Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Silvia C. Teguh"'
Autor:
Thuy G. Le, Yaqing Jiao, Robin B. Gasser, Yuezhou Zhang, Yiyue Xie, Silvia C. Teguh, Min Hu, Aya C Taki, Solomon Tadesse, Jitendra R. Harjani, Sarah Preston, Andreas Hofmann, Jose F. Garcia-Bustos, Swapna Varghese, Jonathan B. Baell, Jephthah O. Odiba, Banfeng Ruan, Abdul Jabbar
Publikováno v:
European journal of medicinal chemistry. 190
Parasitic roundworms (nematodes) are significant pathogens of humans and animals and cause substantive socioeconomic losses due to the diseases that they cause. The control of nematodes in livestock animals relies heavily on the use of anthelmintic d
Autor:
Elizabeth A. Vecchio, Lauren T. May, Jonathan B. Baell, Silvia C. Teguh, Guy Y. Krippner, Ryan Brady, Daniel L. Priebbenow, Chengxue Qin, Julia G. Beveridge, Minh Deo, Rebecca H. Ritchie, Girdhar Singh Deora, Aaron DeBono
Publikováno v:
Journal of medicinal chemistry. 62(10)
Herein we describe the development of a focused series of functionalized pyridazin-3(2 H)-one-based formyl peptide receptor (FPR) agonists that demonstrate high potency and biased agonism. The compounds described demonstrated biased activation of pro