Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Silvia, Pelucchi"'
Publikováno v:
Chemical Engineering Transactions, Vol 105 (2023)
Total indirect greenhouse gas (GHG) emissions from oil and gas operations today are around 5,200 Mt of carbon dioxide equivalent (CO2-eq) yearly, 15% of total energy sector GHG emissions. Most of these emissions occur due to natural gas leaks. Methan
Externí odkaz:
https://doaj.org/article/1d372aa5c0d743f4b596a18c99d1d0cc
Autor:
Elisa Focchi, Clara Cambria, Lara Pizzamiglio, Luca Murru, Silvia Pelucchi, Laura D’Andrea, Silvano Piazza, Lorenzo Mattioni, Maria Passafaro, Elena Marcello, Giovanni Provenzano, Flavia Antonucci
Publikováno v:
Cell Death and Disease, Vol 13, Iss 7, Pp 1-13 (2022)
Abstract Interest in the function of ataxia-telangiectasia-mutated protein (ATM) is extensively growing as evidenced by preclinical studies that continuously link ATM with new intracellular pathways. Here, we exploited Atm +/− and Atm −/− mice
Externí odkaz:
https://doaj.org/article/034bec23720144fca3240bc13c6dcaa0
Autor:
Cristina Marisol Castillo Bautista, Kristin Eismann, Marc Gentzel, Silvia Pelucchi, Jerome Mertens, Hannah E. Walters, Maximina H. Yun, Jared Sterneckert
Publikováno v:
Cells, Vol 12, Iss 18, p 2247 (2023)
Aging is associated with the disruption of protein homeostasis and causally contributes to multiple diseases, including amyotrophic lateral sclerosis (ALS). One strategy for restoring protein homeostasis and protecting neurons against age-dependent d
Externí odkaz:
https://doaj.org/article/fa8aa0500c5d451eb80a3e477c6cd4bd
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Cyclase-associated protein (CAP) has been discovered three decades ago in budding yeast as a protein that associates with the cyclic adenosine monophosphate (cAMP)-producing adenylyl cyclase and that suppresses a hyperactive RAS2 variant. Since that
Externí odkaz:
https://doaj.org/article/a07679672ea94f9ab6bc76dbdc7e9777
Autor:
Anna Di Maio, Arianna De Rosa, Silvia Pelucchi, Martina Garofalo, Benedetta Marciano, Tommaso Nuzzo, Fabrizio Gardoni, Andrea M. Isidori, Monica Di Luca, Francesco Errico, Andrea De Bartolomeis, Elena Marcello, Alessandro Usiello
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 3, p 1539 (2022)
Schizophrenia (SCZ) is a mental illness characterized by aberrant synaptic plasticity and connectivity. A large bulk of evidence suggests genetic and functional links between postsynaptic abnormalities and SCZ. Here, we performed quantitative PCR and
Externí odkaz:
https://doaj.org/article/2640aa76a5e64ad9a81ee90ee9d99e7d
Autor:
Alerie G. de la Fuente, Silvia Pelucchi, Jerome Mertens, Monica Di Luca, Daniela Mauceri, Elena Marcello
Publikováno v:
British Journal of Pharmacology.
Ageing is the main risk factor common to most primary neurodegenerative disorders. Indeed, age-related brain alterations have been long considered to predispose to neurodegeneration. Although protein misfolding and the accumulation of toxic protein a
Autor:
Patricia Regina Manzine, Miren Ettcheto, Amanda Cano, Oriol Busquets, Elena Marcello, Silvia Pelucchi, Monica Di Luca, Kristina Endres, Jordi Olloquequi, Antoni Camins, Márcia Regina Cominetti
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 113, Iss , Pp - (2019)
Alzheimer’s disease (AD) represents a global burden in the economics of healthcare systems. Amyloid-β (Aβ) peptides are formed by amyloid-β precursor protein (AβPP) cleavage, which can be processed by two pathways. The cleavage by the α-secret
Externí odkaz:
https://doaj.org/article/49280d61f9224dd297d985fc0c9b160b
Autor:
Raffaella Morini, Silvia Ferrara, Fabio Perrucci, Stefania Zambetti, Silvia Pelucchi, Elena Marcello, Fabrizio Gardoni, Flavia Antonucci, Michela Matteoli, Elisabetta Menna
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Actin-based remodeling underlines spine morphogenesis and plasticity and is crucially involved in the processes that constantly reshape the circuitry of the adult brain in response to external stimuli, leading to learning and memory formation and sup
Externí odkaz:
https://doaj.org/article/188e19dd1fb34680aa501242b9ea2141
Autor:
Izabela Pereira Vatanabe, Rafaela Peron, Marina Mantellatto Grigoli, Silvia Pelucchi, Giulia De Cesare, Thamires Magalhães, Patricia Regina Manzine, Marcio Luiz Figueredo Balthazar, Monica Di Luca, Elena Marcello, Marcia Regina Cominetti
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 5, p 2416 (2021)
ADAM10 is the main α-secretase that participates in the non-amyloidogenic cleavage of amyloid precursor protein (APP) in neurons, inhibiting the production of β-amyloid peptide (Aβ) in Alzheimer’s disease (AD). Strong recent evidence indicates t
Externí odkaz:
https://doaj.org/article/8552cce2af4a4f63a1061442f2c0422f
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 3, p 908 (2020)
Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by Aβ-driven synaptic dysfunction in the early phases of pathogenesis. In the synaptic context, the actin cytoskeleton is a crucial element to maintain the dendritic spine arch
Externí odkaz:
https://doaj.org/article/40ac0c877c2a449aac46cb3b3a10c2b9