Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Silvia Balosso"'
Autor:
Alessia Salamone, Gaetano Terrone, Rossella Di Sapia, Silvia Balosso, Teresa Ravizza, Luca Beltrame, Ilaria Craparotta, Laura Mannarino, Sara Raimondi Cominesi, Massimo Rizzi, Alberto Pauletti, Sergio Marchini, Luca Porcu, Till S. Zimmer, Eleonora Aronica, Matthew During, Brett Abrahams, Shinichi Kondo, Toshiya Nishi, Annamaria Vezzani
Publikováno v:
Neurobiology of Disease, Vol 173, Iss , Pp 105835- (2022)
Therapies for epilepsy mainly provide symptomatic control of seizures since most of the available drugs do not target disease mechanisms. Moreover, about one-third of patients fail to achieve seizure control. To address the clinical need for disease-
Externí odkaz:
https://doaj.org/article/a8d72f20e7364f5fb631d3c581366d20
Autor:
Rossella Di Sapia, Till S. Zimmer, Valentina Kebede, Silvia Balosso, Teresa Ravizza, Diletta Sorrentino, Manuel Alejandro Montano Castillo, Luca Porcu, Franca Cattani, Anna Ruocco, Eleonora Aronica, Marcello Allegretti, Laura Brandolini, Annamaria Vezzani
Publikováno v:
Neurobiology of Disease, Vol 158, Iss , Pp 105468- (2021)
CXCL1, a functional murine orthologue of the human chemokine CXCL8 (IL-8), and its CXCR1 and CXCR2 receptors were investigated in a murine model of acquired epilepsy developing following status epilepticus (SE) induced by intra-amygdala kainate. CXCL
Externí odkaz:
https://doaj.org/article/7325e27ac3f5447aad01b6adc7631f17
Autor:
Jenni Kyyriäinen, Natallie Kajevu, Ivette Bañuelos, Leonardo Lara, Anssi Lipponen, Silvia Balosso, Elina Hämäläinen, Shalini Das Gupta, Noora Puhakka, Teemu Natunen, Teresa Ravizza, Annamaria Vezzani, Mikko Hiltunen, Asla Pitkänen
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 19, p 10555 (2021)
We assessed the effect of antioxidant therapy using the Food and Drug Administration-approved respiratory drug N-acetylcysteine (NAC) or sulforaphane (SFN) as monotherapies or duotherapy in vitro in neuron-BV2 microglial co-cultures and validated the
Externí odkaz:
https://doaj.org/article/b998370c5ed947969d9f9c88922b1f47
Autor:
Jessica Marcon, Barbara Gagliardi, Silvia Balosso, Mattia Maroso, Francesco Noé, Mèlanie Morin, Mireille Lerner-Natoli, Annamaria Vezzani, Teresa Ravizza
Publikováno v:
Neurobiology of Disease, Vol 34, Iss 1, Pp 121-132 (2009)
Brain inflammation, angiogenesis and increased blood-brain barrier (BBB) permeability occur in adult rodent and human epileptogenic brain tissue. We addressed the role of these events in epileptogenesis using a developmental approach since the propen
Externí odkaz:
https://doaj.org/article/55ebd40cde1a4d94851afef2b27ed907
Publikováno v:
Epilepsy & Behavior. 140:109095
Autor:
Teresa Ravizza, Marcello Allegretti, Eleonora Aronica, Diletta Sorrentino, Franca Cattani, Luca Porcu, Silvia Balosso, Manuel Alejandro Montano Castillo, Annamaria Vezzani, Rossella Di Sapia, Valentina Kebede, Anna Ruocco, Laura Brandolini, Till S. Zimmer
Publikováno v:
Neurobiology of Disease, Vol 158, Iss, Pp 105468-(2021)
CXCL1, a functional murine orthologue of the human chemokine CXCL8 (IL-8), and its CXCR1 and CXCR2 receptors were investigated in a murine model of acquired epilepsy developing following status epilepticus (SE) induced by intra-amygdala kainate. CXCL
Publikováno v:
Nature Reviews Neurology. 15:459-472
Epilepsy is a chronic neurological disease characterized by an enduring propensity for generation of seizures. The pathogenic processes of seizure generation and recurrence are the subject of intensive preclinical and clinical investigations as their
Publikováno v:
Inflammation and Epilepsy: New Vistas ISBN: 9783030674021
Unabated neuroinflammation plays a pathogenic role in various CNS diseases. In epilepsy, neuroinflammation is not a bystander phenomenon of the diseased brain but contributes to neuronal hyperexcitability underlying seizure generation, cell loss, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::144c2a6fa772634d9f1fb8040eef1945
https://doi.org/10.1007/978-3-030-67403-8_2
https://doi.org/10.1007/978-3-030-67403-8_2
Neuroinflammation and reactive oxygen and nitrogen species are rapidly induced in the brain after acute cerebral injuries that are associated with an enhanced risk for epilepsy in humans and related animal models. These phenomena reinforce each other
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e0c44f51f6da633645f1804ed6c81b3
http://hdl.handle.net/11588/759305
http://hdl.handle.net/11588/759305
Autor:
Bénédicte Danis, Gregory Szczesny, Silvia Balosso, Catherine Vandenplas, Annamaria Vezzani, Kasper Claes, Jonathan van Eyll, Seon-Ah Chong, Christian Wolff, Xavier Van Damme, Etienne Hanon, Isabelle Niespodziany, Rafal Kaminski
Publikováno v:
Neurotherapeutics
Understanding the mechanisms of epileptogenesis is essential to develop novel drugs that could prevent or modify the disease. Neuroinflammation has been proposed as a promising target for therapeutic interventions to inhibit the epileptogenic process