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of 16
pro vyhledávání: '"Silvia Fenoglio"'
Autor:
Michael T. Hemann, Douglas A. Lauffenburger, Matthew G. Vander Heiden, Jacqueline A. Lees, Alba Luengo, Silvia Fenoglio, Emanuel Kreidl, Helen S. Mueller, Beatrice Grauman-Boss, Allison N. Lau, Mark R. Sullivan, Simona Dalin
Fig. S3. Absolute quantification of the indicated species in 3 day CM. (A-D) 8-MDP and dipyridamole were applied to PSC2s conditioning the media at 6.67 uM. A83 was applied to PSC2s conditioning the media at 5 uM. Data show 3 biological replicates +/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::254af58046c2036fbcbe8c88184f11ad
https://doi.org/10.1158/0008-5472.22422684.v1
https://doi.org/10.1158/0008-5472.22422684.v1
Autor:
Michael T. Hemann, Douglas A. Lauffenburger, Matthew G. Vander Heiden, Jacqueline A. Lees, Alba Luengo, Silvia Fenoglio, Emanuel Kreidl, Helen S. Mueller, Beatrice Grauman-Boss, Allison N. Lau, Mark R. Sullivan, Simona Dalin
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::038c2de338264132cbea7e1550b76895
https://doi.org/10.1158/0008-5472.22422672.v1
https://doi.org/10.1158/0008-5472.22422672.v1
Autor:
Michael T. Hemann, Douglas A. Lauffenburger, Matthew G. Vander Heiden, Jacqueline A. Lees, Alba Luengo, Silvia Fenoglio, Emanuel Kreidl, Helen S. Mueller, Beatrice Grauman-Boss, Allison N. Lau, Mark R. Sullivan, Simona Dalin
Pancreatic ductal adenocarcinoma (PDAC) is a leading cause of cancer deaths in the United States. The deoxynucleoside analogue gemcitabine is among the most effective therapies to treat PDAC, however, nearly all patients treated with gemcitabine eith
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70801551aa588cb330d515797b2a52b3
https://doi.org/10.1158/0008-5472.c.6511311.v1
https://doi.org/10.1158/0008-5472.c.6511311.v1
Autor:
Ashley Choi, Samuel Meier, Silvia Fenoglio, Tianshu Feng, Justin Engel, Binzhang Shen, Shangtao Liu, Teng Teng, Tenzing Khendu, Alan Huang, Jannik Andersen, Xuewen Pan, Yi Yu
Publikováno v:
Cancer Research. 82:1224-1224
CRISPR-based functional genomics screens are a powerful tool for identifying synthetically lethal cancer drug targets. Current strategies for analyzing pooled CRISPR screens usually rely on signals from single guide RNAs (sgRNA) with differential rel
Autor:
Silvia Fenoglio, Aileen M. Cristo, James Tepper, Teng Teng, Samuel R. Meier, Ashley Choi, Hongxiang Zhang, Shan-chuan Zhao, Shangtao Liu, Leanne G. Ahronian, Daniel Aird, Nikitha M. Das, Yi Yu, Robert Tjin Tham Sjin, Jannik N. Andersen, Alan Huang, Fang Li, Xuewen Pan
Publikováno v:
Molecular Cancer Therapeutics. 20:P183-P183
KRAS is the most frequently mutated oncogene in human tumors and drives tumorigenesis across multiple lineages. Specifically, KRAS is mutated in about 30% of lung cancer and over 90% of pancreatic cancer. Despite recent progress in developing mutant
Autor:
Douglas A. Lauffenburger, Helen S. Mueller, Jacqueline A. Lees, Allison N. Lau, Mark R. Sullivan, Emanuel Kreidl, Simona Dalin, Beatrice Grauman-Boss, Michael T. Hemann, Matthew G. Vander Heiden, Alba Luengo, Silvia Fenoglio
Publikováno v:
Cancer Res
Pancreatic ductal adenocarcinoma (PDAC) is a leading cause of cancer deaths in the United States. The deoxynucleoside analogue gemcitabine is among the most effective therapies to treat PDAC, however, nearly all patients treated with gemcitabine eith
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ea1fd3381ff9d9c18cd135c7954b136
https://europepmc.org/articles/PMC7357734/
https://europepmc.org/articles/PMC7357734/
Autor:
Allison N. Lau, Michael T. Hemann, Matthew G. Vander Heiden, Emanuel Kreidl, Mark R. Sullivan, Simona Dalin, Beatrice Grauman-Boss, Douglas A. Lauffenburger, Silvia Fenoglio, Alba Luengo
Pancreatic ductal adenocarcinoma (PDAC) is a leading cause of cancer deaths in the United States. The deoxynucleoside analog gemcitabine is among the most effective therapies to treat PDAC; however, nearly all patients treated with gemcitabine either
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73b5b8a6c64ec0f0b73b1c8dfc696d18
Akademický článek
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Autor:
Annalisa Petrelli, Paola Circosta, Silvia Giordano, Massimiliano Mazzone, Luisa Granziero, Silvia Fenoglio, Alberto Pisacane, Paolo M. Comoglio
Publikováno v:
Proceedings of the National Academy of Sciences
Targeting tyrosine kinase receptors (RTKs) with specific Abs is a promising therapeutic approach for cancer treatment, although the molecular mechanism(s) responsible for the Abs’ biological activity are not completely known. We targeted the transm
Autor:
Assaf Gordon, Silvia Fenoglio, Felix Muerdter, Darryl J. Pappin, Astrid D. Haase, Caifu Chen, Gregory J. Hannon, Paloma M. Guzzardo, Benjamin Czech
Publikováno v:
Genesdevelopment. 24(22)
Combining RNAi in cultured cells and analysis of mutant animals, we probed the roles of known Piwi-interacting RNA (piRNA) pathway components in the initiation and effector phases of transposon silencing. Squash associated physically with Piwi, and r