Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Silvia Jansen"'
Autor:
David J. Kast, Silvia Jansen
Publikováno v:
European Journal of Cell Biology, Vol 102, Iss 4, Pp 151363- (2023)
In vitro reconstitution assays using purified actin have greatly improved our understanding of cytoskeletal dynamics and their regulation by actin-binding proteins. However, early purification methods consisted of harsh conditions to obtain pure acti
Externí odkaz:
https://doaj.org/article/30fa2bc9551b49d1848a86dd6ab01805
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Plastin-3 (PLS3) is a calcium-sensitive actin-bundling protein that has recently been linked to the development of childhood-onset osteoporosis. Clinical data suggest that PLS3 mutations lead to a defect in osteoblast function, however the underlying
Externí odkaz:
https://doaj.org/article/38f9f057efb6490cba2c215e65599369
Autor:
Marion David, Estelle Wannecq, Françoise Descotes, Silvia Jansen, Blandine Deux, Johnny Ribeiro, Claire-Marie Serre, Sandra Grès, Nathalie Bendriss-Vermare, Mathieu Bollen, Simone Saez, Junken Aoki, Jean-Sébastien Saulnier-Blache, Philippe Clézardin, Olivier Peyruchaud
Publikováno v:
PLoS ONE, Vol 5, Iss 3, p e9741 (2010)
Bone metastases are highly frequent complications of breast cancers. Current bone metastasis treatments using powerful anti-resorptive agents are only palliative indicating that factors independent of bone resorption control bone metastasis progressi
Externí odkaz:
https://doaj.org/article/7845bd0a186844a298c4435a219c66b9
Publikováno v:
Circulation Research. 131
Actin, which is expressed in all eukaryotic cells, is an essential component of the cardiac and skeletal muscle sarcomere thin filament. Mutations in actin have been associated with a wide range of diseases, including skeletal myopathies and cardiomy
Autor:
Samantha M. Chin, Tomoyuki Hatano, Lavanya Sivashanmugam, Andrejus Suchenko, Anna S. Kashina, Mohan K. Balasubramanian, Silvia Jansen
Publikováno v:
Journal of Biological Chemistry. 298:102518
The great diversity in actin network architectures and dynamics is exploited by cells to drive fundamental biological processes, including cell migration, endocytosis, and cell division. While it is known that this versatility is the result of the ma
Autor:
Bruce L. Goode, Silvia Jansen
Publikováno v:
Molecular Biology of the Cell
Cellular actin networks exhibit diverse filamentous architectures and turnover dynamics, but how these differences are specified remains poorly understood. Here, we used multicolor total internal reflection fluorescence microscopy to ask how decorati
Autor:
Silvia Jansen, Enas Abu-Shah, Alex Mogilner, Bruce L. Goode, Kinneret Keren, Maya Malik-Garbi, Niv Ierushalmi
Publikováno v:
Nature physics
Contractile actomyosin network flows are crucial for many cellular processes including cell division and motility, morphogenesis and transport. How local remodelling of actin architecture tunes stress production and dissipation and regulates large-sc
Autor:
Mohan K. Balasubramanian, Lavanya Sivashanmugam, Tomoyuki Hatano, Andrejus Suchenko, Silvia Jansen, Anna Kashina, Samantha M. Chin
The great diversity in actin network architectures and dynamics is exploited by cells to drive fundamental biological processes, including cell migration, endocytosis and cell division. While it is known that this versatility is the result of the man
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c827a27bd37e7a0634a61222af1b9113
https://doi.org/10.1101/2020.06.25.172320
https://doi.org/10.1101/2020.06.25.172320
Publikováno v:
Journal of molecular biology, vol 427, iss 19
High rates of actin filament turnover are essential for many biological processes and require the activities of multiple actin-binding proteins working in concert. The mechanistic role of the actin filament severing protein cofilin is now firmly esta
Autor:
Adam B. Johnston, Bruce L. Goode, Silvia Jansen, Danielle Bellavance, Jaclyn Weinstein, Casey A. Ydenberg
Publikováno v:
Cytoskeleton. 72:349-361
The patterning of actin cytoskeleton structures in vivo is a product of spatially and temporally regulated polymer assembly balanced by polymer disassembly. While in recent years our understanding of actin assembly mechanisms has grown immensely, our