Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Silvia Coma"'
Autor:
Tobias Max Philipp Hartwich, Miranda Mansolf, Cem Demirkiran, Michelle Greenman, Stefania Bellone, Blair McNamara, Shuvro P. Nandi, Ludmil B. Alexandrov, Yang Yang‐Hartwich, Silvia Coma, Jonathan Pachter, Alessandro D. Santin
Publikováno v:
Cancer Medicine, Vol 13, Iss 17, Pp n/a-n/a (2024)
Abstract Background High‐grade endometrial cancers (EAC) are aggressive tumors with a high risk of progression after treatment. As EAC may harbor mutations in the RAS/MAPK pathways, we evaluated the preclinical in vitro and in vivo efficacy of avut
Externí odkaz:
https://doaj.org/article/c903116f7e7848cf816112aa15bc9253
Autor:
Kathleen J. Till, Mariah Abdullah, Tahera Alnassfan, Gallardo Zapata Janet, Thomas Marks, Silvia Coma, David T. Weaver, Jonathan A. Pachter, Andrew R. Pettitt, Joseph R. Slupsky
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Mantle cell lymphoma (MCL) is an aggressive B-cell non-Hodgkin lymphoma that is incurable with existing therapies, and therefore presents a significant unmet clinical need. The ability of this disease to overcome therapy, including those tha
Externí odkaz:
https://doaj.org/article/4cff650fc4244e77b75d4ef75a467df3
Therapeutic targeting of tumor growth and angiogenesis with a novel anti-S100A4 monoclonal antibody.
Autor:
Jose Luis Hernández, Laura Padilla, Sheila Dakhel, Toni Coll, Rosa Hervas, Jaume Adan, Marc Masa, Francesc Mitjans, Josep Maria Martinez, Silvia Coma, Laura Rodríguez, Véronique Noé, Carlos J Ciudad, Francesc Blasco, Ramon Messeguer
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e72480 (2013)
S100A4, a member of the S100 calcium-binding protein family secreted by tumor and stromal cells, supports tumorigenesis by stimulating angiogenesis. We demonstrated that S100A4 synergizes with vascular endothelial growth factor (VEGF), via the RAGE r
Externí odkaz:
https://doaj.org/article/23454e4cdb4f4dd6a2efcfad043f89b4
Autor:
Hanwen Zhang, Shuhua Wang, Manali Rupji, Chenxi Wu, Sanjay Chandrasekaran, Christopher R. Funk, Patrick J. King, Saketh Kollipara, Ishani Rao, Esohe Ayanru, Julia Duffy, Roberta Kaplow, Aseala Abousaud, Aneesh Mehta, John D. Roback, Daniel Kalman, G. Marshall Lyon, Mark Caridi-Scheible, Gregory Bisson, Yuan Liu, Silvia Coma, Jonathan A. Pachter, Cynthia R. Giver, Edmund K. Waller
Publikováno v:
Blood. 140:11187-11189
Autor:
Jeffrey Ecsedy, Xiaoyan M. Zhang, Mark Manfredi, Prabitha Natarajan, Sakeena Syed, Jeremy Tchaicha, Meghan Walsh, Silvia Coma, Jill Cavanaugh, Alfredo C. Castro, Karen McGovern
Supplementary Table from Discovery and Characterization of a Novel Aryl Hydrocarbon Receptor Inhibitor, IK-175, and Its Inhibitory Activity on Tumor Immune Suppression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08a11276840ac47ab69018568d15800d
https://doi.org/10.1158/1535-7163.22523289.v1
https://doi.org/10.1158/1535-7163.22523289.v1
Autor:
Jeffrey Ecsedy, Xiaoyan M. Zhang, Mark Manfredi, Prabitha Natarajan, Sakeena Syed, Jeremy Tchaicha, Meghan Walsh, Silvia Coma, Jill Cavanaugh, Alfredo C. Castro, Karen McGovern
Supplementary Figure from Discovery and Characterization of a Novel Aryl Hydrocarbon Receptor Inhibitor, IK-175, and Its Inhibitory Activity on Tumor Immune Suppression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::050525c3bfe144ac014dd2f1d4357a1f
https://doi.org/10.1158/1535-7163.22523295.v1
https://doi.org/10.1158/1535-7163.22523295.v1
Autor:
J. Silvio Gutkind, Andrew E. Aplin, Takami Sato, Jonathan A. Pachter, Prashant Mali, Glenn Merlino, Chi-Ping Day, Kyle Ford, Xingyu Wu, Silvia Coma, Manoela Tiago, Nadia Arang, Frederico Gomes, Simone Lubrano, Ayush Kishore, Robert Saddawi-Konefka, Monica Acosta, Justine S. Paradis
Supplementary Figure S4. MEKi/FAKi combination reduces B2905 syngeneic cells growth in allograft tumor models.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::376bd239a291230f0640602beebf5692
https://doi.org/10.1158/1078-0432.22478109
https://doi.org/10.1158/1078-0432.22478109
Autor:
J. Silvio Gutkind, Andrew E. Aplin, Takami Sato, Jonathan A. Pachter, Prashant Mali, Glenn Merlino, Chi-Ping Day, Kyle Ford, Xingyu Wu, Silvia Coma, Manoela Tiago, Nadia Arang, Frederico Gomes, Simone Lubrano, Ayush Kishore, Robert Saddawi-Konefka, Monica Acosta, Justine S. Paradis
Purpose:Uveal melanoma is the most common eye cancer in adults. Approximately 50% of patients with uveal melanoma develop metastatic uveal melanoma (mUM) in the liver, even after successful treatment of the primary lesions. mUM is refractory to curre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6586666443c72d8c7650610b8c2c2ce1
https://doi.org/10.1158/1078-0432.c.6529851
https://doi.org/10.1158/1078-0432.c.6529851
Autor:
J. Silvio Gutkind, Andrew E. Aplin, Takami Sato, Jonathan A. Pachter, Prashant Mali, Glenn Merlino, Chi-Ping Day, Kyle Ford, Xingyu Wu, Silvia Coma, Manoela Tiago, Nadia Arang, Frederico Gomes, Simone Lubrano, Ayush Kishore, Robert Saddawi-Konefka, Monica Acosta, Justine S. Paradis
Supplementary figure S2. Isobologram analysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::488c894c5197a73ee3e502e59c68a8e5
https://doi.org/10.1158/1078-0432.22478115.v1
https://doi.org/10.1158/1078-0432.22478115.v1
Autor:
J. Silvio Gutkind, Andrew E. Aplin, Takami Sato, Jonathan A. Pachter, Prashant Mali, Glenn Merlino, Chi-Ping Day, Kyle Ford, Xingyu Wu, Silvia Coma, Manoela Tiago, Nadia Arang, Frederico Gomes, Simone Lubrano, Ayush Kishore, Robert Saddawi-Konefka, Monica Acosta, Justine S. Paradis
Supplementary figure S1. Synthetic lethality of FAK and ERK/MAPK pathway inhibition.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a403519c803d895983e8ab05e66b7d8
https://doi.org/10.1158/1078-0432.22478118.v1
https://doi.org/10.1158/1078-0432.22478118.v1