Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Silvia Armaroli"'
Autor:
Giuseppe Marazzi, Giulio Carzana, Silvia Armaroli, Giuseppe Giacalone, Zappavigna Maria Pia, Patrizia Ferrari, Simona Sputore, Alessandra Benicchio, Alberto Cerri, Banfi Leonardo, Mauro Gobbini, Barbara Moro, R. Micheletti, Marco Torri
Publikováno v:
Bioorganic & Medicinal Chemistry. 18:4275-4299
We report the synthesis and biological properties of novel analogues of Istaroxime acting as positive inotropic compounds through the inhibition of the Na(+),K(+)-ATPase. We explored the chemical space around the position 6 of the steroidal scaffold
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b74eee182ce07b88913258785b0d8658
https://doi.org/10.1016/j.bmc.2010.04.095
https://doi.org/10.1016/j.bmc.2010.04.095
Autor:
Alessandra Benicchio, Banfi Leonardo, Giulio Carzana, Marco Pozzi, Giorgio Fedrizzi, Patrizia Ferrari, Giuseppe Marazzi, Barbara Moro, Mauro Gobbini, Michele Giubileo, R. Micheletti, Silvia Armaroli, Giuseppe Giacalone, Alberto Cerri, Piero Enrico Scotti, Marco Torri
Publikováno v:
Journal of Medicinal Chemistry. 51:4601-4608
We report the synthesis and biological properties of novel inhibitors of the Na(+),K(+)-ATPase as positive inotropic compounds. Following our previously described model from which Istaroxime was generated, the 5alpha,14alpha-androstane skeleton was u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62c6708c430a42be68b2fa9e3d26d19f
https://doi.org/10.1021/jm800257s
https://doi.org/10.1021/jm800257s
Autor:
Daniele Castagnolo, Paula Pera, Maurizio Botta, Gabriele Fontana, Silvia Armaroli, Ezio Bombardelli
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:1579-1583
A small library of 2-deacetoxytaxinine J (DAT-J) 1 derivatives was synthesised and tested in vitro for their reversal activity in human mammary carcinoma MDR cell line MCF7-R. One of the new taxoids showed to be active at 0.1 microM when tested in co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b60dffc1216115075ebf7fed699cca85
https://doi.org/10.1016/j.bmcl.2006.12.101
https://doi.org/10.1016/j.bmcl.2006.12.101
Publikováno v:
Tetrahedron: Asymmetry. 15:941-949
A variety of substituted 1-aryl-2-propenylamines of high enantiomeric purity were prepared via lipase-catalysed resolution of the corresponding racemates. (R)-1-Phenyl-2-propenylamine was further synthesised into (2R,3S)-3-benzoylamino-2-hydroxy-3-ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34b85a23a24888346567ce4e15997c25
https://doi.org/10.1016/j.tetasy.2004.01.035
https://doi.org/10.1016/j.tetasy.2004.01.035
Publikováno v:
ChemInform. 45
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0da2276a10a3a606803c1227406f410b
https://doi.org/10.1002/chin.201429194
https://doi.org/10.1002/chin.201429194
A simple, convenient, and environmentally friendly route to ST1535 employing an iron-catalyzed cross-coupling reaction and butylmagnesium chloride is described.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f8c3c9e0bb4585d5db3ca8f9e886444
http://hdl.handle.net/11585/756802
http://hdl.handle.net/11585/756802
Publikováno v:
ChemInform. 31
trans-Aziridine-2-carboxylic acid derivatives are useful intermediates for the synthesis of threonine or allo-threonine through ring expansion and SN2 displacement, respectively. We describe here the preparation of the Ile-allo-Thr-Gly 11 fragment of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe725508c4e124542dcb6c377fee1925
https://doi.org/10.1002/chin.200031205
https://doi.org/10.1002/chin.200031205
Publikováno v:
Organic Letters. 2:1105-1107
[formula: see text] trans-Aziridine-2-carboxylic acid derivatives are useful intermediates for the synthesis of threonine or allo-threonine through ring expansion and SN2 displacement, respectively. We describe here the preparation of the Ile-allo-Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c55fdd0c92b7417570f68789aad19cb7
https://doi.org/10.1021/ol005659o
https://doi.org/10.1021/ol005659o
Autor:
Paula Pera, Ezio Bombardelli, Silvia Armaroli, Daniele Castagnolo, Maurizio Botta, Gabriele Fontana
Publikováno v:
ChemInform. 38
A small library of 2-deacetoxytaxinine J (DAT-J) 1 derivatives was synthesised and tested in vitro for their reversal activity in human mammary carcinoma MDR cell line MCF7-R. One of the new taxoids showed to be active at 0.1 μM when tested in combi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a591f2859905c7f756618d19ef3d0359
https://doi.org/10.1002/chin.200730165
https://doi.org/10.1002/chin.200730165
Autor:
Mauro Gobbini, Silvia Armaroli, Leonardo Banfi, Alessandra Benicchio, Giulio Carzana, Giorgio Fedrizzi, Patrizia Ferrari, Giuseppe Giacalone, Michele Giubileo, Giuseppe Marazzi, Rosella Micheletti, Barbara Moro, Marco Pozzi, Piero Enrico Scotti, Marco Torri, Alberto Cerri
Publikováno v:
Journal of Medicinal Chemistry; Jul2008, Vol. 51 Issue 15, p4601-4608, 8p