Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Silvia Catuogno"'
Autor:
Maria L. Ibba, Giuseppe Ciccone, Deborah Rotoli, Gabriele Coppola, Alfonso Fiorelli, Silvia Catuogno, Carla L. Esposito
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 32, Iss , Pp 111-126 (2023)
The identification of new effective therapeutic options for non-small-cell lung cancer (NSCLC) represents a crucial challenge in oncology. Recent studies indicate that cancer-associated fibroblasts (CAFs) participate in tumor progression by establish
Externí odkaz:
https://doaj.org/article/355f7b2b64c748fa9e32d04320a16a88
Autor:
Carla L. Esposito, Ida Autiero, Annamaria Sandomenico, H. Li, Mahmoud A. Bassal, Maria L. Ibba, Dongfang Wang, Lucrezia Rinaldi, Simone Ummarino, Giulia Gaggi, Marta Borchiellini, Piotr Swiderski, Menotti Ruvo, Silvia Catuogno, Alexander K. Ebralidze, Marcin Kortylewski, Vittorio de Franciscis, Annalisa Di Ruscio
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Here the authors generate an RNA-based platform to neutralize the major epigenetic player DNMT1. Using this targeted approach, aberrant DNA methylation in cancer can be corrected.
Externí odkaz:
https://doaj.org/article/1ac7b00822ad42efaffe5d498c64c726
Autor:
Silvia Nuzzo, Margherita Iaboni, Maria Luigia Ibba, Anna Rienzo, Domenica Musumeci, Monica Franzese, Giuseppina Roscigno, Alessandra Affinito, Gianluca Petrillo, Cristina Quintavalle, Giuseppe Ciccone, Carla Lucia Esposito, Silvia Catuogno
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Hypoxia plays a crucial role in tumorigenesis and drug resistance, and it is recognised as a major factor affecting patient clinical outcome. Therefore, the detection of hypoxic areas within the tumour micro-environment represents a useful way to mon
Externí odkaz:
https://doaj.org/article/574150afabb14c51833f312d2ef186ac
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6121 (2023)
Non-small-cell lung cancer (NSCLC) is the second most diagnosed type of malignancy and the first cause of cancer death worldwide. Despite recent advances, the treatment of choice for NSCLC patients remains to be chemotherapy, often showing very limit
Externí odkaz:
https://doaj.org/article/7f73be32b9174646bd60460e409e1779
Autor:
Carla Lucia Esposito, Cristina Quintavalle, Francesco Ingenito, Deborah Rotoli, Giuseppina Roscigno, Silvia Nuzzo, Renato Thomas, Silvia Catuogno, Vittorio de Franciscis, Gerolama Condorelli
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 23, Iss , Pp 982-994 (2021)
Breast cancer is a leading cause of cancer mortality in women. Despite advances in its management, the identification of new options for early-stage diagnosis and therapy of this tumor still represents a crucial challenge. Increasing evidence indicat
Externí odkaz:
https://doaj.org/article/c40392047de44fa0975ab4413f89e90d
Autor:
Silvia Catuogno, Maria Teresa Di Martino, Silvia Nuzzo, Carla Lucia Esposito, Pierfrancesco Tassone, Vittorio de Franciscis
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 18, Iss , Pp 981-990 (2019)
B cell maturation antigen is highly expressed on malignant plasma cells in human multiple myeloma and has recently emerged as a very promising target for therapeutic interventions. Nucleic-acid-based aptamers are small oligonucleotides with high sele
Externí odkaz:
https://doaj.org/article/6eacff4f6e0b4359b5b19cd23eba5f0f
Autor:
Silvia Nuzzo, Silvia Catuogno, Maria Capuozzo, Alfonso Fiorelli, Piotr Swiderski, Serena Boccella, Filomena de Nigris, Carla Lucia Esposito
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 17, Iss , Pp 256-263 (2019)
Non-small-cell lung cancer (NSCLC) accounts for 85%–90% of all cases of lung cancer that is the most deadly type of cancer. Despite advances in chemotherapy and radiotherapy, severe side effects and frequent drug resistance limit the success of the
Externí odkaz:
https://doaj.org/article/a85c657154e04d3d8811c3e693d25318
Autor:
Carla Lucia Esposito, Silvia Nuzzo, Silvia Catuogno, Simona Romano, Filomena de Nigris, Vittorio de Franciscis
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 10, Iss , Pp 398-411 (2018)
Glioblastoma (GBM) is the most frequent and aggressive primary brain tumor in adults, and despite advances in neuro-oncology, the prognosis for patients remains dismal. The signal transducer and activator of transcription-3 (STAT3) has been reported
Externí odkaz:
https://doaj.org/article/4282b9f693a6471598054e72cc554a78
Autor:
Carla L. Esposito, Katrien Van Roosbroeck, Gianluca Santamaria, Deborah Rotoli, Annamaria Sandomenico, William G. Wierda, Alessandra Ferrajoli, Menotti Ruvo, George A. Calin, Vittorio de Franciscis, Silvia Catuogno
Publikováno v:
Cancers, Vol 13, Iss 20, p 5220 (2021)
The transmembrane glycoprotein cluster of differentiation 19 (CD19) is a B cell–specific surface marker, expressed on the majority of neoplastic B cells, and has recently emerged as a very attractive biomarker and therapeutic target for B-cell mali
Externí odkaz:
https://doaj.org/article/bec828a0b55e41e0a65683a2c208977a
Autor:
Pinar Kanlikilicer, Bulent Ozpolat, Burcu Aslan, Recep Bayraktar, Nilgun Gurbuz, Cristian Rodriguez-Aguayo, Emine Bayraktar, Merve Denizli, Vianey Gonzalez-Villasana, Cristina Ivan, Ganesh L.R. Lokesh, Paola Amero, Silvia Catuogno, Monika Haemmerle, Sherry Yen-Yao Wu, Rahul Mitra, David G. Gorenstein, David E. Volk, Vittorio de Franciscis, Anil K. Sood, Gabriel Lopez-Berestein
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 9, Iss C, Pp 251-262 (2017)
Despite substantial improvements in the treatment strategies, ovarian cancer is still the most lethal gynecological malignancy. Identification of drug treatable therapeutic targets and their safe and effective targeting is critical to improve patient
Externí odkaz:
https://doaj.org/article/30d18358dbe6414f995427ef4aed9541