Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Silvia G Vaena"'
Autor:
Raquela J Thomas, Natalia Oleinik, Shanmugam Panneer Selvam, Silvia G Vaena, Mohammed Dany, Rose N Nganga, Ryan Depalma, Kyla D Baron, Jisun Kim, Zdzislaw M Szulc, Besim Ogretmen
Publikováno v:
EMBO Molecular Medicine, Vol 9, Iss 8, Pp 1030-1051 (2017)
Abstract Human papillomavirus (HPV) infection is linked to improved survival in response to chemo‐radiotherapy for patients with oropharynx head and neck squamous cell carcinoma (HNSCC). However, mechanisms involved in increased HNSCC cell death by
Externí odkaz:
https://doaj.org/article/7013a186fb3a4ded904c2d03d5e097fa
Autor:
Paramita Chakraborty, Silvia G. Vaena, Krishnamurthy Thyagarajan, Shilpak Chatterjee, Amir Al-Khami, Shanmugam Panneer Selvam, Hung Nguyen, Inhong Kang, Megan W. Wyatt, Uday Baliga, Zachariah Hedley, Rose N. Ngang, Beichu Guo, Gyda C. Beeson, Shahid Husain, Chrystal M. Paulos, Craig C. Beeson, Michael J. Zilliox, Elizabeth G. Hill, Meenal Mehrotra, Xue-Zhong Yu, Besim Ogretmen, Shikhar Mehrotra
Publikováno v:
Cell Reports, Vol 28, Iss 7, Pp 1879-1893.e7 (2019)
Summary: Sphingosine 1-phosphate (S1P), a bioactive lysophospholipid generated by sphingosine kinase 1 (SphK1), regulates lymphocyte egress into circulation via S1P receptor 1 (S1PR1) signaling, and it controls the differentiation of regulatory T cel
Externí odkaz:
https://doaj.org/article/7f8c2775b7694880b2a02c17a884d38d
Autor:
Nathan McChesney, Jeremy L. Barth, Jeffrey A. Rumschlag, Junying Tan, Adam J. Harrington, Kenyaria V. Noble, Carolyn M. McClaskey, Phillip Elvis, Silvia G. Vaena, Martin J. Romeo, Kelly C. Harris, Christopher W. Cowan, Hainan Lang
Publikováno v:
J Neurosci
Dysfunction of the peripheral auditory nerve (AN) contributes to dynamic changes throughout the central auditory system, resulting in abnormal auditory processing, including hypersensitivity. Altered sound sensitivity is frequently observed in autism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::701aa7dab8c6c507c2f7a1d8feb10a80
https://pubmed.ncbi.nlm.nih.gov/36180228
https://pubmed.ncbi.nlm.nih.gov/36180228
Autor:
Alhaji H Janneh, Hong Li, Zachariah Hedley, Xue-Zhong Yu, Mohamed Faisal Kassir, Shikhar Mehrotra, Robert V. Stahelin, Besim Ogretmen, M. Hanief Sofi, Gyda C. Beeson, Paramita Chakraborty, Ahmet Yalcinkaya, Monica L. Husby, Silvia G. Vaena, Han Gyul Lee
Publikováno v:
Cell Reports, Vol 35, Iss 5, Pp 109076-(2021)
Cell reports
Cell reports
SUMMARY We lack a mechanistic understanding of aging-mediated changes in mitochondrial bioenergetics and lipid metabolism that affect T cell function. The bioactive sphingolipid ceramide, induced by aging stress, mediates mitophagy and cell death; ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e766caf701f080dd29045e0fb651782
http://www.sciencedirect.com/science/article/pii/S2211124721004071
http://www.sciencedirect.com/science/article/pii/S2211124721004071
Autor:
Jisun Kim, Raquela J. Thomas, Kyla D. Baron, Ryan M DePalma, Silvia G. Vaena, Rose Nganga, Natalia V. Oleinik, Zdzislaw M. Szulc, Shanmugam Panneer Selvam, Besim Ogretmen, Mohammed Dany
Publikováno v:
EMBO Molecular Medicine
Human papillomavirus (HPV) infection is linked to improved survival in response to chemo‐radiotherapy for patients with oropharynx head and neck squamous cell carcinoma (HNSCC). However, mechanisms involved in increased HNSCC cell death by HPV sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dadeaf81149f52cba9b8ca8699ec2791
