Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Silvia Aldi"'
Autor:
Silvia Aldi, Ljubica Perisic Matic, Gregory Hamm, Daniëlle van Keulen, Dennie Tempel, Kim Holmstrøm, Agnieszka Szwajda, Boye Schnack Nielsen, Valur Emilsson, Rima Ait-Belkacem, Mariette Lengquist, Gabrielle Paulsson-Berne, Per Eriksson, Jan H.N. Lindeman, Alain J. Gool, Jonathan Stauber, Ulf Hedin, Eva Hurt-Camejo
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 10, Iss , Pp 17-28 (2018)
Variants in the PLPP3 gene encoding for lipid phosphate phosphohydrolase 3 have been associated with susceptibility to atherosclerosis independently of classical risk factors. PLPP3 inactivates lysophosphatidic acid (LPA), a pro-inflammatory, pro-thr
Externí odkaz:
https://doaj.org/article/7bfc8ac6211a4952996ab2d554be695f
Autor:
Sylvia T Nurnberg, Karen Cheng, Azad Raiesdana, Ramendra Kundu, Clint L Miller, Juyong B Kim, Komal Arora, Ivan Carcamo-Oribe, Yiqin Xiong, Nikhil Tellakula, Vivek Nanda, Nikitha Murthy, William A Boisvert, Ulf Hedin, Ljubica Perisic, Silvia Aldi, Lars Maegdefessel, Milos Pjanic, Gary K Owens, Michelle D Tallquist, Thomas Quertermous
Publikováno v:
PLoS Genetics, Vol 11, Iss 5, p e1005155 (2015)
Recent genome wide association studies have identified a number of genes that contribute to the risk for coronary heart disease. One such gene, TCF21, encodes a basic-helix-loop-helix transcription factor believed to serve a critical role in the deve
Externí odkaz:
https://doaj.org/article/634f0f095de147ef80655c3a26fbf021
Autor:
Rikard Holmdahl, Silvia Aldi, Alf Kastbom, Jie Yang, Christopher Sjöwall, Erik Lönnblom, Johan Viljanen, Inger Gjertsson, Jan Kihlberg, Changrong Ge, Weiwei Cai, Lei Cheng
Publikováno v:
ACS Chemical Biology. 15:2605-2615
Type II collagen (CII) is the most abundant protein in joint cartilage. Antibodies to CII appear around the clinical onset of the autoimmune disease rheumatoid arthritis (RA) in a subset of patients. They target specific epitopes on CII and can be pa
Autor:
Roland Baumgartner, Philip Dusart, Björn Gustafsson, Mona Ahmed, Kenneth Caidahl, Silvia Aldi, Ulf Hedin
Publikováno v:
International Journal of Nanomedicine. 14:3723-3741
Background: Inflammation and accumulation of macrophages are key features of unstable atherosclerotic plaques. The ability of macrophages to take up molecular probes can be exploited in new clinical imaging methods for the detection of unstable ather
Autor:
Karl-Henrik Grinnemo, Mariette Lengquist, Cecilia Österholm, Ljubica Perisic Matic, Marie Löfling, Linnéa Eriksson, Malin Kronqvist, Lasse Folkersen, Lars Maegdefessel, Silvia Aldi, Ulf Hedin, Jin-Ping Li
Publikováno v:
Atherosclerosis. 283:127-136
Background and aims Calcification is a hallmark of advanced atherosclerosis and an active process akin to bone remodeling. Heparanase (HPSE) is an endo-β-glucuronidase, which cleaves glycosaminoglycan chains of heparan sulfate proteoglycans. The rol
Autor:
Johan Viljanen, Erik Lönnblom, Changrong Ge, Jie Yang, Lei Cheng, Silvia Aldi, Weiwei Cai, Alf Kastbom, Christopher Sjöwall, Gregg B. Fields, Inger Gjertsson, Rikard Holmdahl, Jan Kihlberg
Publikováno v:
ACS Chemical Biology. 15:3072-3072
Autor:
Jan H.N. Lindeman, Ulf de Faire, Anders Hamsten, Ida Ericsson, Ewa Ehrenborg, Maria Gonzalez Diez, Silvia Aldi, Joëlle Magné, Thomas Quertermous, Valentina Paloschi, Per Eriksson, Clint L. Miller, Elena Tremoli, Maria Sabater-Lleal, Mariette Lengquist, Ljubica Perisic Matic, Ulf Hedin, Damiano Baldassarre, Hong Jin, Mattias Vesterlund, Yuhuang Li, Anton Razuvaev, Fabrizio Veglia, Urszula Rykaczewska, Janne Lehtiö, Gabrielle Paulsson-Berne, Vladana Vukojević, Göran K. Hansson, Jacob Odeberg, Steve E. Humphries, Joy Roy, Lars Maegdefessel, Malin Kronqvist, Samuel Röhl
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology, 36(9), 1947-1961
Arterioscler Thromb Vasc Biol
Arterioscler Thromb Vasc Biol
Objective— Key augmented processes in atherosclerosis have been identified, whereas less is known about downregulated pathways. Here, we applied a systems biology approach to examine suppressed molecular signatures, with the hypothesis that they ma
Autor:
Lasse Folkersen, Joy Roy, Göran K. Hansson, Lars Maegdefessel, Anders Gabrielsen, S. Akesson, Gabrielle Paulsson-Berne, Mariette Lengquist, Jacob Odeberg, Silvia Aldi, Anton Razuvaev, Craig E. Wheelock, Ulf Hedin, Ljubica Perisic, Y. Sun
Publikováno v:
Journal of Internal Medicine. 279:293-308
Background Embolism from unstable atheromas in the carotid bifurcation is a major cause of stroke. Here, we analysed gene expression in endarterectomies from patients with symptomatic (S) and asymptomatic (AS) carotid stenosis to identify pathways li
Autor:
Mariette Lengquist, Ljubica Perisic Matic, Gabrielle Paulsson-Berne, Dennie Tempel, Gregory Hamm, Jan H.N. Lindeman, Jonathan Stauber, Rima Ait-Belkacem, Danielle van Keulen, Alain J. Gool, Per Eriksson, Kim Holmstrøm, Agnieszka Szwajda, Silvia Aldi, Ulf Hedin, Boye Schnack Nielsen, Valur Emilsson, Eva Hurt-Camejo
Publikováno v:
Molecular therapy Methods & clinical development, 10, 17-28
Molecular Therapy. Methods & Clinical Development
Molecular Therapy-Methods and Clinical Development, 10, 17-28
Molecular Therapy: Methods & Clinical Development, Vol 10, Iss, Pp 17-28 (2018)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy-Methods and Clinical Development, 10, 17-28
Molecular Therapy: Methods & Clinical Development, Vol 10, Iss, Pp 17-28 (2018)
Publisher's version (útgefin grein).
Variants in thePLPP3gene encoding for lipid phosphatephosphohydrolase 3 have been associated with susceptibilityto atherosclerosis independently of classical risk factors.PLPP3 inactivates lysophosphatidic a
Variants in thePLPP3gene encoding for lipid phosphatephosphohydrolase 3 have been associated with susceptibilityto atherosclerosis independently of classical risk factors.PLPP3 inactivates lysophosphatidic a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dadf9e53f321f0dac657f2bcacab80bf
https://hdl.handle.net/1887/86841
https://hdl.handle.net/1887/86841
Autor:
Silvia Aldi, Domenico Palumberi, Leonardo Ermini, Sandra Donnini, Floriana Rosati, Marina Ziche, Federica Finetti
Publikováno v:
Journal of Cellular Biochemistry. 111:229-238
In a previous article, we demonstrated the existence of fucosyl-containing O-glycans forms of nucleolin in bovine post-capillary venular endothelial cells (CVEC) and malignant cultured human A431 cells. The tool for this discovery was an antibody fou