Zobrazeno 1 - 10
of 162
pro vyhledávání: '"Silvia Bagnoli"'
Autor:
Giulia Giacomucci, Salvatore Mazzeo, Assunta Ingannato, Chiara Crucitti, Silvia Bagnoli, Sonia Padiglioni, Lucrezia Romano, Giulia Galdo, Filippo Emiliani, Daniele Frigerio, Camilla Ferrari, Valentina Moschini, Carmen Morinelli, Antonella Notarelli, Sandro Sorbi, Benedetta Nacmias, Valentina Bessi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract We aimed to assess diagnostic accuracy of plasma p-tau181 and NfL separately and in combination in discriminating Subjective Cognitive Decline (SCD) and Mild Cognitive Impairment (MCI) patients carrying Alzheimer’s Disease (AD) pathology f
Externí odkaz:
https://doaj.org/article/25b5fa92f220479b9fb15d83e5ed0a59
Autor:
Imogen J. Swift, Rosa Rademakers, NiCole Finch, Matt Baker, Roberta Ghidoni, Luisa Benussi, Giuliano Binetti, Giacomina Rossi, Matthis Synofzik, Carlo Wilke, David Mengel, Caroline Graff, Leonel T. Takada, Raquel Sánchez-Valle, Anna Antonell, Daniela Galimberti, Chiara Fenoglio, Maria Serpente, Marina Arcaro, Stefanie Schreiber, Stefan Vielhaber, Philipp Arndt, Isabel Santana, Maria Rosario Almeida, Fermín Moreno, Myriam Barandiaran, Alazne Gabilondo, Johannes Stubert, Estrella Gómez-Tortosa, Pablo Agüero, M. José Sainz, Tomohito Gohda, Maki Murakoshi, Nozomu Kamei, Sarah Kittel-Schneider, Andreas Reif, Johannes Weigl, Jinlong Jian, Chuanju Liu, Ginette Serrero, Thomas Greither, Gerit Theil, Ebba Lohmann, Stefano Gazzina, Silvia Bagnoli, Giovanni Coppola, Amalia Bruni, Mirja Quante, Wieland Kiess, Andreas Hiemisch, Anne Jurkutat, Matthew S. Block, Aaron M. Carlson, Geir Bråthen, Sigrid Botne Sando, Gøril Rolfseng Grøntvedt, Camilla Lauridsen, Amanda Heslegrave, Carolin Heller, Emily Abel, Alba Gómez-Núñez, Roger Puey, Andrea Arighi, Enmanuela Rotondo, Lize C. Jiskoot, Lieke H. H. Meeter, João Durães, Marisa Lima, Miguel Tábuas-Pereira, João Lemos, Bradley Boeve, Ronald C. Petersen, Dennis W. Dickson, Neill R. Graff-Radford, Isabelle LeBer, Leila Sellami, Foudil Lamari, Fabienne Clot, Barbara Borroni, Valentina Cantoni, Jasmine Rivolta, Alberto Lleó, Juan Fortea, Daniel Alcolea, Ignacio Illán-Gala, Lucie Andres-Cerezo, Philip Van Damme, Jordi Clarimon, Petra Steinacker, Emily Feneberg, Markus Otto, Emma L. van der Ende, John C. van Swieten, Harro Seelaar, Henrik Zetterberg, Aitana Sogorb-Esteve, Jonathan D. Rohrer
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-13 (2024)
Abstract Background Pathogenic heterozygous mutations in the progranulin gene (GRN) are a key cause of frontotemporal dementia (FTD), leading to significantly reduced biofluid concentrations of the progranulin protein (PGRN). This has led to a number
Externí odkaz:
https://doaj.org/article/1d7c751ac55c494a90e49ef788756561
Autor:
Alessandra Bigi, Giulia Fani, Valentina Bessi, Liliana Napolitano, Silvia Bagnoli, Assunta Ingannato, Lorenzo Neri, Roberta Cascella, Paolo Matteini, Sandro Sorbi, Benedetta Nacmias, Cristina Cecchi, Fabrizio Chiti
Publikováno v:
Translational Neurodegeneration, Vol 13, Iss 1, Pp 1-5 (2024)
Externí odkaz:
https://doaj.org/article/47ee1919563b4474a43a02c85f006f48
Autor:
Assunta Ingannato, Silvia Bagnoli, Salvatore Mazzeo, Giulia Giacomucci, Valentina Bessi, Camilla Ferrari, Sandro Sorbi, Benedetta Nacmias
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
BackgroundPlasma biomarkers are preferable to invasive and expensive diagnostic tools, such as neuroimaging and lumbar puncture that are gold standard in the clinical management of Alzheimer’s Disease (AD). Here, we investigated plasma Glial Fibril
Externí odkaz:
https://doaj.org/article/06f57d360a494662aa232248d0c9a0b5
Autor:
Yuriy Pomeshchik, Erika Velasquez, Jeovanis Gil, Oxana Klementieva, Ritha Gidlöf, Marie Sydoff, Silvia Bagnoli, Benedetta Nacmias, Sandro Sorbi, Gunilla Westergren-Thorsson, Gunnar K. Gouras, Melinda Rezeli, Laurent Roybon
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-19 (2023)
