Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Silvia J. H. Park"'
Publikováno v:
eLife, Vol 5 (2016)
Visual processing depends on specific computations implemented by complex neural circuits. Here, we present a circuit-inspired model of retinal ganglion cell computation, targeted to explain their temporal dynamics and adaptation to contrast. To loca
Externí odkaz:
https://doaj.org/article/a268cf598cac473a88943ada7e61ce01
Autor:
Jiang-Bin Ke, Pouyan Rahmani, Evan E. Lieberman, Kevin L. Briggman, Joshua H. Singer, Na Young Jun, In-Jung Kim, Nao Rho, Hae-Jim Lee, Silvia J. H. Park, Jonathan B. Demb, Padideh Ghorbani
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
Night vision in mammals depends fundamentally on rod photoreceptors and the well-studied rod bipolar (RB) cell pathway. The central neuron in this pathway, the AII amacrine cell (AC), exhibits a spatially tuned receptive field, composed of an excitat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57a21d7c5f2da2106b5202d46783c7c5
https://doi.org/10.1101/2020.02.24.963868
https://doi.org/10.1101/2020.02.24.963868
Autor:
Pouyan Rahmani, In-Jung Kim, Jiang-Bin Ke, Joseph Pottackal, Na Young Jun, Joshua H. Singer, Jonathan B. Demb, Silvia J. H. Park
Publikováno v:
The Journal of Neuroscience. 38:3753-3766
Inhibitory interneurons sculpt the outputs of excitatory circuits to expand the dynamic range of information processing. In mammalian retina, >30 types of amacrine cells provide lateral inhibition to vertical, excitatory bipolar cell circuits, but fu
Autor:
Bart G. Borghuis, Jonathan B. Demb, In-Jung Kim, Pouyan Rahmani, Silvia J. H. Park, Qiang Zeng
Publikováno v:
Journal of Neuroscience. 35:10685-10700
Visual processing in the retina depends on coordinated signaling by interneurons. Photoreceptor signals are relayed to ∼20 ganglion cell types through a dozen excitatory bipolar interneurons, each responsive to light increments (ON) or decrements (
Autor:
Silvia J. H. Park, Bo Chen, Bhupesh Mehta, Xinran Liu, Ethan J. Mohns, Kai Yao, Michael C. Crair, Suo Qiu, Yanbin V. Wang, Bo Chang, Jonathan B. Demb, David Zenisek
Publikováno v:
Nature. 560(7719)
In zebrafish, Muller glia (MG) are a source of retinal stem cells that can replenish damaged retinal neurons and restore vision1. In mammals, however, MG do not spontaneously re-enter the cell cycle to generate a population of stem or progenitor cell
Publikováno v:
Journal of Neurophysiology. 112:1950-1962
Retinal bipolar cells (BCs) transmit visual signals in parallel channels from the outer to the inner retina, where they provide glutamatergic inputs to specific networks of amacrine and ganglion cells. Intricate network computation at BC axon termina
Publikováno v:
The Journal of Neuroscience. 34:3976-3981
Direction selectivity represents a fundamental visual computation. In mammalian retina, On-Off direction-selective ganglion cells (DSGCs) respond strongly to motion in a preferred direction and weakly to motion in the opposite, null direction. Electr
Publikováno v:
eLife, Vol 5 (2016)
eLife
eLife
Visual processing depends on specific computations implemented by complex neural circuits. Here, we present a circuit-inspired model of retinal ganglion cell computation, targeted to explain their temporal dynamics and adaptation to contrast. To loca
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 34(5)
In the developing mouse retina, spontaneous and light-driven activity shapes bipolar→ganglion cell glutamatergic synapse formation, beginning around the time of eye-opening (P12–P14) and extending through the first postnatal month. During this ti