Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Silvia Castrignanò"'
Autor:
Giovanna Di Nardo, Almerinda Di Venere, Chao Zhang, Eleonora Nicolai, Silvia Castrignanò, Luisa Di Paola, Gianfranco Gilardi, Giampiero Mei
Publikováno v:
Biology Direct, Vol 16, Iss 1, Pp 1-12 (2021)
Abstract Human aromatase is a member of the cytochrome P450 superfamily, involved in steroid hormones biosynthesis. In particular, it converts androgen into estrogens being therefore responsible for the correct sex steroids balance. Due to its capaci
Externí odkaz:
https://doaj.org/article/b195a47b31ca48eba9dac091316f4dda
Autor:
Gianluca Catucci, Alberto Ciaramella, Giovanna Di Nardo, Chao Zhang, Silvia Castrignanò, Gianfranco Gilardi
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 7, p 3618 (2022)
The cytochrome P450 superfamily are heme-thiolate enzymes able to carry out monooxygenase reactions. Several studies have demonstrated the feasibility of using a soluble bacterial reductase from Bacillus megaterium, BMR, as an artificial electron tra
Externí odkaz:
https://doaj.org/article/a0ae331b2fb14938a186535f25678b6e
Autor:
Giovanna Di Nardo, Maximilian Breitner, Sheila J Sadeghi, Silvia Castrignanò, Giampiero Mei, Almerinda Di Venere, Eleonora Nicolai, Paola Allegra, Gianfranco Gilardi
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82118 (2013)
Human aromatase (CYP19A1) is a steroidogenic cytochrome P450 converting androgens into estrogens. No ligand-free crystal structure of the enzyme is available to date. The crystal structure in complex with the substrate androstenedione and the steroid
Externí odkaz:
https://doaj.org/article/39667380175d44a1aec1fd663af13f11
Autor:
Gianluca Catucci, Alberto Ciaramella, Giovanna Di Nardo, Chao Zhang, Silvia Castrignanò, Gianfranco Gilardi
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 7; Pages: 3618
The cytochrome P450 superfamily are heme-thiolate enzymes able to carry out monooxygenase reactions. Several studies have demonstrated the feasibility of using a soluble bacterial reductase from Bacillus megaterium, BMR, as an artificial electron tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::239a13ade24147e1f9c860b33567308b
https://pubmed.ncbi.nlm.nih.gov/35408976
https://pubmed.ncbi.nlm.nih.gov/35408976
Autor:
Eleonora Nicolai, Silvia Castrignanò, Gianfranco Gilardi, Chao Zhang, Giampiero Mei, Giovanna Di Nardo, Almerinda Di Venere, Luisa Di Paola
Publikováno v:
Biology Direct
Biology Direct, Vol 16, Iss 1, Pp 1-12 (2021)
Biology Direct, Vol 16, Iss 1, Pp 1-12 (2021)
Human aromatase is a member of the cytochrome P450 superfamily, involved in steroid hormones biosynthesis. In particular, it converts androgen into estrogens being therefore responsible for the correct sex steroids balance. Due to its capacity in pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f360fb2dfb3f59d659d47d20cf597f49
http://hdl.handle.net/2108/294317
http://hdl.handle.net/2108/294317
Publikováno v:
Bioelectrochemistry (Amsterdam, Netherlands). 138
Polymorphism is an important aspect in drug metabolism responsible for different individual response to drug dosage, often leading to adverse drug reactions. Here human CYP2C9 as well as its polymorphic variants CYP2C9*2 and CYP2C9*3 present in appro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b15647eea3dfea84f16f684754f13445
https://pubmed.ncbi.nlm.nih.gov/33421896
https://pubmed.ncbi.nlm.nih.gov/33421896
Autor:
Sheila J. Sadeghi, Gianfranco Gilardi, Silvia Castrignanò, Giovanna Di Nardo, Serena D'Avino, Gianluca Catucci
Publikováno v:
ORCID
Microsoft Academic Graph
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics
Microsoft Academic Graph
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics
Chimerogenesis involving cytochromes P450 is a successful approach to generate catalytically self-sufficient enzymes. However, the connection between the different functional modules should allow a certain degree of flexibility in order to obtain fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd8d45d089968ca4b59b4e8c050feb7c
https://iris.unito.it/handle/2318/1653483
https://iris.unito.it/handle/2318/1653483
Autor:
Daniela Minerdi, Silvia Castrignanò, Maria Elena Terlizzi, Gianfranco Gilardi, Ivan Zgrablic, Claudio Medana, Giorgio Gribaudo, Gianluca Catucci, Sheila J. Sadeghi
Publikováno v:
Antimicrobial Agents and Chemotherapy. 60:64-74
Antimicrobial resistance is a global issue currently resulting in the deaths of hundreds of thousands of people a year worldwide. Data present in the literature illustrate the emergence of many bacterial species that display resistance to known antib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea4be947d620abfcfd77f07643ce0616
https://doi.org/10.1128/aac.01088-15
https://doi.org/10.1128/aac.01088-15
Publikováno v:
Journal of inorganic biochemistry. 188
The linker region of multi-domain enzymes has a very important role for the interconnection of different enzyme modules and for the efficiency of catalytic activity. This is particularly evident for artificial chimeric systems. We characterised an ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d73cb63259189740ffec1c3e3a5a3043
https://pubmed.ncbi.nlm.nih.gov/30098472
https://pubmed.ncbi.nlm.nih.gov/30098472
Publikováno v:
Biotechnology and Applied Biochemistry. 63:157-162
Glucose oxidase (GOD) was immobilized on glassy carbon electrodes in the presence of graphene oxide (GO) as a model system for the interaction between GO and biological molecules. Lyotropic properties of didodecyldimethylammonium bromide (DDAB) were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c2e0ccee173b1c0451745026b886a8f
https://doi.org/10.1002/bab.1392
https://doi.org/10.1002/bab.1392