Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Silvia Crasto"'
Autor:
Carlotta Ronchi, Camilla Galli, Gabriele Tullii, Camilla Marzuoli, Marta Mazzola, Marco Malferrari, Silvia Crasto, Stefania Rapino, Elisa Di Pasquale, Maria Rosa Antognazza
Publikováno v:
Advanced Science, Vol 11, Iss 3, Pp n/a-n/a (2024)
Abstract Optical stimulation in the red/near infrared range recently gained increasing interest, as a not‐invasive tool to control cardiac cell activity and repair in disease conditions. Translation of this approach to therapy is hampered by scarce
Externí odkaz:
https://doaj.org/article/8bb4ec847c0f4a9d9700bc789c285ac0
Autor:
Caroline Le Dour, Maria Chatzifrangkeskou, Coline Macquart, Maria M. Magiera, Cécile Peccate, Charlène Jouve, Laura Virtanen, Tiina Heliö, Katriina Aalto-Setälä, Silvia Crasto, Bruno Cadot, Déborah Cardoso, Nathalie Mougenot, Daniel Adesse, Elisa Di Pasquale, Jean-Sébastien Hulot, Pekka Taimen, Carsten Janke, Antoine Muchir
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
Lamin A/C gene mutations cause dilated cardiomyopathy associated with cofilin-1 phosphorylation and actin destabilization. Here, the authors show that phosphorylated cofilin-1 blunts the MRTF-A/SRF axis, leading to decreased tubulin acetylation and a
Externí odkaz:
https://doaj.org/article/ef932080f9164edd9c93891a4153a646
Autor:
Vito Vurro, Beatrice Federici, Carlotta Ronchi, Chiara Florindi, Valentina Sesti, Silvia Crasto, Claudia Maniezzi, Camilla Galli, Maria Rosa Antognazza, Chiara Bertarelli, Elisa Di Pasquale, Guglielmo Lanzani, Francesco Lodola
Publikováno v:
iScience, Vol 26, Iss 3, Pp 106121- (2023)
Summary: Non-genetic photostimulation is a novel and rapidly growing multidisciplinary field that aims to induce light-sensitivity in living systems by exploiting exogeneous phototransducers. Here, we propose an intramembrane photoswitch, based on an
Externí odkaz:
https://doaj.org/article/e86b3f49a0c145af89f1220bfa25da7d
Autor:
Nicolò Salvarani, Silvia Crasto, Michele Miragoli, Alessandro Bertero, Marianna Paulis, Paolo Kunderfranco, Simone Serio, Alberto Forni, Carla Lucarelli, Matteo Dal Ferro, Veronica Larcher, Gianfranco Sinagra, Paolo Vezzoni, Charles E. Murry, Giuseppe Faggian, Gianluigi Condorelli, Elisa Di Pasquale
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Mutation of LMNA, encoding Lamin A/C nuclear proteins, cause dilated cardiomyopathy and conduction disorders. Here, the authors show that patient-specific iPSC-derived CMs carrying the K219T LMNA mutation have downregulated Nav1.5 channels due to dyn
Externí odkaz:
https://doaj.org/article/975fc60819e84ad6adb18ec63c887d5c
Autor:
Irene Salamon, Simone Serio, Simona Bianco, Christina Pagiatakis, Silvia Crasto, Andrea M. Chiariello, Mattia Conte, Paola Cattaneo, Luca Fiorillo, Arianna Felicetta, Elisa di Pasquale, Paolo Kunderfranco, Mario Nicodemi, Roberto Papait, Gianluigi Condorelli
Publikováno v:
iScience, Vol 23, Iss 9, Pp 101539- (2020)
Summary: Enhancer RNAs (eRNAs) are a subset of long noncoding RNA generated from genomic enhancers: they are thought to act as potent promoters of the expression of nearby genes through interaction with the transcriptional and epigenomic machineries.
Externí odkaz:
https://doaj.org/article/1c45108cf33d43c585a27b5c9e5e722c
Autor:
Kseniya Perepelina, Aleksandra Kostina, Polina Klauzen, Aleksandr Khudiakov, Martina Rabino, Silvia Crasto, Anna Zlotina, Yulia Fomicheva, Alexey Sergushichev, Mari Oganesian, Alexander Dmitriev, Anna Kostareva, Elisa Di Pasquale, Anna Malashicheva
Publikováno v:
Stem Cell Research, Vol 47, Iss , Pp 101895- (2020)
Human iPSC lines were generated from peripheral blood mononuclear cells of patient carrying LMNA mutation associated with Emery–Dreifuss muscular dystrophy accompanied by atrioventricular block and paroxysmal atrial fibrillation. Reprogramming fact
Externí odkaz:
https://doaj.org/article/0d6065c7037b4bb8bd8548e7f36f3fd1
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Mutations of Lamin A/C gene (LMNA) cause laminopathies, a group of disorders associated with a wide spectrum of clinically distinct phenotypes, affecting different tissues and organs. Heart involvement is frequent and leads to cardiolaminopathy LMNA-
Externí odkaz:
https://doaj.org/article/3d65802e9d0c432389910c5e0c9471eb
Autor:
Silvia Crasto, Elisa Di Pasquale
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 6 (2018)
Laminopathies are a group of rare degenerative disorders that manifest with a wide spectrum of clinical phenotypes, including both systemic multi-organ disorders, such as the Hutchinson-Gilford Progeria Syndrome (HGPS), and tissue-restricted diseases
Externí odkaz:
https://doaj.org/article/d401fccee1f64e1cb088baceee243a6f
Akademický článek
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Autor:
Vito Vurro, Beatrice Federici, Carlotta Ronchi, Chiara Florindi, Valentina Sesti, Silvia Crasto, Claudia Maniezzi, Camilla Galli, Maria Rosa Antognazza, Chiara Bertarelli, Elisa Di Pasquale, Guglielmo Lanzani, Francesco Lodola
Non-genetic photostimulation is a novel and rapidly growing multidisciplinary field of research that aims to induce light sensitivity in living systems by exploiting exogeneous phototransducers.Here we propose a recently synthetized intramembrane pho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3af7b1b5f9f37576e526f79ed58d8cff
https://doi.org/10.1101/2022.09.22.508828
https://doi.org/10.1101/2022.09.22.508828