Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Silvia Gravina"'
Autor:
Xiao Dong, Miao Shi, Moonsook Lee, Rafael Toro, Silvia Gravina, Weiguo Han, Shoya Yasuda, Tao Wang, Zhengdong Zhang, Jan Vijg, Yousin Suh, Simon D. Spivack
Publikováno v:
Epigenetics, Vol 13, Iss 3, Pp 264-274 (2018)
Gene regulatory analysis of highly diverse human tissues in vivo is essentially constrained by the challenge of performing genome-wide, integrated epigenetic and transcriptomic analysis in small selected groups of specific cell types. Here we perform
Externí odkaz:
https://doaj.org/article/789469de19aa403baac2a5d9529938b2
Autor:
Bo Yu, Xiao Dong, Silvia Gravina, Önder Kartal, Timothy Schimmel, Jacques Cohen, Drew Tortoriello, Raifa Zody, R. David Hawkins, Jan Vijg
Publikováno v:
Stem Cell Reports, Vol 9, Iss 1, Pp 397-407 (2017)
The establishment of DNA methylation patterns in oocytes is a highly dynamic process marking gene-regulatory events during fertilization, embryonic development, and adulthood. However, after epigenetic reprogramming in primordial germ cells, how and
Externí odkaz:
https://doaj.org/article/4841ff0b579d49b98253a46e84570848
Autor:
Elaine C. Maggi, Silvia Gravina, Haiying Cheng, Bilal Piperdi, Ziqiang Yuan, Xiao Dong, Steven K. Libutti, Jan Vijg, Cristina Montagna
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
The goal of this study was to develop a method for whole genome cell-free DNA (cfDNA) methylation analysis in humans and mice with the ultimate goal to facilitate the identification of tumor derived DNA methylation changes in the blood. Plasma or ser
Externí odkaz:
https://doaj.org/article/9d957a29de5c4a079f02b0ce9d94941b
Autor:
Silvia Gravina, Martijn E T Dollé, Tao Wang, Harry van Steeg, Paul Hasty, Jan Hoeijmakers, Jan Vijg
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73496 (2013)
A gradual loss of the correct patterning of 5-methyl cytosine marks in gene promoter regions has been implicated in aging and age-related diseases, most notably cancer. While a number of studies have examined DNA methylation in aging, there is no con
Externí odkaz:
https://doaj.org/article/6829ad199ed34c4b9b7b3a740b352731
Autor:
Silvia Gravina, Bo Yu, Xiao Dong, Önder Kartal, R. David Hawkins, Raifa Zody, Timothy Schimmel, Drew Tortoriello, Jan Vijg, Jacques Cohen
Publikováno v:
Stem Cell Reports, Vol 9, Iss 1, Pp 397-407 (2017)
Stem Cell Reports
Stem Cell Reports
Summary The establishment of DNA methylation patterns in oocytes is a highly dynamic process marking gene-regulatory events during fertilization, embryonic development, and adulthood. However, after epigenetic reprogramming in primordial germ cells,
Autor:
Jan Vijg, Zhengdong D. Zhang, Simon D. Spivack, Miao Shi, Weiguo Han, Rafael Toro, Silvia Gravina, Moonsook Lee, Yousin Suh, Tao Wang, Xiao Dong, Shoya Yasuda
Publikováno v:
Epigenetics. 13(3)
Gene regulatory analysis of highly diverse human tissues in vivo is essentially constrained by the challenge of performing genome-wide, integrated epigenetic and transcriptomic analysis in small selected groups of specific cell types. Here we perform
Autor:
Huda Adwan-Shekhidem, Gil Atzmon, Bérénice A. Benayoun, John D. Bowman, Kim V.E. Braun, Ramón Cacabelos, Paola Caiafa, Xiaohua Cao, Mahua Choudhury, Rajiv Chowdhury, Fabio Ciccarone, Vincent T. Cunliffe, Weiwei Dang, Xiao Dong, Helen Eachus, Oscar H. Franco, Silvia Gravina, Alexander K. Koliada, Igor Kovalchuk, Tilen Kranjc, Anna Kudryavtseva, Vineet Kumar, Simon C. Langley-Evans, Wil A.M. Loenen, Nika Lovšin, Oleh V. Lushchak, Janja Marc, Sunitha Meruvu, Ken I. Mills, Arnold B. Mitnitski, Alexey Moskalev, Beverly S. Muhlhausler, Taulant Muka, Jana Nano, Justin M. O’Sullivan, Barbara Ostanek, Eliana Portilla, Ken Raj, Irene M. Rea, Clare M. Reynolds, Axel Schumacher, Robert A. Seaborne, Stephanie A. Segovia, Mikhail Shaposhnikov, Adam P. Sharples, Ilya Solovev, Claire E. Stewart, Oscar Teijido, Jenna Troup, Duygu Ucar, Alexander M. Vaiserman, Mukesh Verma, Mark H. Vickers, Jan Vijg, Trudy Voortman, Xiangru Xu, Michele Zampieri, Janja Zupan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::659a973da7210f3bab7a5e2f66303963
https://doi.org/10.1016/b978-0-12-811060-7.01002-0
https://doi.org/10.1016/b978-0-12-811060-7.01002-0
DNA methylation is a critical epigenetic marker involved in development, differentiation, and cell fate diversity. Here we discuss the possible role of adaptive and stochastic changes in DNA methylation in aging. We describe recent progress in studyi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8140fbc0b2de226fb6e0aa158b653177
https://doi.org/10.1016/b978-0-12-811060-7.00009-7
https://doi.org/10.1016/b978-0-12-811060-7.00009-7
Autor:
Stephen Hartley, Alice Ignezweski, Bo Yu, Valya R. Russanova, Silvia Gravina, James C. Mullikin, Bruce H. Howard, James H. Segars, Alan H. DeCherney, J.R. Graham
Publikováno v:
Oncotarget
// Bo Yu 1 , Valya R. Russanova 2 , Silvia Gravina 3 , Stephen Hartley 4 , James C. Mullikin 4, 5 , Alice Ignezweski 6 , James Graham 6 , James H. Segars 7 , Alan H. DeCherney 7 , Bruce H. Howard 2 1 Department of Obstetrics and Gynecology & Women's
Publikováno v:
Aging Cell
Summary Free circulating or cell‐free DNA (cfDNA), possibly from dying cells that release their contents into the blood as they break down, have become of major interest as a source for noninvasive diagnostics. Recent work demonstrated the uptake o