Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Silvia Gines"'
Autor:
Alba Ramon-Lainez, Esther García García, Daniel Del Toro, Georgia Escaramís, Laura Lopez Molina, L Valls, G Garrabou, Eulàlia Martí, Silvia Gines, Mercè Masana, Jordi Alberch, Manuel J Rodríguez
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S482- (2023)
Externí odkaz:
https://doaj.org/article/dbca7e273a2c4174b8c5cc9d4d924b67
Publikováno v:
Neurobiology of Disease, Vol 136, Iss , Pp 104741- (2020)
Mitochondria-associated membranes (MAMs) are dynamic structures that communicate endoplasmic reticulum (ER) and mitochondria allowing calcium transfer between these two organelles. Since calcium dysregulation is an important hallmark of several neuro
Externí odkaz:
https://doaj.org/article/447b8eee8c6a4dc58f2c1bb4d720e0ea
Autor:
Manuel Daldin, Valentina Fodale, Cristina Cariulo, Lucia Azzollini, Margherita Verani, Paola Martufi, Maria Carolina Spiezia, Sean M. Deguire, Marta Cherubini, Douglas Macdonald, Andreas Weiss, Alberto Bresciani, Jean-Paul Gerard Vonsattel, Lara Petricca, J. Lawrence Marsh, Silvia Gines, Iolanda Santimone, Massimo Marano, Hilal A. Lashuel, Ferdinando Squitieri, Andrea Caricasole
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract Conformational changes in disease-associated or mutant proteins represent a key pathological aspect of Huntington’s disease (HD) and other protein misfolding diseases. Using immunoassays and biophysical approaches, we and others have recen
Externí odkaz:
https://doaj.org/article/28a4ca589dda4cb5b33f36313fe3c9c6
Autor:
Andrea Comella Bolla, Tony Valente, Andres Miguez, Veronica Brito, Silvia Gines, Carme Solà, Marco Straccia, Josep M Canals
Publikováno v:
PLoS ONE, Vol 14, Iss 12, p e0224901 (2019)
In Huntington's disease (HD), striatal medium spiny neurons (MSNs) are particularly sensitive to the presence of a CAG repeat in the huntingtin (HTT) gene. However, there are many evidences that cells from the peripheral immune system and central ner
Externí odkaz:
https://doaj.org/article/8a2fc1e286e7464291471f42703ea303
Autor:
Alice S. Chen-Plotkin, Ghazaleh Sadri-Vakili, George J. Yohrling, Melissa W. Braveman, Caroline L. Benn, Kelly E. Glajch, Derek P. DiRocco, Laurie A. Farrell, Dimitri Krainc, Silvia Gines, Marcy E. MacDonald, Jang-Ho J. Cha
Publikováno v:
Neurobiology of Disease, Vol 22, Iss 2, Pp 233-241 (2006)
Huntington's disease (HD) is a neurodegenerative disease caused by expansion of a polyglutamine tract within the huntingtin protein. Transcriptional dysregulation has been implicated in HD pathogenesis; recent evidence suggests a defect in Sp1-mediat
Externí odkaz:
https://doaj.org/article/84d817405df14df5b6f4b93444f827d8
Autor:
Todd W. Miller, Chun Zhou, Silvia Gines, Marcy E. MacDonald, Nicholas D. Mazarakis, Gillian P. Bates, James S. Huston, Anne Messer
Publikováno v:
Neurobiology of Disease, Vol 19, Iss 1, Pp 47-56 (2005)
Amino-terminal fragments of huntingtin (htt) appear to result from proteolytic processing of the full-length protein in Huntington's disease (HD), and fragments containing pathological expansions of polyglutamine elicit toxicity in model systems. Suc
Externí odkaz:
https://doaj.org/article/0e311aa0cb004cb39f70adfd691ae40c
Autor:
M. Teresa Bartual-Figueras, Joaquin Turmo-Garuz, Montserrat Cabré-Pairet, Andrés Coco-Prieto, Silvia Gines-Padrós, Maria López-Bartual, Dolores Rodríguez-Martín, Lorea Romero-Gutiérrez
Publikováno v:
INTED2023 Proceedings.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4d8d58b6f03592f21f2e33538ef7fa1
https://doi.org/10.21125/inted.2023.0657
https://doi.org/10.21125/inted.2023.0657
Autor:
Nadia Di Franco, Analia Bortolozzi, Leticia Campo, Marc Espina Cortes, Laura Lopez, Silvia Gines Padros
Publikováno v:
I: Experimental therapeutics – preclinical.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b1c9bb228dff19776d90e1b6a313604
https://doi.org/10.1136/jnnp-2022-ehdn.248
https://doi.org/10.1136/jnnp-2022-ehdn.248
Publikováno v:
Neurobiology of disease. 136
Mitochondria-associated membranes (MAMs) are dynamic structures that communicate endoplasmic reticulum (ER) and mitochondria allowing calcium transfer between these two organelles. Since calcium dysregulation is an important hallmark of several neuro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b6afd1573c9cdc995746b2d51ab0912a
https://pubmed.ncbi.nlm.nih.gov/31931142
https://pubmed.ncbi.nlm.nih.gov/31931142
The GRP78-PERK axis contributes to memory and synaptic impairments in Huntington's disease R6/1 mice
Autor:
Marc Espina, Nadia Di Franco, Martina Brañas-Navarro, Irene Rodriguez Navarro, Veronica Brito, Laura Lopez-Molina, Carlos Costas-Insua, Manuel Guzmán, Silvia Ginés
Publikováno v:
Neurobiology of Disease, Vol 184, Iss , Pp 106225- (2023)
Increasing evidence indicates that a key factor in neurodegenerative diseases is the activation of the unfolded protein response (UPR) caused by an accumulation of misfolded proteins in the endoplasmic reticulum (ER stress). Particularly, in Huntingt
Externí odkaz:
https://doaj.org/article/ede8d1825f004ae789741daebb76f3ed