Abstract The hippocampus is a primary region affected in Alzheimer’s disease (AD). Because AD postmortem brain tissue is not available prior to symptomatic stage, we lack understanding of early cellular pathogenic mechanisms. To address this issue,
Externí odkaz:
https://doaj.org/article/2ae5b16d269b4929b5cc61c410c184d5
Autor:
Claudia Saraceno, Lorenzo Pagano, Valentina Laganà, Andrea Geviti, Silvia Bagnoli, Assunta Ingannato, Salvatore Mazzeo, Antonio Longobardi, Silvia Fostinelli, Sonia Bellini, Alberto Montesanto, Giuliano Binetti, Raffaele Maletta, Benedetta Nacmias, Roberta Ghidoni
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 7035 (2024)
Alzheimer’s Disease (AD) and Frontotemporal Dementia (FTD) are the two major neurodegenerative diseases with distinct clinical and neuropathological profiles. The aim of this report is to conduct a population-based investigation in well-characteriz
Externí odkaz:
https://doaj.org/article/fe286e117a4f49588ebe67f1626aa6b4
Autor:
Salvatore Mazzeo, Michael Lassi, Sonia Padiglioni, Alberto Arturo Vergani, Valentina Moschini, Maenia Scarpino, Giulia Giacomucci, Rachele Burali, Carmen Morinelli, Carlo Fabbiani, Giulia Galdo, Lorenzo Gaetano Amato, Silvia Bagnoli, Filippo Emiliani, Assunta Ingannato, Benedetta Nacmias, Sandro Sorbi, Antonello Grippo, Alberto Mazzoni, Valentina Bessi
Publikováno v:
BMC Neurology, Vol 23, Iss 1, Pp 1-13 (2023)
Abstract Background As disease-modifying therapies (DMTs) for Alzheimer's disease (AD) are becoming a reality, there is an urgent need to select cost-effective tools that can accurately identify patients in the earliest stages of the disease. Subject
Externí odkaz:
https://doaj.org/article/7ef94172f33649e486e42d3ec56c858b
Autor:
Emiliano Giardina, Paola Mandich, Roberta Ghidoni, Nicola Ticozzi, Giacomina Rossi, Chiara Fenoglio, Francesco Danilo Tiziano, Federica Esposito, Sabina Capellari, Benedetta Nacmias, Rossana Mineri, Rosa Campopiano, Luana Di Pilla, Federica Sammarone, Stefania Zampatti, Cristina Peconi, Flavio De Angelis, Ilaria Palmieri, Caterina Galandra, Eleonora Nicodemo, Paola Origone, Fabio Gotta, Clarissa Ponti, Roland Nicsanu, Luisa Benussi, Silvia Peverelli, Antonia Ratti, Martina Ricci, Giuseppe Di Fede, Stefania Magri, Maria Serpente, Serena Lattante, Teuta Domi, Paola Carrera, Elisa Saltimbanco, Silvia Bagnoli, Assunta Ingannato, Alberto Albanese, Fabrizio Tagliavini, Raffaele Lodi, Carlo Caltagirone, Stefano Gambardella, Enza Maria Valente, Vincenzo Silani
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
IntroductionHigh repeat expansion (HRE) alleles in C9orf72 have been linked to both amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD); ranges for intermediate allelic expansions have not been defined yet, and clinical interpretati
Externí odkaz:
https://doaj.org/article/48c2074ccdf6430aa36dbc406509d0c2
Autor:
Michael Lassi, Carlo Fabbiani, Salvatore Mazzeo, Rachele Burali, Alberto Arturo Vergani, Giulia Giacomucci, Valentina Moschini, Carmen Morinelli, Filippo Emiliani, Maenia Scarpino, Silvia Bagnoli, Assunta Ingannato, Benedetta Nacmias, Sonia Padiglioni, Silvestro Micera, Sandro Sorbi, Antonello Grippo, Valentina Bessi, Alberto Mazzoni
Publikováno v:
NeuroImage: Clinical, Vol 38, Iss , Pp 103407- (2023)
Alzheimer’s disease (AD) pathological changes may begin up to decades earlier than the appearance of the first symptoms of cognitive decline. Subjective cognitive decline (SCD) could be the first pre-clinical sign of possible AD, which might be fol
Externí odkaz:
https://doaj.org/article/d00a25eb63e348e1a5f166cca35f2b08
Autor:
Valentina Moschini, Salvatore Mazzeo, Silvia Bagnoli, Sonia Padiglioni, Filippo Emiliani, Giulia Giacomucci, Carmen Morinelli, Assunta Ingannato, Tommaso Freni, Laura Belloni, Camilla Ferrari, Sandro Sorbi, Benedetta Nacmias, Valentina Bessi
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
Objective:HTT is a gene containing a key region of CAG repeats. When expanded beyond 39 repeats, Huntington disease (HD) develops. HTT genes with
Externí odkaz:
https://doaj.org/article/acd892c337f548d2b163c85c1cc2b06d