Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Silvia Frutos"'
Autor:
Rob C. Oslund, Tamara Reyes-Robles, Cory H. White, Jake H. Tomlinson, Kelly A. Crotty, Edward P. Bowman, Dan Chang, Vanessa M. Peterson, Lixia Li, Silvia Frutos, Miquel Vila-Perelló, David Vlerick, Karen Cromie, David H. Perlman, Sampat Ingale, Samantha D. O’ Hara, Lee R. Roberts, Grazia Piizzi, Erik C. Hett, Daria J. Hazuda, Olugbeminiyi O. Fadeyi
Publikováno v:
Nature Chemical Biology. 18:850-858
Autor:
Marco Cavaco, Silvia Frutos, David Andreu, Miquel Vila-Perelló, Vera Neves, Paula Oliete, Javier Valle, Miguel A. R. B. Castanho
Publikováno v:
ACS Medicinal Chemistry Letters. 12:1663-1668
© 2021 The Authors. Published by American Chemical Society
The frequency of brain disease has increased significantly in the past years. After diagnosis, therapeutic options are usually limited, which demands the development of innovative thera
The frequency of brain disease has increased significantly in the past years. After diagnosis, therapeutic options are usually limited, which demands the development of innovative thera
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Understanding how proteins fold into their native structure is a fundamental problem in biophysics, crucial for protein design. It has been hypothesized that the formation of a molten globule intermediate precedes folding to the native conformation o
Autor:
Oscar G. Barbosa, Graciela Mingo, Rodolfo Grippo, Silvia Frutos, Edgar Reziale, Andrés Gamarci, Fernando Corvoisier
Publikováno v:
Ciencia, Docencia y Tecnología, Vol 19, Iss 36, Pp 121-148 (2008)
Se analiza la relación entre desempleo, pobreza, economía social y desarrollo local. Se sostiene que para superar los niveles de subsistencia, se requiere insertar las iniciativas cooperarias en un sistema de economía del trabajo articulado y avan
Externí odkaz:
https://doaj.org/article/c5607892f21e4ea3a717321c41bb8e8d
Autor:
Grazia Piizzi, Karen Cromie, Samantha D. O’Hara, Rob C. Oslund, Kelly A. Crotty, Vanessa M. Peterson, Lee R. Roberts, Daria J. Hazuda, Cory H. White, Erik C. Hett, Tamara Reyes-Robles, David H. Perlman, Dan Chang, David Vlerick, Silvia Frutos, Olugbeminiyi O. Fadeyi, Edward P. Bowman, Jake H. Tomlinson, Miquel Vila-Perelló, Lixia Li
Cell-cell interactions drive essential biological processes critical to cell and tissue development, function, pathology, and disease outcome. The growing appreciation of immune cell interactions within disease environments has led to significant eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be94bbf6f8e3c3e1350c37ea44680a31
https://doi.org/10.1101/2021.10.04.463039
https://doi.org/10.1101/2021.10.04.463039
Autor:
Silvia, Frutos
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2133
Protein semisynthesis is a powerful tool for studying proteins and has contributed to a better understanding of protein structure and function and also driven innovations in protein science. Expressed protein ligation (EPL) is a widely used method to
Autor:
Silvia Frutos
Publikováno v:
Expressed Protein Ligation ISBN: 9781071604335
Protein semisynthesis is a powerful tool for studying proteins and has contributed to a better understanding of protein structure and function and also driven innovations in protein science. Expressed protein ligation (EPL) is a widely used method to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e773ff6384d8ecec78019ab7b9b585a6
https://doi.org/10.1007/978-1-0716-0434-2_9
https://doi.org/10.1007/978-1-0716-0434-2_9
Publikováno v:
Organic & Biomolecular Chemistry. 14:9549-9553
An ideal drug should be highly effective, non-toxic and be delivered by a convenient and painless single dose. We are still far from such optimal treatment but peptides, with their high target selectivity and low toxicity profiles, provide a very att
Autor:
Carme Calvis, Silvia Frutos, Jaume Adan, Anabel Otero, José L. Hernández, Francesc Mitjans, Miquel Vila-Perelló
Publikováno v:
Bioconjugate chemistry. 29(11)
Antibody-Drug Conjugates (ADCs) have been shown to produce clinical benefit in cancer patient thanks to their ability to target highly cytotoxic small molecules to tumor cells. However, the development of these complex molecules faces significant cha
Autor:
Galia T. Debelouchina, Matthew J. Bick, Miquel Vila-Perelló, Zhihua Liu, Seth A. Darst, Silvia Frutos, Tom W. Muir
Publikováno v:
Proceedings of the National Academy of Sciences. 111:8422-8427
Inteins are autoprocessing domains that cut themselves out of host proteins in a traceless manner. This process, known as protein splicing, involves multiple chemical steps that must be coordinated to ensure fidelity in the process. The committed ste