Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Silvia Goebel"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Histological examination of targets in regions of interest in histological sections is one of the most frequently used tools in biomedical research. However, it is a technical challenge to secure a multitarget section for inspection of the s
Externí odkaz:
https://doaj.org/article/9f0f0e5e3d04448ba5124da17020cd9c
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0284444 (2023)
Traditional histological stains, such as hematoxylin-eosin (HE), special stains, and immunofluorescence (IF), have defined myriads of cellular phenotypes and tissue structures in a separate stained section. However, the precise connection of informat
Externí odkaz:
https://doaj.org/article/785adbdf99a348daa34b4ad2c65dff76
Autor:
Chao Han, Pengxuan Ren, Medina Mamtimin, Linus Kruk, Edita Sarukhanyan, Chenyu Li, Hans-Joachim Anders, Thomas Dandekar, Irena Krueger, Margitta Elvers, Silvia Goebel, Kristin Adler, Götz Münch, Thomas Gudermann, Attila Braun, Elmina Mammadova-Bach
Publikováno v:
Biomedicines, Vol 11, Iss 2, p 423 (2023)
Glycoprotein VI (GPVI) is a platelet-specific receptor for collagen and fibrin, regulating important platelet functions such as platelet adhesion and thrombus growth. Although the blockade of GPVI function is widely recognized as a potent anti-thromb
Externí odkaz:
https://doaj.org/article/baa6ba13cc5e43369b4b0d501f8dc336
Autor:
Stephan Zeibig, Manuela Büttcher, Silvia Goebel, Jessica Pauli, Annique Hunger, Martin Ungerer, Meinrad Gawaz, Götz Münch
Publikováno v:
Cellular Physiology and Biochemistry, Vol 52, Iss 4, Pp 681-695 (2019)
Externí odkaz:
https://doaj.org/article/4c41514e2a604d84a1f6134a46ccf8c2
Autor:
Teresa L. Krammer, Stephan Zeibig, Waltraud C. Schrottmaier, Anita Pirabe, Silvia Goebel, Andreas B. Diendorfer, Hans-Peter Holthoff, Alice Assinger, Matthias Hackl
Publikováno v:
Cells, Vol 11, Iss 8, p 1254 (2022)
Dysregulation of platelet function is causally connected to thrombus formation and cardiovascular diseases. Therefore, assessing platelet reactivity is crucial. However, current platelet function tests come with pitfalls, limiting clinical use. Plasm
Externí odkaz:
https://doaj.org/article/f22953e7465e427f8d89447c8e0eb377
Autor:
Silvia Goebel, Zhongmin Li, Jasmin Vogelmann, Hans-Peter Holthoff, Heidrun Degen, Dirk M Hermann, Meinrad Gawaz, Martin Ungerer, Götz Münch
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e66960 (2013)
OBJECTIVES: We examined the effect of Revacept, an Fc fusion protein which is specifically linked to the extracellular domain of glycoprotein VI (GPVI), on thrombus formation after vessel wall injury and on experimental stroke in mice. BACKGROUND: Se
Externí odkaz:
https://doaj.org/article/937b3af4b40a4cc6996c43a0a8fe2f9b
Autor:
Martin Ungerer, Zhongmin Li, Christine Baumgartner, Silvia Goebel, Jasmin Vogelmann, Hans-Peter Holthoff, Meinrad Gawaz, Götz Münch
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71193 (2013)
AIMS: Glycoprotein VI (GPVI) is a key platelet receptor which mediates plaque-induced platelet activation and consecutive atherothrombosis, but GPVI is also involved in platelet-mediated atheroprogression. Therefore, interference in GPVI-mediated pla
Externí odkaz:
https://doaj.org/article/7f93eb77fe3d482d804c1b79735edc17
Autor:
Andreas Reimann, Zhongmin Li, Silvia Goebel, Julia Fassbender, Hans-Peter Holthoff, Meinrad Gawaz, Götz Münch, Martin Ungerer
Publikováno v:
Heart International, Vol 11, Iss 1, Pp 0-0 (2016)
BackgroundThrombolytic therapy with recombinant tissue plasminogen activator (rtPA) remains the only approved medication for acute ischemic stroke, but incurs significant bleeding risks. Therefore, approaches to combine lower doses of thrombolytic th
Externí odkaz:
https://doaj.org/article/d2f98ed9def6452f95059e9174aa3bac
Publikováno v:
Scientific reports. 12(1)
Histological examination of targets in regions of interest in histological sections is one of the most frequently used tools in biomedical research. However, it is a technical challenge to secure a multitarget section for inspection of the structure
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
A novel Histo-ELISA technique is intended to facilitate quantification of target tissue proteins in a tissue section and involves the selection of target regions in the tissue section, application of streptavidin-conjugated HRP (horseradish peroxidas