org/article/8448dce963a2480988b657765cabc2ee
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0149481 (2016)
The characterization of cancer stem cell (CSC) subpopulation, through the comparison of the gene expression signature in respect to the native cancer cells, is particularly important for the identification of novel and more effective anticancer strat
Externí odkaz:
https://doaj.org/article/81a987d2dc0b458da72aa9a8c7835fc2
Autor:
Antonio S. Guillén Suárez, Alessandra Stefan, Silvia Lemma, Emanuele Conte, Alejandro Hochkoeppler
Publikováno v:
BioTechniques, Vol 53, Iss 2, Pp 99-103 (2012)
A coupled enzyme assay able to monitor the kinetics of reactions catalyzed by phosphate- or pyrophosphate-releasing enzymes is presented here. The assay is based on the concerted action of inorganic pyrophosphatase (PPase), purine nucleoside phosphor
Externí odkaz:
https://doaj.org/article/bb7feb20da6442e2b6c3ed643b299932
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 10, p 2930 (2018)
Similar to other types of cancer, acidification of tumor microenvironment is an important feature of osteosarcoma, and a major source of cellular stress that triggers cancer aggressiveness, drug resistance, and progression. Among the different effect
Externí odkaz:
https://doaj.org/article/18a0fd156b6d40239fdabc2f8cbcbb51
Autor:
Monica De Luise, Anna Maria Porcelli, Silvia Lemma, Manuela Sollazzo, Giuseppe Gasparre, Stefano Miglietta, Luisa Iommarini, Maria Iorio, Sara Milioni, Licia Bressi, Ivana Kurelac
Publikováno v:
The FEBS Journal. 289:8003-8019
Mitochondria act as key organelles in cellular bioenergetics and biosynthetic processes producing signals that regulate different molecular networks for proliferation and cell death. This ability is also preserved in pathologic contexts such as tumor
Autor:
Daniele Pirone, Daniele Sirico, Lisa Miccio, Vittorio Bianco, Martina Mugnano, Danila del Giudice, Gianandrea Pasquinelli, Sabrina Valente, Silvia Lemma, Luisa Iommarini, Ivana Kurelac, Pasquale Memmolo, Pietro Ferraro
The most recent discoveries in the biochemical field are highlighting the increasingly important role of lipid droplets (LDs) in several regulatory mechanisms in living cells. LDs are dynamic organelles and therefore their complete characterization i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d3ad647447dce222bbdab307f81b6a4
https://doi.org/10.1101/2021.12.09.471789
https://doi.org/10.1101/2021.12.09.471789
Publikováno v:
Cancer Metastasis Reviews
Skeletal involvement is a frequent and troublesome complication in advanced cancers. In the process of tumor cells homing to the skeleton to form bone metastases (BM), different mechanisms allow tumor cells to interact with cells of the bone microenv