Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Silvia, Peppicelli"'
A potentiated cooperation of carbonic anhydrase IX and histone deacetylase inhibitors against cancer
Autor:
Jessica Ruzzolini, Anna Laurenzana, Elena Andreucci, Silvia Peppicelli, Francesca Bianchini, Fabrizio Carta, Claudiu T. Supuran, Maria Novella Romanelli, Chiara Nediani, Lido Calorini
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 391-397 (2020)
The emergence of tumour recurrence and resistance limits the survival rate for most tumour-bearing patients. Only, combination therapies targeting pathways involved in the induction and in the maintenance of cancer growth and progression might potent
Externí odkaz:
https://doaj.org/article/30e6a7e168db4526811b3fdafb8e7156
Autor:
Silvia Peppicelli, Elena Andreucci, Jessica Ruzzolini, Francesca Bianchini, Chiara Nediani, Claudiu T. Supuran, Lido Calorini
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 1185-1193 (2020)
Mesenchymal stem cells (MSC) take part to solid tumour-associated stroma and critically influence progression of malignancy. Our study represents a striking example of melanoma progression to a more malignant and resistant phenotype promoted by MSC a
Externí odkaz:
https://doaj.org/article/4f2e70c3491c498b967bab91ab55aa4d
Autor:
Anna Laurenzana, Francesca Margheri, Alessio Biagioni, Anastasia Chillà, Nicola Pimpinelli, Jessica Ruzzolini, Silvia Peppicelli, Elena Andreucci, Lido Calorini, Simona Serratì, Mario Del Rosso, Gabriella Fibbi
Publikováno v:
EBioMedicine, Vol 39, Iss , Pp 194-206 (2019)
Background: BRAF inhibitor (BRAF-I) therapy for melanoma patients harboring the V600E mutation is initially highly effective, but almost all patients relapse within a few months. Understanding the molecular mechanisms behind BRAF-I responsiveness and
Externí odkaz:
https://doaj.org/article/3b168ed4a9a24810bf9eaacbdb6b0472
Autor:
Elena Andreucci, Jessica Ruzzolini, Silvia Peppicelli, Francesca Bianchini, Anna Laurenzana, Fabrizio Carta, Claudiu T. Supuran, Lido Calorini
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 117-123 (2019)
Drug combination represents one of the most accredited strategies of cancer therapy able to improve drug efficacy and possibly overcome drug resistance. Among the agents used to complement conventional chemotherapy, carbonic anhydrase IX (CAIX) inhib
Externí odkaz:
https://doaj.org/article/ee8ce283a7784533aed00eb6f59d9861
Autor:
Sara Peri, Jessica Ruzzolini, Silvia Urciuoli, Giampaolo Versienti, Alessio Biagioni, Elena Andreucci, Silvia Peppicelli, Francesca Bianchini, Andrea Bottari, Lido Calorini, Chiara Nediani, Lucia Magnelli, Laura Papucci
Publikováno v:
Antioxidants, Vol 11, Iss 9, p 1762 (2022)
Oleocanthal, a minor polar compound in extra-virgin olive (EVO) oil, contains anticancer properties, which should be encouraged in its use in oncology. Gastric Cancer (GC), a very aggressive human cancer, is often diagnosed at advanced stages, when s
Externí odkaz:
https://doaj.org/article/b72a73ae746f4744b5036d41bece2efa
Autor:
Alessio Biagioni, Anastasia Chillà, Mario Del Rosso, Gabriella Fibbi, Francesca Scavone, Elena Andreucci, Silvia Peppicelli, Francesca Bianchini, Lido Calorini, Anna Li Santi, Pia Ragno, Francesca Margheri, Anna Laurenzana
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
uPAR is a globular protein, tethered to the cell membrane by a GPI-anchor involved in several cancer-related properties and its overexpression commonly correlates with poor prognosis and metastasis. We investigated the consequences of uPAR irreversib
Externí odkaz:
https://doaj.org/article/20a77ee24da847da832d2ea4fc6f241a
Autor:
Elena Andreucci, Silvia Pietrobono, Silvia Peppicelli, Jessica Ruzzolini, Francesca Bianchini, Alessio Biagioni, Barbara Stecca, Lido Calorini
Publikováno v:
Cell Communication and Signaling, Vol 16, Iss 1, Pp 1-13 (2018)
Abstract Background Deregulated metabolism is a hallmark of cancer and recent evidence underlines that targeting tumor energetics may improve therapy response and patient outcome. Despite the general attitude of cancer cells to exploit the glycolytic
Externí odkaz:
https://doaj.org/article/4a51086552cd4cd5acc24c0ee2ace7c6
Publikováno v:
Cancer and Metastasis Reviews. 41:935-951
Tumour vascularisation is vital for cancer sustainment representing not only the main source of nutrients and oxygen supply but also an escape route for single or clustered cancer cells that, once detached from the primary mass, enter the blood circu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddd50f8ac67cd23e37f0329f83dcb98d
https://doi.org/10.1007/s10555-022-10067-x
https://doi.org/10.1007/s10555-022-10067-x
Autor:
Jessica Ruzzolini, Sofia Chioccioli, Noemi Monaco, Silvia Peppicelli, Elena Andreucci, Silvia Urciuoli, Annalisa Romani, Cristina Luceri, Katia Tortora, Lido Calorini, Giovanna Caderni, Chiara Nediani, Francesca Bianchini
Publikováno v:
Antioxidants, Vol 10, Iss 10, p 1577 (2021)
Oleuropein, the major compound found in olive leaves, has been reported to exert numerous pharmacological properties, including anti-inflammatory, anti-diabetic and anti-cancer effects. The purpose of this study was to evaluate, for the first time, t
Externí odkaz:
https://doaj.org/article/5d249e1ad8d64ec487798fd729c633a8
Autor:
Angela Silvano, Giulio Menegazzi, Silvia Peppicelli, Caterina Mancini, Alessio Biagioni, Alessandro Tubita, Ignazia Tusa, Jessica Ruzzolini, Matteo Lulli, Elisabetta Rovida, Persio Dello Sbarba
Publikováno v:
Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics. 29:33-46
This study was directed to deepen the effects of nutrient shortage on BCR/Ablprotein expression and signaling in chronic myeloid leukemia (CML) cells. The backbone of the study was cell culture in medium lacking glucose, the consumption of which we h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8cafd450c597f2e7d3e5361aaa5a92e
https://doi.org/10.3727/096504022x16442289212164
https://doi.org/10.3727/096504022x16442289212164