Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Silvia Giannini"'
Autor:
Li Dai, Mayuko Uehara, Xiaofei Li, Brenna A. LaBarre, Naima Banouni, Takaharu Ichimura, Melissa M. Lee-Sundlov, Vivek Kasinath, Jade A. Sullivan, Heyu Ni, Francesca Barone, Silvia Giannini, Baharak Bahmani, Peter T. Sage, Nikolaos A. Patsopoulos, George C. Tsokos, Jonathan S. Bromberg, Karin Hoffmeister, Liwei Jiang, Reza Abdi
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Lymph nodes (LNs) are the critical sites of immunity, and the stromal cells of LNs are crucial to their function. Our understanding of the stromal compartment of the LN has deepened recently with the characterization of nontraditional stromal cells.
Externí odkaz:
https://doaj.org/article/3dc4347bd1d44db88e9d3b536cdd3e39
Autor:
Silvia Giannini, Melissa M. Lee-Sundlov, Leonardo Rivadeneyra, Christian A. Di Buduo, Robert Burns, Joseph T. Lau, Hervé Falet, Alessandra Balduini, Karin M. Hoffmeister
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Mutations affecting sialylation and galactosylation affect megakaryocyte function and thrombopoiesis. Here the authors show that the enzyme β4GalT1 regulates thrombopoiesis and hematopoietic stem cell homeostasis by controlling beta-1 integrin funct
Externí odkaz:
https://doaj.org/article/260eeeaaa02b43dda46cc8c8f666fa3c
Publikováno v:
Haematologica, Vol 95, Iss 6 (2010)
Platelet-type von Willebrand disease (PT-VWD) is a rare autosomal dominant bleeding disorder which is due to a mutation in the gene encoding for platelet glycoprotein Ibα (GPIbα) resulting in enhanced affinity for von Willebrand factor (VWF). PT-VW
Externí odkaz:
https://doaj.org/article/533237b7db7c4daca3c0c8b3839178de
Autor:
Paolo Gresele, Emanuela Falcinelli, Silvia Giannini, Pio D’Adamo, Angela D’Eustacchio, Teresa Corazzi, Anna Maria Mezzasoma, Filomena Di Bari, Giuseppe Guglielmini, Luca Cecchetti, Patrizia Noris, Carlo L. Balduini, Anna Savoia
Publikováno v:
Haematologica, Vol 94, Iss 5 (2009)
Background Defects of integrin αIIbβ3 are typical of Glanzmann’s thrombasthenia, an inherited autosomal recessive bleeding disorder characterized by the failure of platelets to aggregate in response to all physiological agonists, but with no abno
Externí odkaz:
https://doaj.org/article/2bf314dc62e945f1b1d87aded59a1c43
Publikováno v:
Haematologica, Vol 92, Iss 12 (2007)
Background and Objectives von Willebrand’s disease (VWD) is a heterogeneous bleeding disorder caused by quantitative or qualitative defects in von Willebrand factor (VWF). The diagnosis of VWD requires several laboratory tests. The aim of our study
Externí odkaz:
https://doaj.org/article/2b2cd856330842b0b096aeaf65fda299
Autor:
Ann Mullally, Fatima Al-Shahrour, Rebekka K. Schneider, Julie-Aurore Losman, Zuzana Tothova, Elizabeth A. Morgan, Ofir Wolach, Silvia Giannini, Natalie Florescu, Fabian Peisker, Amy Ko, Emily A. Rosen, Javier Perales-Patón, Edwin Chen, Nouran S. Abdelfattah, Shannon Elf
Supplementary Table S2. sgRNA sequences and Primer sequences used for CRISPR/Cas9 genome editing.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6743c05e93cadcc4fee91eeb313e3637
https://doi.org/10.1158/2159-8290.22531491
https://doi.org/10.1158/2159-8290.22531491
Autor:
Ann Mullally, Fatima Al-Shahrour, Rebekka K. Schneider, Julie-Aurore Losman, Zuzana Tothova, Elizabeth A. Morgan, Ofir Wolach, Silvia Giannini, Natalie Florescu, Fabian Peisker, Amy Ko, Emily A. Rosen, Javier Perales-Patón, Edwin Chen, Nouran S. Abdelfattah, Shannon Elf
Supplementary Data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::225b3d2075451903b5fcff9e4c3c0a7f
https://doi.org/10.1158/2159-8290.22531497.v1
https://doi.org/10.1158/2159-8290.22531497.v1
Autor:
Ann Mullally, Fatima Al-Shahrour, Rebekka K. Schneider, Julie-Aurore Losman, Zuzana Tothova, Elizabeth A. Morgan, Ofir Wolach, Silvia Giannini, Natalie Florescu, Fabian Peisker, Amy Ko, Emily A. Rosen, Javier Perales-Patón, Edwin Chen, Nouran S. Abdelfattah, Shannon Elf
Supplementary Figure S5. Immunoblotting of Calr-immunoprecipitated proteins and whole cell lysates from Ba/F3-Cas9 and Ba/F3-MPL-Cas9 cells targeted with Calr-directed CRISPR gene editing using a control guide, Calr guide m1, or Calr guide m2 demonst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c11696894dc67ffc41e435b2f774eb4
https://doi.org/10.1158/2159-8290.22531500
https://doi.org/10.1158/2159-8290.22531500
Autor:
Kang Le, Xunde Wang, Maureen Lundt, Anna Conrey, Ingrid Frey, Silvia Giannini, Penelope A. Kosinski, John A. Hausman, Philip S. Low, Neal Jeffries, Swee Lay Thein
Publikováno v:
Blood. 140:5395-5396