Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Silvia Fischer"'
Publikováno v:
Journal of Biomedical Science, Vol 30, Iss 1, Pp 1-50 (2023)
Abstract Neurological disorders such as stroke, multiple sclerosis, as well as the neurodegenerative diseases Parkinson's or Alzheimer's disease are accompanied or even powered by danger associated molecular patterns (DAMPs), defined as endogenous mo
Externí odkaz:
https://doaj.org/article/a59c18679bc040ea8e7b881da8bca058
Autor:
Silvia Fischer, Emil Nasyrov, Monika Brosien, Klaus T. Preissner, Hugo H. Marti, Reiner Kunze
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-13 (2021)
Abstract Objective Astrocytes participate in the local innate immune response of the central nervous system. In response to stress such as ischemia, activated cells release endogenous factors known as damage-associated molecular patterns (DAMPs). Sel
Externí odkaz:
https://doaj.org/article/0caa6a0917ab42cbacfdd3aca7802f56
Autor:
Anton Früh, Katharina Tielking, Felix Schoknecht, Shuheng Liu, Ulf C. Schneider, Silvia Fischer, Peter Vajkoczy, Ran Xu
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Background: Subarachnoid hemorrhage (SAH) caused by rupture of an intracranial aneurysm, is a life-threatening emergency that is associated with substantial morbidity and mortality. Emerging evidence suggests involvement of the innate immune response
Externí odkaz:
https://doaj.org/article/ef33db81546542e58a8df2060127ab02
Autor:
Silvia Fischer, Elisabeth Deindl
Publikováno v:
Cells, Vol 11, Iss 17, p 2705 (2022)
The innate immune system is the first line of defense against bacterial and viral infections and sterile inflammation through the recognition of pathogen-associated molecular patterns (PAMPs) as well as danger-associated molecular patterns (DAMPs) by
Externí odkaz:
https://doaj.org/article/d2e918413a8f4036a6115080a8634a21
Autor:
Karsten Grote, Marina Nicolai, Uwe Schubert, Bernhard Schieffer, Christian Troidl, Klaus T. Preissner, Stefan Bauer, Silvia Fischer
Publikováno v:
Cells, Vol 11, Iss 9, p 1440 (2022)
Self-extracellular RNA (eRNA), which is released under pathological conditions from damaged tissue, has recently been identified as a new alarmin and synergistic agent together with toll-like receptor (TLR)2 ligands to induce proinflammatory activiti
Externí odkaz:
https://doaj.org/article/fe007447e3ff4d5e90ce0863e0c0cca5
Autor:
Sebastian Strubl, Uwe Schubert, Andrea Kühnle, Alexander Rebl, Negah Ahmadvand, Silvia Fischer, Klaus T. Preissner, Sebastian P. Galuska
Publikováno v:
Cell & Bioscience, Vol 8, Iss 1, Pp 1-9 (2018)
Abstract Background Sialic acids represent common terminal residues on numerous mammalian glycoconjugates, thereby influencing e.g. lumen formation in developing blood vessels. Interestingly, besides monosialylated also polysialylated glycoconjugates
Externí odkaz:
https://doaj.org/article/d193c312727b4b15ae95bce8147d42b9
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Upon vascular injury, tissue damage, ischemia, or microbial infection, intracellular material such as nucleic acids and histones is liberated and comes into contact with the vessel wall and circulating blood cells. Such “Danger-associated molecular
Externí odkaz:
https://doaj.org/article/582b232336164cb7a1c7d10de9620396
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
The discovery of extracellular RNA (exRNA) has shifted our understanding of the role of RNA in complex cellular functions such as cell-to-cell communication and a variety of pathologies. ExRNAs constitute a heterogenous group of RNAs ranging from sma
Externí odkaz:
https://doaj.org/article/e98d4a4039d944f9b82a3b0c01e217dd
Autor:
Silvia Fischer, Elisabeth Deindl
Publikováno v:
Applied Sciences, Vol 11, Iss 16, p 7520 (2021)
Extracellular vesicles (EVs) are important players in the communication between different kinds of cells by delivering their content, consisting of different types of RNA, proteins, bioactive lipids, or signaling nucleotides, into their target cells.
Externí odkaz:
https://doaj.org/article/90c04ca80d3f472bba15cdfe86e2fce7
Autor:
Matthias Kübler, Sebastian Beck, Lisa Lilian Peffenköver, Philipp Götz, Hellen Ishikawa-Ankerhold, Klaus T. Preissner, Silvia Fischer, Manuel Lasch, Elisabeth Deindl
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 17, p 9484 (2021)
Extracellular Cold-inducible RNA-binding protein (eCIRP), a damage-associated molecular pattern, is released from cells upon hypoxia and cold-stress. The overall absence of extra- and intracellular CIRP is associated with increased angiogenesis, most
Externí odkaz:
https://doaj.org/article/bf1e747dce5141d0a2f8e6c7df6cc386