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Autor:
János Tibor Kodra, Cathrine Ørskov, Xiaoai Wu, Steffen Reedtz-Runge, Sif Groth Rønn, Prafull S. Gandhi, Stephanie Hennen, Vladyslav Soroka, Peter Kaastrup, Berit Olsen Krogh, Silvia Barbateskovic, Gerd Schluckebier
Publikováno v:
Scientific Reports
The Glucagon-like peptide-1 receptor (GLP-1R) is a member of the class B G protein-coupled receptor (GPCR) family and a well-established target for the treatment of type 2 diabetes. The N-terminal extracellular domain (ECD) of GLP-1R is important for