https://pubmed.ncbi.nlm.nih.gov/28606997
https://pubmed.ncbi.nlm.nih.gov/28606997
Autor:
Besim Ogretmen, Shikhar Mehrotra, Rose N. Ngang, Hung Nguyen, Gyda C. Beeson, Paramita Chakraborty, Silvia G. Vaena, Uday K Baliga, Beichu Guo, Meenal Mehrotra, Shahid Husain, Michael J. Zilliox, Krishnamurthy Thyagarajan, Shanmugam Panneer Selvam, In-Hong Kang, Zachariah Hedley, Chrystal M. Paulos, Amir A. Al-Khami, Craig Beeson, Xue-Zhong Yu, Elizabeth G. Hill, Megan W. Wyatt, Shilpak Chatterjee
Publikováno v:
Cell reports
Cell Reports, Vol 28, Iss 7, Pp 1879-1893.e7 (2019)
Cell Reports, Vol 28, Iss 7, Pp 1879-1893.e7 (2019)
SUMMARY Sphingosine 1-phosphate (S1P), a bioactive lysophospholipid generated by sphingosine kinase 1 (SphK1), regulates lymphocyte egress into circulation via S1P receptor 1 (S1PR1) signaling, and it controls the differentiation of regulatory T cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8599b1240d51526fd3b461858c11d6dc
http://europepmc.org/articles/PMC6889821
http://europepmc.org/articles/PMC6889821
Autor:
Dennis K. Watson, E. Ramsay Camp, R. Eric Moretz, Silvia G. Vaena, David T. Marshall, M Ashenafi, Cindy Wang, Victoria J. Findlay, Savannah G. Bandurraga
Publikováno v:
Molecular Carcinogenesis. 53:E130-E139
Recently, a reciprocal relationship between calcitriol and epithelial-to-mesenchymal transition has been described. Therefore, we hypothesized that calcitriol (1α,25-dihydroxyvitamin D3) would enhance radiation sensitivity in colorectal cancer regul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4686931b7a43b8fc0a540a116f2e0e5c
https://doi.org/10.1002/mc.22054
https://doi.org/10.1002/mc.22054
Autor:
Jarret Walsh, Dennis K. Watson, David N. Lewin, Victoria J. Findlay, E. Ramsay Camp, Silvia G. Vaena, David P. Turner
Publikováno v:
Journal of Surgical Research. 170:56-63
Background Epithelial-to-mesenchymal transition (EMT) is a series of molecular changes allowing epithelial cancer cells to acquire properties of mesenchymal cells: increased motility, invasion, and protection from apoptosis. Transcriptional regulator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19c6e0637c696799ac1a3c0be8fb25bd
https://doi.org/10.1016/j.jss.2011.02.012
https://doi.org/10.1016/j.jss.2011.02.012
Publikováno v:
Molecular and Cellular Biochemistry. 258:191-199
We have previously reported that ACTH activates a phospholipase C that hydrolyzes glycosylphosphatidylinositol (GPI), which would release inositolphosphoglycan (IPG) to the extracellular medium, and that an IPG purified from Trypanosoma cruzi is able
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42d348df1cb3cb04ac11c7c02adbbd2a
https://doi.org/10.1023/b:mcbi.0000012855.94291.dd
https://doi.org/10.1023/b:mcbi.0000012855.94291.dd
Autor:
Silvia G. Vaena de Avalos, Michael L. Fisher, Ira J. Blader, John C. Boothroyd, Barbara A. Burleigh
Publikováno v:
Journal of Biological Chemistry. 277:639-644
Host cell infection by the intracellular pathogen, Trypanosoma cruzi, involves activation of signaling pathways, cytoskeletal reorganization, and targeted recruitment of host cell lysosomes. To determine the consequences of T. cruzi invasion on host
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1468543cc24ff847c7e5d69dc340356
https://doi.org/10.1074/jbc.m109037200
https://doi.org/10.1074/jbc.m109037200