Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Silvia Andreani"'
Autor:
Abdallah Gaballa, Anneli Gebhardt-Wolf, Bastian Krenz, Greta Mattavelli, Mara John, Giacomo Cossa, Silvia Andreani, Christina Schülein-Völk, Francisco Montesinos, Raphael Vidal, Carolin Kastner, Carsten P. Ade, Burkhard Kneitz, Georg Gasteiger, Peter Gallant, Mathias Rosenfeldt, Angela Riedel, Martin Eilers
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract In pancreatic ductal adenocarcinoma (PDAC), endogenous MYC is required for S-phase progression and escape from immune surveillance. Here we show that MYC in PDAC cells is needed for the recruitment of the PAF1c transcription elongation compl
Externí odkaz:
https://doaj.org/article/8a9d10af203b42eb8a6cbb3a3a12d74d
Autor:
Sabrina D’Agosto, Elena Fiorini, Francesco Pezzini, Pietro Delfino, Michele Simbolo, Caterina Vicentini, Silvia Andreani, Paola Capelli, Borislav Rusev, Rita T. Lawlor, Claudio Bassi, Luca Landoni, Antonio Pea, Claudio Luchini, Aldo Scarpa, Vincenzo Corbo
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are rare and highly heterogeneous neoplasms whose incidence has markedly increased over the last decades. A grading system based on the tumor cells’ proliferation index predicts high-risk for
Externí odkaz:
https://doaj.org/article/824aa1c5f3f44c85ac69f1bead467746
Autor:
Luca Nicosia, Filippo Alongi, Silvia Andreani, Ruggero Ruggieri, Borislav Rusev, Beatrice Mantoan, Rita Teresa Lawlor, Antonio Pea, Aldo Scarpa, Linda Agolli, Vincenzo Corbo, Sabrina D’Agosto
Publikováno v:
Biomedicines, Vol 8, Iss 12, p 609 (2020)
Pancreatic ductal adenocarcinoma (PDAC) is highly refractory to systemic treatment, including radiotherapy (RT) either as alone or in combination with chemotherapy. Magnetic resonance (MR)-guided RT is a novel treatment technique which conjugates the
Externí odkaz:
https://doaj.org/article/e87510d738eb4c9986b946bd20bd8e7d
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 11, p 2766 (2019)
Pancreatic ductal adenocarcinoma (PDA) is a malignancy of the exocrine pancreas with the worst prognosis among all solid tumours, and soon to become the second leading cause of cancer-related deaths. A more comprehensive understanding of the molecula
Externí odkaz:
https://doaj.org/article/be629dbd0d794421a4d505416af24dc3
Autor:
Sabrina D’Agosto, Francesco Pezzini, Lisa Veghini, Pietro Delfino, Claudia Fiorini, Gael D. Temgue Tane, Anais Del Curatolo, Caterina Vicentini, Giorgia Ferrari, Davide Pasini, Silvia Andreani, Francesca Lupo, Elena Fiorini, Giulia Lorenzon, Rita T. Lawlor, Borislav Rusev, Antonia Malinova, Claudio Luchini, Michele Milella, Elisabetta Sereni, Antonio Pea, Claudio Bassi, Peter Bailey, Aldo Scarpa, Emilio Bria, Vincenzo Corbo
Publikováno v:
Oncogene. 41:4371-4384
Transcriptomic analyses of pancreatic ductal adenocarcinoma (PDAC) have identified two major epithelial subtypes with distinct biology and clinical behaviours. Here, we aimed to clarify the role of FGFR1 and FGFR4 in the definition of aggressive PDAC
Autor:
Francesca Lupo, Francesco Pezzini, Elena Fiorini, Annalisa Adamo, Lisa Veghini, Michele Bevere, Cristina Frusteri, Pietro Delfino, Sabrina D’Agosto, Silvia Andreani, Geny Piro, Antonia Malinova, Francesco De Sanctis, Davide Pasini, Rita T. Lawlor, Chang-il Hwang, Carmine Carbone, Ivano Amelio, Peter Bailey, Vincenzo Bronte, David Tuveson, Aldo Scarpa, Stefano Ugel, Vincenzo Corbo
Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease with few available therapeutic options. Two transcriptional cancer cell states have been consistently reported in PDAC, with the basal-like/squamous phenotype displaying a more aggressive bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6039dd8c6af07f1f4302630d17bce71b
https://doi.org/10.1101/2023.02.25.529923
