Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Silvia Grancara"'
Autor:
Silvia Grancara, Pamela Martinis, Lisa Dalla Via, Yuta Kanamori, Aída Nelly García-Argáez, Elena Pacella, Antonio Toninello, Enzo Agostinelli
Publikováno v:
Amino acids. 52(2)
Agmatine (AGM) produces a dual effect on the mitochondrial permeability transition (MPT) mechanism in rat liver mitochondria: at low concentrations, it induces the phenomenon, at high ones, inhibits it. The prevention at high concentrations is eviden
Autor:
Silvia Grancara, Shinji Ohkubo, Aída Nelly García-Argáez, Antonio Toninello, Enzo Agostinelli, Paolo Arcari, Gianluca Canettieri, Yuta Kanamori, Lisa Dalla Via
Publikováno v:
International Journal of Oncology.
Aged garlic extract (AGE) has been shown to possess therapeutic properties in cancer; however its mechanisms of action are unclear. In this study, we demonstrate by MTT assay that AGE exerts an anti-proliferative effect on a panel of both sensitive a
Autor:
Silvia Grancara, Aída Nelly García-Argáez, Lisa Dalla Via, Pamela Martinis, Mariano Martínez-Vázquez, Antonio Toninello
Publikováno v:
Current Pharmaceutical Design. 20:223-244
Mitochondria are the cell powerhouses but also contain the mechanisms leading to cell death. Many signals converge on mitochondria to cause the permeabilization of mitochondrial membranes by the mitochondrial permeability transition (MPT) induction a
Autor:
Lisa Dalla Via, Silvia Grancara, Antonio Toninello, Arianna Adami, Simona Samaritani, Luca Labella, Daniela Belli Dell'Amico, Pamela Martinis, Aída Nelly García-Argáez
Publikováno v:
Bioorganic & Medicinal Chemistry. 21:6965-6972
A convenient synthetic route and the characterization of complexes trans-[PtCl2(L)(PPh3)] (L=Et2NH (2), (PhCH2)2NH (3), (HOCH2CH2)2NH) (4) are reported. The antiproliferative activity was evaluated on three human tumor cell lines. The investigation o
Autor:
Massimiliano Magro, Davide Baratella, Fabio Vianello, Silvia Grancara, Antonio Toninello, Nicola Pianca, Radek Zboril
Publikováno v:
Sensors and Actuators B: Chemical. 176:315-322
A simple carbon paste electrode modified with novel maghemite (γ-Fe 2 O 3 ) nanoparticles, characterized by a mean diameter of about 10 nm and specific surface properties (called surface active maghemite nanoparticles, SAMNs) has been developed. The
Autor:
Silvia Grancara, Shinji Ohkubo, Marcantonio Bragadin, Lisa Dalla Via, Enzo Agostinelli, Antonio Toninello, Sabrina Manente, Elena Pacella, Aída Nelly García-Argáez
Spermine, besides to be transported in mitochondria by an energy dependent electrophoretic mechanism, can be also released by two different mechanisms. The first one is induced in deenergizing conditions by FCCP or antimycin A and it is mediated by a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1c6104c8932838e05182c4490a6ee10
http://hdl.handle.net/10278/3674243
http://hdl.handle.net/10278/3674243
Autor:
Silvia, Grancara, Bonaiuto, Emanuela, Martinis, Pamela, Marisa, Colone, Alberto, Macone, Roberto, Stevanato, Marcantonio, Bragadin, Vianello, Fabio, Toninello, Antonio, DI PAOLO, MARIA LUISA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3657::22c82ed51f137bd44f4ecebd4bc7c267
http://hdl.handle.net/11577/3192067
http://hdl.handle.net/11577/3192067
Autor:
Marcantonio Bragadin, Silvia Grancara, Antonio Toninello, Shinji Ohkubo, Sabrina Manente, Mauro Ciccariello, Marco Artico, Enzo Agostinelli
Mitochondria represent cell "powerhouses," being involved in energy transduction from the electrochemical gradient to ATP synthesis. The morphology of their cell types may change, according to various metabolic processes or osmotic pressure. A new mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::942f0fbe0ee00e9e9044205d99c6bd70
http://hdl.handle.net/11573/897519
http://hdl.handle.net/11573/897519
Autor:
Antonio Toninello, Silvia Grancara, Vito Di Noto, Pamela Martinis, Lisa Dalla Via, Stefania Saccoccio, Valentina Battaglia, Marcantonio Bragadin, Maria Angelica Grillo, Enzo Agostinelli
Publikováno v:
Amino Acids. 42:761-768
Agmatine, a divalent diamine with two positive charges at physiological pH, is transported into the matrix of liver mitochondria by an energy-dependent mechanism, the driving force of which is the electrical membrane potential. Its binding to mitocho
Autor:
Valentina Battaglia, Francisco P. S. C. Gil, Maria Paula M. Marques, Enzo Agostinelli, Silvia Grancara, Rita Calheiros, Nikenza Viceconte, Antonio Toninello, G. Tempera
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Polyamines are small cationic molecules required for cellular proliferation and are detected at higher concentrations in most tumour tissues, compared to normal tissues. Agmatine (AGM), a biogenic amine, is able to arrest proliferation in cell lines