Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Silvia Gobbi"'
Publikováno v:
Molecules, Vol 29, Iss 15, p 3514 (2024)
The main feature of neurodegenerative diseases, including Alzheimer’s disease, is the network of complex and not fully recognized neuronal pathways and targets involved in their onset and progression. The therapeutic treatment, at present mainly sy
Externí odkaz:
https://doaj.org/article/cd936b4a81d54e1e9fc5958a16a1c1c7
Autor:
Silvia Gobbi, Silvia Martini, Riccardo Rozza, Angelo Spinello, Jessica Caciolla, Angela Rampa, Federica Belluti, Nadia Zaffaroni, Alessandra Magistrato, Alessandra Bisi
Publikováno v:
Molecules, Vol 28, Iss 7, p 3047 (2023)
Despite the significant outcomes attained by scientific research, breast cancer (BC) still represents the second leading cause of death in women. Estrogen receptor-positive (ER+) BC accounts for the majority of diagnosed BCs, highlighting the disrupt
Externí odkaz:
https://doaj.org/article/490739d2f57d4600af5462103c1d52c4
Autor:
Martina Rossi, Concettina Cappadone, Giovanna Picone, Alessandra Bisi, Giovanna Farruggia, Federica Belluti, Paolo Blasi, Silvia Gobbi, Emil Malucelli
Publikováno v:
Molecules, Vol 27, Iss 12, p 3751 (2022)
Osteosarcoma (OS) is a malignant disease characterized by poor prognosis due to a high incidence of metastasis and chemoresistance. Recently, Licochalcone A (Lic-A) has been reported as a promising agent against OS. Starting from chalcones selected f
Externí odkaz:
https://doaj.org/article/2608acf1e3a8415cb683cab22e131b75
Autor:
Sofia Burato, Luca Leonardi, Ippazio Cosimo Antonazzo, Emanuel Raschi, Chiara Ajolfi, Manuela Baraghini, Antonella Chiarello, Valentina Delmonte, Lucio Di Castri, Monia Donati, Antonella Fadda, Daniela Fedele, Alessandra Ferretti, Laura Gabrielli, Silvia Gobbi, Sereno Lughi, Martina Mazzari, Fabio Pieraccini, Alessandro Renzetti, Elsa Russi, Chiara Scanelli, Barbara Zanetti, Elisabetta Poluzzi
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2021)
Backround: We aimed at assessing the prevalence of polypharmacy and potential drug-drug interactions (DDIs) with clinical relevance in elderly patient on Emilia Romagna area. Both outpatients and residents in nursing homes were assessed, with only pa
Externí odkaz:
https://doaj.org/article/98803bfb94cd469dadd45a432c177a5e
Publikováno v:
Molecules, Vol 26, Iss 14, p 4228 (2021)
Naturally occurring flavonoids are found as secondary metabolites in a wide number of plants exploited for both medicine and food and have long been known to be endowed with multiple biological activities, making them useful tools for the treatment o
Externí odkaz:
https://doaj.org/article/acca19fd495049df93638179cc92dbcf
Autor:
Serena Montanari, Marco Allarà, Laura Scalvini, Magdalena Kostrzewa, Federica Belluti, Silvia Gobbi, Marina Naldi, Silvia Rivara, Manuela Bartolini, Alessia Ligresti, Alessandra Bisi, Angela Rampa
Publikováno v:
Molecules, Vol 26, Iss 11, p 3254 (2021)
In the last years, the connection between the endocannabinoid system (eCS) and neuroprotection has been discovered, and evidence indicates that eCS signaling is involved in the regulation of cognitive processes and in the pathophysiology of Alzheimer
Externí odkaz:
https://doaj.org/article/327bb9f79f8b4cd9ac8571294fb57f21
Publikováno v:
Molecules, Vol 25, Iss 22, p 5351 (2020)
The current therapeutic approach for the treatment of hormone dependent breast cancer includes interference with estrogen receptors via either selective modulators or estrogens deprivation, by preventing their biosynthesis with aromatase inhibitors.
Externí odkaz:
https://doaj.org/article/438145af05ef4490a5bc2dcc612bac4a
Autor:
Francesca Seghetti, Rita Maria Concetta Di Martino, Elena Catanzaro, Alessandra Bisi, Silvia Gobbi, Angela Rampa, Barbara Canonico, Mariele Montanari, Dmitri V. Krysko, Stefano Papa, Carmela Fimognari, Federica Belluti
Publikováno v:
Molecules, Vol 25, Iss 13, p 3066 (2020)
The burden of neoplastic diseases is widely recognized as a severe cause of mortality. The clinical inadequacy of most anticancer therapeutics urgently prompted intense drug discovery efforts toward the identification of new chemical entities endowed
Externí odkaz:
https://doaj.org/article/9a79b61846734e9dbe01cea2a04d770b
Autor:
Francesca Bonvicini, Giovanna A. Gentilomi, Francesca Bressan, Silvia Gobbi, Angela Rampa, Alessandra Bisi, Federica Belluti
Publikováno v:
Molecules, Vol 24, Iss 2, p 372 (2019)
The occurrence of invasive fungal infections represents a substantial threat to human health that is particularly serious in immunocompromised patients. The limited number of antifungal agents, devoid of unwanted toxic effects, has resulted in an inc
Externí odkaz:
https://doaj.org/article/db71c100eba44917b240ef2ad528d2c9
Autor:
Alessandra Bisi, Matteo Micucci, Silvia Gobbi, Federica Belluti, Roberta Budriesi, Angela Rampa
Publikováno v:
Molecules, Vol 23, Iss 12, p 3088 (2018)
As a follow-up to our previous studies on differently substituted 1,4-dihydropyridines endowed with a peculiar cardiac selectivity, in this paper, a small series of hybrid compounds bearing the pharmacophore fragment of lidoflazine in position 2 or 3
Externí odkaz:
https://doaj.org/article/6173268849ed41c8ae6fb83135f57cc5