Zobrazeno 1 - 10
of 697
pro vyhledávání: '"Silvia, Novello"'
Autor:
Muhlis Akman, Ciro Monteleone, Gabriella Doronzo, Martina Godel, Francesca Napoli, Alessandra Merlini, Virginia Campani, Valeria Nele, Elisa Balmas, Tatiana Chontorotzea, Simona Fontana, Sabrina Digiovanni, Francesca Alice Barbu, Elena Astanina, Niloufar Jafari, Iris Chiara Salaroglio, Joanna Kopecka, Giuseppe De Rosa, Thomas Mohr, Alessandro Bertero, Luisella Righi, Silvia Novello, Giorgio Vittorio Scagliotti, Federico Bussolino, Chiara Riganti
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-23 (2024)
Abstract Background In non-small cell lung cancer (NSCLC) the efficacy of chemo-immunotherapy is affected by the high expression of drug efflux transporters as ABCC1 and by the low expression of ABCA1, mediating the isopentenyl pyrophosphate (IPP)-de
Externí odkaz:
https://doaj.org/article/4a6851a8a8824044acb7cc89ddb408bf
Autor:
Rossella Scardaci, Ewa Berlinska, Pietro Scaparone, Sandra Vietti Michelina, Edoardo Garbo, Silvia Novello, David Santamaria, Chiara Ambrogio
Publikováno v:
Molecular Oncology, Vol 18, Iss 6, Pp 1355-1377 (2024)
Mutations in the RAS–RAF–MEK–ERK pathway are frequent alterations in cancer and RASopathies, and while RAS oncogene activation alone affects 19% of all patients and accounts for approximately 3.4 million new cases every year, less frequent alte
Externí odkaz:
https://doaj.org/article/040c4eda48b14ae499f075c7421fd897
Autor:
Marco Sposito, Lorenzo Belluomini, Riccardo Nocini, Jessica Insolda, Ilaria Mariangela Scaglione, Jessica Menis, Michele Simbolo, Antonio Lugini, Federica Buzzacchino, Francesco Verderame, Francesca Spinnato, Giuseppe Aprile, Lorenzo Calvetti, Mario Occhipinti, Daniele Marinelli, Antonello Veccia, Fiorella Lombardo, Hector José Soto Parra, Francesco Ferraù, Clementina Savastano, Camilla Porta, Lorenzo Pradelli, Emilia Sicari, Silvia Castellani, Umberto Malapelle, Silvia Novello, Emilio Bria, Sara Pilotto, Michele Milella
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionTo date, for all non-small cell lung cancer (NSCLC) cases, it is recommended to test for driver alterations to identify actionable therapeutic targets. In this light, comprehensive genomic profiling (CGP) with next generation sequencing (
Externí odkaz:
https://doaj.org/article/621ce51d458b4fc3977c14fc53ea9212
Autor:
Davide Seminati, Vincenzo L'Imperio, Gabriele Casati, Joranda Ceku, Daniela Pilla, Carla Rossana Scalia, Gianluca Gragnano, Francesco Pepe, Pasquale Pisapia, Luca Sala, Diego Luigi Cortinovis, Francesca Bono, Umberto Malapelle, Giancarlo Troncone, Silvia Novello, Fabio Pagni
Publikováno v:
Heliyon, Vol 10, Iss 7, Pp e29272- (2024)
Background: The molecular diagnostic and therapeutic pathway of Non-Small Cell Lung Cancer (NSCLC) stands as a successful example of precision medicine. The scarcity of material and the increasing number of biomarkers to be tested have prompted the r
Externí odkaz:
https://doaj.org/article/8f0aa46a90554e4cba024ba4d722c325
Autor:
Alessio Rizzo, Ornella Cantale, Andrea Mogavero, Lucia Garetto, Manuela Racca, Tiziana Venesio, Shobana Anpalakhan, Silvia Novello, Vanesa Gregorc, Giuseppe Luigi Banna
Publikováno v:
Thoracic Cancer, Vol 14, Iss 24, Pp 2473-2483 (2023)
Abstract Background Inflammation in non‐small cell lung cancer (NSCLC) may impair the response to immune checkpoint inhibitors (ICIs) and can be indicated by peripheral blood inflammatory indexes. 2‐deoxy‐2‐[18F]fluoro‐D‐glucose positron
Externí odkaz:
https://doaj.org/article/6ea1188252e842478259d526a9596ccf
Autor:
Marco Donatello Delcuratolo, Andrea Modrego-Sánchez, Maristella Bungaro, Beatriz Antón-Pascual, Santiago Teran, Valentina Dipace, Silvia Novello, Rocio Garcia-Carbonero, Francesco Passiglia, Cristina Graválos-Castro
Publikováno v:
Journal of Molecular Pathology, Vol 4, Iss 3, Pp 128-155 (2023)
Colorectal cancer is one of the most prevalent cancers nowadays. In the metastatic setting, diagnosis and treatment have relied on tumor tissue analysis. However, the different limitations of this approach have recently opened the door to the introdu
Externí odkaz:
https://doaj.org/article/ef5052c039fe40a7b4f817d3098b8874
Publikováno v:
Cancers, Vol 16, Iss 11, p 2018 (2024)
For patients diagnosed with advanced HER2-altered non-small cell lung cancer (NSCLC), the current standard of care is represented by a platinum-pemetrexed-based chemotherapy, eventually in combination with immunotherapy. Different pan-HER tyrosine ki
Externí odkaz:
https://doaj.org/article/77bae110b6284a29bc57ca18971dc896
Autor:
Giulio Rossi, Luisella Righi, Francesca Barbisan, Marcello Tiseo, Paolo Spagnolo, Federica Grosso, Pasquale Pisapia, Umberto Malapelle, Marika Sculco, Irma Dianzani, Laura Abate-Daga, Maria Cristina Davolio, Giovanni Luca Ceresoli, Domenico Galetta, Giulia Pasello, Silvia Novello, Paolo Bironzo
Publikováno v:
Journal of Personalized Medicine, Vol 14, Iss 4, p 394 (2024)
The pathologic diagnosis of pleural mesothelioma is generally based on international guidelines, but no compulsory points based on different drugs approvals in different European countries are required to be reported. According to the last (2021) edi
Externí odkaz:
https://doaj.org/article/cc7d3f236f6742d4b756b908f9d42440
Autor:
Francesca Bersani, Francesca Picca, Deborah Morena, Luisella Righi, Francesca Napoli, Mariangela Russo, Daniele Oddo, Giuseppe Rospo, Carola Negrino, Barbara Castella, Marco Volante, Angela Listì, Vanessa Zambelli, Federica Benso, Fabrizio Tabbò, Paolo Bironzo, Emanuele Monteleone, Valeria Poli, Filippo Pietrantonio, Federica Di Nicolantonio, Alberto Bardelli, Carola Ponzetto, Silvia Novello, Giorgio V. Scagliotti, Riccardo Taulli
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-19 (2023)
Abstract Background MET-driven acquired resistance is emerging with unanticipated frequency in patients relapsing upon molecular therapy treatments. However, the determination of MET amplification remains challenging using both standard and next-gene
Externí odkaz:
https://doaj.org/article/b85e50ab7db14533b177127c3b4c0360
Autor:
Silvia Novello, Chiara Riganti, Luisella Righi, Fabrizio Tabbò, Lars van der Veen, Michael Lahn, Giusy Di Conza, Giorgio Scagliotti, Laurence Neff
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/bda83d6324b24941ba90ba45ab95c59d