Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Silvia Kuhls"'
Autor:
Marc Lambelet, Paulus Kirchhof, Silvia Kuhls, Pierre Amarenco, Alexander G.G. Turpie, Miriam Bach, Xantus Investigators, Sylvia Haas, A. John Camm
Publikováno v:
Clinical Cardiology
Background The XANTUS study (NCT01606995) demonstrated low rates of stroke and major bleeding in patients with atrial fibrillation (AF) receiving rivaroxaban in clinical practice for the prevention of thromboembolic events (N = 6784). Hypothesis Beca
Autor:
A. John Camm, Alexander G.G. Turpie, Pierre Amarenco, Susanne Hess, Silvia Kuhls, Xantus Investigators, Craig I Coleman, Thomas Evers, Paulus Kirchhof, Sylvia Haas
Publikováno v:
Clinical Cardiology. 39:565-569
Background The efficacy, safety, and ease of use of rivaroxaban may reduce anticoagulation-treatment burden and improve nonvalvular atrial fibrillation (NVAF) patient satisfaction compared with vitamin K antagonists (VKAs). Hypothesis Transitioning f
Autor:
Ed Waddingham, Silvia Kuhls, Richard Nixon, Gemma Hodgson, Christoph Dierig, Shahrul Mt-Isa, Thai-Son Tong, Andrew Thomson, John Stuart Pears, Isabelle Stöckert, Kimberley Hockley
Publikováno v:
Biometrical Journal. 58:8-27
While benefit-risk assessment is a key component of the drug development and maintenance process, it is often described in a narrative. In contrast, structured benefit-risk assessment builds on established ideas from decision analysis and comprises a
Autor:
Craig I, Coleman, Sylvia, Haas, Alexander G G, Turpie, Silvia, Kuhls, Susanne, Hess, Thomas, Evers, Pierre, Amarenco, Paulus, Kirchhof, A John, Camm
Publikováno v:
Clinical cardiology. 39(10)
BACKGROUND: The efficacy, safety, and ease of use of rivaroxaban may reduce anticoagulation‐treatment burden and improve nonvalvular atrial fibrillation (NVAF) patient satisfaction compared with vitamin K antagonists (VKAs). HYPOTHESIS: Transitioni
Autor:
Ursula Gather, Silvia Kuhls, Jürgen Schölmerich, Christian E. Wrede, Julia Langgartner, Sylvia Siebig, Michael Reng, Michael Imhoff
Publikováno v:
Journal of Critical Care. 25:128-135
Introduction Monitoring of physiologic parameters in critically ill patients is currently performed by threshold alarm systems with high sensitivity but low specificity. As a consequence, a multitude of alarms are generated, leading to an impaired cl
Autor:
Michael Imhoff, T. Bein, S. Bele, Thomas Müller, Silvia Kuhls, Ursula Gather, Sylvia Siebig, B. Trabold, Christian E. Wrede
Publikováno v:
Der Anaesthesist. 58:240-246
INTRODUCTION Cardiovascular monitoring alarms are frequent in intensive care units (ICUs) and lead to noise levels often exceeding 80 dB. The aim of this study was to evaluate if there are relevant differences between ICUs with different subspecialti
Autor:
Bayer Ag, Martin van Eickels, Silvia Kuhls, Paulus Kirchhof, A. John Camm, Susanne Hess, Sylvia Haas, Alexander Turpie, Pierre Amarenco, Marc Lambelet
Publikováno v:
Journal of the American College of Cardiology. 69:438
Background: Rivaroxaban was noninferior to warfarin in stroke or systemic embolism prevention in patients with nonvalvular atrial fibrillation (NVAF) in the ROCKET AF randomized controlled trial. Real-world evidence from XANTUS in an unselected rivar
Autor:
Richard, Nixon, Christoph, Dierig, Shahrul, Mt-Isa, Isabelle, Stöckert, Thaison, Tong, Silvia, Kuhls, Gemma, Hodgson, John, Pears, Ed, Waddingham, Kimberley, Hockley, Andrew, Thomson
Publikováno v:
Biometrical journal. Biometrische Zeitschrift. 58(1)
While benefit-risk assessment is a key component of the drug development and maintenance process, it is often described in a narrative. In contrast, structured benefit-risk assessment builds on established ideas from decision analysis and comprises a
Autor:
Jürgen Schölmerich, Ursula Gather, Michael Imhoff, Sylvia Siebig, Silvia Kuhls, Christian E. Wrede
Publikováno v:
Critical care medicine. 38(2)
To validate cardiovascular alarms in critically ill patients in an experimental setting by generating a database of physiologic data and clinical alarm annotations, and report the current rate of alarms and their clinical validity. Currently, monitor
Publikováno v:
Best practiceresearch. Clinical anaesthesiology. 23(1)
Alarms in medical devices are a matter of concern in critical and perioperative care. The high rate of false alarms is not only a nuisance for patients and caregivers, but can also compromise patient safety and effectiveness of care. The development