Zobrazeno 1 - 10
of 348
pro vyhledávání: '"Silvia, Deaglio"'
Autor:
Adele Tanzi, Lola Buono, Cristina Grange, Corinne Iampietro, Alessia Brossa, Fanny Oliveira Arcolino, Maddalena Arigoni, Raffaele Calogero, Laura Perin, Silvia Deaglio, Elena Levtchenko, Licia Peruzzi, Benedetta Bussolati
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Background Personalized disease models are crucial for evaluating how diseased cells respond to treatments, especially in case of innovative biological therapeutics. Extracellular vesicles (EVs), nanosized vesicles released by cells for inte
Externí odkaz:
https://doaj.org/article/1d0980a33a23454f942994924d92a61f
Autor:
Matteo Bianco, Noemi Giordano, Valentina Gazzola, Carloalberto Biolè, Giulia Nangeroni, Maurizio Lazzero, Giulia Margherita Brach del Prever, Fiorenza Mioli, Giulia Gobello, Amir Hassan Mousavi, Monica Guidante, Silvia Deaglio, Daniela Francesca Giachino, Alessandra Chinaglia
Publikováno v:
Cardiogenetics, Vol 14, Iss 3, Pp 122-131 (2024)
Cardiomyopathies have evolved from being considered rare and idiopathic to being increasingly linked to genetic factors. This shift was enabled by advancements in understanding genetic variants and the widespread use of next generation sequencing (NG
Externí odkaz:
https://doaj.org/article/312ae3aa402e4e2ca8aa6ae436e2d5f3
Autor:
Monica Sorbini, MS, Enrico Aidala, MD, Tullia Carradori, MS, Francesco Edoardo Vallone, MS, Gabriele Maria Togliatto, PhD, Cristiana Caorsi, PhD, Morteza Mansouri, MD, Paola Burlo, MD, Tiziana Vaisitti, PhD, Antonio Amoroso, MD, Silvia Deaglio, MD, PhD, Carlo Pace Napoleone, MD
Publikováno v:
Transplantation Direct, Vol 10, Iss 10, p e1689 (2024)
Background. Endomyocardial biopsy (EMB) is considered the gold-standard method to diagnose rejection after heart transplantation. However, the many disadvantages and potential complications of this test restrict its routine application, particularly
Externí odkaz:
https://doaj.org/article/e3d88ecd8ea1455bb951eae3ba278b07
Autor:
Luca Ponzone, Valentina Audrito, Claudia Landi, Enrico Moiso, Chiara Levra Levron, Sara Ferrua, Aurora Savino, Nicoletta Vitale, Massimiliano Gasparrini, Lidia Avalle, Lorenza Vantaggiato, Enxhi Shaba, Beatrice Tassone, Stefania Saoncella, Francesca Orso, Daniele Viavattene, Eleonora Marina, Irene Fiorilla, Giulia Burrone, Youssef Abili, Fiorella Altruda, Luca Bini, Silvia Deaglio, Paola Defilippi, Alessio Menga, Valeria Poli, Paolo Ettore Porporato, Paolo Provero, Nadia Raffaelli, Chiara Riganti, Daniela Taverna, Federica Cavallo, Enzo Calautti
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-17 (2024)
Abstract Background The main drawback of BRAF/MEK inhibitors (BRAF/MEKi)-based targeted therapy in the management of BRAF-mutated cutaneous metastatic melanoma (MM) is the development of therapeutic resistance. We aimed to assess in this context the
Externí odkaz:
https://doaj.org/article/18874da7221f495c92ee85e23df7d535
Autor:
Antonella Rigo, Tiziana Vaisitti, Carlo Laudanna, Eleonora Terrabuio, Matilde Micillo, Cristina Frusteri, Beatrice D’Ulivo, Flavia Merigo, Andrea Sbarbati, Kevin Mellert, Peter Möeller, Alessio Montresor, Arianna Di Napoli, Roberto Cirombella, Elena Butturini, Massimo Massaia, Gabriela Constantin, Fabrizio Vinante, Silvia Deaglio, Isacco Ferrarini
Publikováno v:
Cell Death and Disease, Vol 15, Iss 5, Pp 1-15 (2024)
Abstract Richter’s syndrome (RS) is the transformation of chronic lymphocytic leukemia (CLL) into a high-grade B-cell malignancy. Molecular and functional studies have pointed out that CLL cells are close to the apoptotic threshold and dependent on
Externí odkaz:
https://doaj.org/article/611bace9a8024c29978a49892c3b1f93
Autor:
Angelo Corso Faini, Francesca Arruga, Michele Pinon, Valeria Bracciamà, Francesco Edoardo Vallone, Fiorenza Mioli, Monica Sorbini, Martina Migliorero, Alessandro Gambella, Damiano Carota, Isaac Giraudo, Paola Cassoni, Silvia Catalano, Renato Romagnoli, Antonio Amoroso, Pier Luigi Calvo, Tiziana Vaisitti, Silvia Deaglio
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 19, p 10483 (2024)
Hepatocellular adenomas (HAs) are tumors that can develop under different conditions, including in patients harboring a germline mutation in HNF1A. However, little is known about the pathogenesis of such disease. This work aims to better define what
Externí odkaz:
https://doaj.org/article/76c039fb1f534cec94aa4fcf365945eb
Autor:
Claudia Saglia, Valeria Bracciamà, Luca Trotta, Fiorenza Mioli, Angelo Corso Faini, Giulia Margherita Brach Del Prever, Silvia Kalantari, Maria Luca, Carmelo Maria Romeo, Caterina Scolari, Licia Peruzzi, Pier Luigi Calvo, Alessandro Mussa, Roberta Fenoglio, Dario Roccatello, Claudio Alberti, Diana Carli, Antonio Amoroso, Silvia Deaglio, Tiziana Vaisitti
Publikováno v:
BMC Medical Genomics, Vol 16, Iss 1, Pp 1-13 (2023)
Abstract Background In 2018, our center started a program to offer genetic diagnosis to patients with kidney and liver monogenic rare conditions, potentially eligible for organ transplantation. We exploited a clinical exome sequencing approach, follo
Externí odkaz:
https://doaj.org/article/1e7a2209db66432fa0f2f4bd0da27469
Autor:
Candida Vitale, Valentina Griggio, Maria Todaro, Chiara Riganti, Rebecca Jones, Elia Boccellato, Francesca Perutelli, Francesca Arruga, Tiziana Vaisitti, Dimitar G. Efremov, Silvia Deaglio, Yosef Landesman, Benedetto Bruno, Marta Coscia
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Despite recent relevant therapeutic progresses, chronic lymphocytic leukemia (CLL) remains an incurable disease. Selinexor, an oral inhibitor of the nuclear export protein XPO1, is active as single agent in different hematologic malignancies
Externí odkaz:
https://doaj.org/article/9c2f6dcf66b5460ab64440b2e4a9be40
Publikováno v:
Biomolecules, Vol 14, Iss 4, p 498 (2024)
Circulating cell-free DNA (cfDNA) refers to small fragments of DNA molecules released after programmed cell death and necrosis in several body fluids such as blood, saliva, urine, and cerebrospinal fluid. The discovery of cfDNA has revolutionized the
Externí odkaz:
https://doaj.org/article/2305d6d0dcf24dfa8d179d037dfdad12
Autor:
Silvia Deaglio, Ingo Ringshausen
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/ca5a41c0c2384da2b9876383ae6633b3