Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Silvia Jimeno-González"'
Autor:
Sonia Jimeno, Rosario Prados-Carvajal, María Jesús Fernández-Ávila, Sonia Silva, Domenico Alessandro Silvestris, Martín Endara-Coll, Guillermo Rodríguez-Real, Judit Domingo-Prim, Fernando Mejías-Navarro, Amador Romero-Franco, Silvia Jimeno-González, Sonia Barroso, Valeriana Cesarini, Andrés Aguilera, Angela Gallo, Neus Visa, Pablo Huertas
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Different roles of specific RNA-related factors in DNA repair have now been reported. Here the authors reveal a role for RNA-editing by ADAR in DNA end resection following double strand break formation and a change in pattern of ADAR2-mediated A-to-I
Externí odkaz:
https://doaj.org/article/09d9d77f3a254b6e952ffa2219df630e
Autor:
Fernando M. Delgado-Chaves, Pedro Manuel Martínez-García, Andrés Herrero-Ruiz, Francisco Gómez-Vela, Federico Divina, Silvia Jimeno-González, Felipe Cortés-Ledesma
Publikováno v:
Data in Brief, Vol 44, Iss , Pp 108499- (2022)
Type II DNA topoisomerases relax topological stress by transiently gating DNA passage in a controlled cut-and-reseal mechanism that affects both DNA strands. Therefore, they are essential to overcome topological problems associated with DNA metabolis
Externí odkaz:
https://doaj.org/article/d89eac8543cc469fb29754a4a04edb84
Autor:
Alejandro Álvarez-Quilón, José Terrón-Bautista, Irene Delgado-Sainz, Almudena Serrano-Benítez, Rocío Romero-Granados, Pedro Manuel Martínez-García, Silvia Jimeno-González, Cristina Bernal-Lozano, Cristina Quintero, Lourdes García-Quintanilla, Felipe Cortés-Ledesma
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
The ATM kinase is a key regulator of the DNA damage response to double-strand breaks (DSBs) and its homozygous loss in patients predisposes to lymphoid malignancies. Here, the authors develop a Tdp2 −/− Atm −/− double-deficient mouse model to
Externí odkaz:
https://doaj.org/article/9f1676662817487ea864a82ec0a5a86d
Autor:
Andrés Herrero-Ruiz, Pedro Manuel Martínez-García, José Terrón-Bautista, Gonzalo Millán-Zambrano, Jenna Ariel Lieberman, Silvia Jimeno-González, Felipe Cortés-Ledesma
Publikováno v:
Cell Reports, Vol 35, Iss 2, Pp 108977- (2021)
Summary: Accumulation of topological stress in the form of DNA supercoiling is inherent to the advance of RNA polymerase II (Pol II) and needs to be resolved by DNA topoisomerases to sustain productive transcriptional elongation. Topoisomerases are t
Externí odkaz:
https://doaj.org/article/8dfac8784fd141728490e80ccebfe46c
Autor:
Weijun Feng, Daisuke Kawauchi, Huiqin Körkel-Qu, Huan Deng, Elisabeth Serger, Laura Sieber, Jenna Ariel Lieberman, Silvia Jimeno-González, Sander Lambo, Bola S. Hanna, Yassin Harim, Malin Jansen, Anna Neuerburg, Olga Friesen, Marc Zuckermann, Vijayanad Rajendran, Jan Gronych, Olivier Ayrault, Andrey Korshunov, David T. W. Jones, Marcel Kool, Paul A. Northcott, Peter Lichter, Felipe Cortés-Ledesma, Stefan M. Pfister, Hai-Kun Liu
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Mutations in the chromatin modifier Chd7 have been associated with CHARGE syndrome and other developmental disorders. Here the authors show that Chd7 is required for the activation of genes essential for cerebellar granule cell differentiation, and t
Externí odkaz:
https://doaj.org/article/a402443280f6419d867e3b5b78b484b1
Autor:
Vicent Pelechano, Silvia Jimeno-González, Alfonso Rodríguez-Gil, José García-Martínez, José E Pérez-Ortín, Sebastián Chávez
Publikováno v:
PLoS Genetics, Vol 5, Iss 8, p e1000614 (2009)
Transcription elongation by RNA polymerase II was often considered an invariant non-regulated process. However, genome-wide studies have shown that transcriptional pausing during elongation is a frequent phenomenon in tightly-regulated metazoan genes
Externí odkaz:
https://doaj.org/article/70e1aa7b2b854d0388dcbf48c0eb5e77
Autor:
Manuela Vanti, Edurne Gallastegui, Iñaki Respaldiza, Alfonso Rodríguez-Gil, Fernando Gómez-Herreros, Silvia Jimeno-González, Albert Jordan, Sebastián Chávez
Publikováno v:
PLoS Genetics, Vol 5, Iss 1, p e1000339 (2009)
Rebound of HIV viremia after interruption of anti-retroviral therapy is due to the small population of CD4+ T cells that remain latently infected. HIV-1 transcription is the main process controlling post-integration latency. Regulation of HIV-1 trans
Externí odkaz:
https://doaj.org/article/1c8cb9d0957e4ebb9977631b1cc9e5ba
Autor:
Manuela Vanti, Edurne Gallastegui, Iñaki Respaldiza, Alfonso Rodríguez-Gil, Fernando Gómez-Herreros, Silvia Jimeno-González, Albert Jordan, Sebastián Chávez
Publikováno v:
PLoS Genetics, Vol 5, Iss 1 (2009)
Externí odkaz:
https://doaj.org/article/adefbcdd00564b3f8909f403c37348c4
Autor:
Laura Payán-Bravo, Esther Lara, Sara Fontalva, Yosu Odriozola-Gil, Sebastián Chávez, Silvia Jimeno-González, Ildefonso Cases, Carles Suñé, Yerma Pareja-Sanchez, José Antonio Guerrero-Martínez, Xenia Peñate, Jose C. Reyes, Mari Cruz Muñoz-Centeno
Publikováno v:
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
Digital.CSIC. Repositorio Institucional del CSIC
idUS: Depósito de Investigación de la Universidad de Sevilla
Universidad de Sevilla (US)
Nucleic Acids Research
instname
Digital.CSIC. Repositorio Institucional del CSIC
idUS: Depósito de Investigación de la Universidad de Sevilla
Universidad de Sevilla (US)
Nucleic Acids Research
Prefoldin is a heterohexameric complex conserved from archaea to humans that plays a cochaperone role during the co-translational folding of actin and tubulin monomers. Additional functions of prefoldin have been described, including a positive contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ca2dd77cba67057550c36122010a247
http://hdl.handle.net/10261/309906
http://hdl.handle.net/10261/309906
Autor:
Silvia Jimeno-González
En asignaturas de genética, aprender a resolver problemas es esencial para fortalecer la integración de los conceptos que se imparten en las clases teóri- cas. De hecho, el modelo metodológico tradicional suele basarse en la exposición teórica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6311cb3b015e359745b2f972c780b751
https://doi.org/10.12795/9788447222865.021
https://doi.org/10.12795/9788447222865.021