https://doi.org/10.1101/2023.02.25.529923
Autor:
Maria Chiara De Santis, Luca Gozzelino, Jean Piero Margaria, Andrea Costamagna, Edoardo Ratto, Federico Gulluni, Enza Di Gregorio, Erica Mina, Nicla Lorito, Marina Bacci, Rossano Lattanzio, Gianluca Sala, Paola Cappello, Francesco Novelli, Elisa Giovannetti, Caterina Vicentini, Silvia Andreani, Pietro Delfino, Vincenzo Corbo, Aldo Scarpa, Paolo Ettore Porporato, Andrea Morandi, Emilio Hirsch, Miriam Martini
Publikováno v:
Gut, 72(2), 360-371. BMJ Publishing Group
de Santis, M C, Gozzelino, L, Margaria, J P, Costamagna, A, Ratto, E, Gulluni, F, di Gregorio, E, Mina, E, Lorito, N, Bacci, M, Lattanzio, R, Sala, G, Cappello, P, Novelli, F, Giovannetti, E, Vicentini, C, Andreani, S, Delfino, P, Corbo, V, Scarpa, A, Porporato, P E, Morandi, A, Hirsch, E & Martini, M 2022, ' Lysosomal lipid switch sensitises to nutrient deprivation and mTOR targeting in pancreatic cancer ', Gut, vol. 72, no. 2, pp. 360-371 . https://doi.org/10.1136/gutjnl-2021-325117
de Santis, M C, Gozzelino, L, Margaria, J P, Costamagna, A, Ratto, E, Gulluni, F, di Gregorio, E, Mina, E, Lorito, N, Bacci, M, Lattanzio, R, Sala, G, Cappello, P, Novelli, F, Giovannetti, E, Vicentini, C, Andreani, S, Delfino, P, Corbo, V, Scarpa, A, Porporato, P E, Morandi, A, Hirsch, E & Martini, M 2022, ' Lysosomal lipid switch sensitises to nutrient deprivation and mTOR targeting in pancreatic cancer ', Gut, vol. 72, no. 2, pp. 360-371 . https://doi.org/10.1136/gutjnl-2021-325117
ObjectivePancreatic ductal adenocarcinoma (PDAC) is an aggressive disease with limited therapeutic options. However, metabolic adaptation to the harsh PDAC environment can expose liabilities useful for therapy. Targeting the key metabolic regulator m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a773704449eb1efc62289fcb4007343a
http://hdl.handle.net/2318/1861832
http://hdl.handle.net/2318/1861832
Autor:
Dante Romagnoli, Elena Turola, Mariagrazia Del Buono, Pamela Sighinolfi, Maria Marsico, Nicola De Maria, Gloria Taliani, Antonino Maiorana, Laura Bristot, Francesca Faillaci, Luca Di Lena, Laura Turco, Liliana Chemello, M.L. Martínez-Chantar, Paolo Magistri, Savino Bruno, Silvia Andreani, Erica Villa, Barbara Lei, Paola Manni, Rosina Maria Critelli, Luisa Cavalletto, L. Marzi, Filippo Schepis, Cristian Caporali, Veronica Bernabucci, Federica D'Ambrosio, Marcello Bianchini, Gianluigi Giannelli, Fabiola Milosa, Paola Todesca, Gabriele Vandelli, Fabrizio Di Benedetto
Publikováno v:
Hepatology (Baltimore, Md.)
Recent reports suggested that direct acting antivirals (DAAs) might favor hepatocellular carcinoma (HCC). In study 1, we studied the proangiogenic liver microenvironment in 242 DAA‐treated chronic hepatitis C patients with advanced fibrosis. Angiop
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 11, p 2766 (2019)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Pancreatic ductal adenocarcinoma (PDA) is a malignancy of the exocrine pancreas with the worst prognosis among all solid tumours, and soon to become the second leading cause of cancer-related deaths. A more comprehensive understanding of the molecula
Autor:
Cristian Caporali, Filippo Schepis, Francesca Faillaci, Rosario Condello, Mariagrazia Del Buono, Gianluigi Giannelli, Fabiola Milosa, M.L. Martínez-Chantar, Antonino Maiorana, Silvia Andreani, L. Marzi, Nicola De Maria, Francesco Dituri, Rosina Maria Critelli, Fabrizio Di Benedetto, Erica Villa, Paola Manni, Barbara Lei, Elena Turola, Pamela Sighinolfi
Publikováno v:
Cell Death & Disease
In HCC, tumor microenvironment, heavily influenced by the underlying chronic liver disease, etiology and stage of the tissue damage, affects tumor progression and determines the high heterogeneity of the tumor. Aim of this study was to identify the c