Výsledky vyhledávání - "Silvester, Ponist"

Akademický článek

Rhodiola rosea L. Extract, a Known Adaptogen, Evaluated in Experimental Arthritis

Autor: Frantisek Drafi, Katarina Bauerova, Martin Chrastina, Mohsen Taghdisiesfejír, João Rocha, Rosa Direito, Maria Eduardo Figueira, Bruno Sepodes, Silvester Ponist

Publikováno v: Molecules, Vol 28, Iss 13, p 5053 (2023)

Rhodiola rosea L. extract (RSE) is mostly known for its adaptogen properties, but not for its antiarthritic activities, therefore monotherapy and combination with low-dose methotrexate (MTX) was studied. The collagen-induced arthritis (CIA) model was

Externí odkaz: https://doaj.org/article/e01cac21c8fd4425b5e49f05a98685d6

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Possibilities of microemulsion application in rectal administration of indomethacin

Autor: Miroslava Špaglová, V. Mikušová, Katarína Bauerová, Silvester Ponist, Martina Čierna, Mária Čuchorová

Publikováno v: European Pharmaceutical Journal, Vol 68, Iss 1, Pp 94-97 (2021)

Rectal administration is a suitable route of administration for drugs that are either very irritating to the intestine (e.g., indomethacin) or are more effective when the first-pass effect in the liver is circumvented. Microemulsions are a tool for t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c73c413878b297888f263f1a3b64f0d3
https://doaj.org/article/a462f43471604461b0e375f0e9850457

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Inflammation in the Pathogenesis of Rheumatoid Arthritis and in Experimental Arthritis: Evaluation of Combinations of Carnosic Acid and Extract ofRhodiola roseaL. with Methotrexate

Autor: Silvester Ponist, Katarína Bauerová, Katarina Pruzinska

Publikováno v: Inflammation in the 21st Century ISBN: 9781839686412

The host immune response generates the pro-inflammatory immune response as a protective measure against invading pathogens, allergens, and/or trauma. However, dysregulated and chronic inflammation may result in secondary damage to tissues and immune

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23d32c74cf6de587079c96e489ab0014
https://doi.org/10.5772/intechopen.99073

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Effects of Selected Non-biological and Biological Disease-Modifying Anti-rheumatic Drugs, and mRNA Vaccines on Mononuclear Phagocyte System

Autor: Katarína Bauerová, Bruno Sepodes, Frantisek Drafi, Silvester Ponist

Publikováno v: Comprehensive Pharmacology ISBN: 9780128208762
Reference Module in Biomedical Sciences

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6d2595d9d173e1eb9737216786249a82
https://doi.org/10.1016/b978-0-12-820472-6.00110-9

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Hyperbilirubinemia Maintained by Chronic Supplementation of Unconjugated Bilirubin Improves the Clinical Course of Experimental Autoimmune Arthritis

Autor: Pavel Babal, Silvester Ponist, Tomas Sykora, Pavol Janega, Monika Dvorakova, Frantisek Drafi, Katarína Bauerová, Kristina Mikus-Kuracinova

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 8662, p 8662 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 16

Rheumatoid arthritis (RA) is a chronic multisystem disease, therapy of which remains a challenge for basic research. The present work examined the effect of unconjugated bilirubin (UCB) administration in adjuvant-induced arthritis (AIA)—an experime

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::def5574dd1d86b60d5494e932ae82a64
https://www.mdpi.com/1422-0067/22/16/8662

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Study of Anti-Inflammatory Activity of Fatsiphloginum™ (Fatsia japonica) and a New Purified Triterpene-Rich Extract of Saponins (PS-551) in Experimental Model of Arthritis

Autor: Silvester Ponist, Lia Tsiklauri, L Slovák, Karol Svik, E Kemertelidze, Frantisek Drafi, Z Kemoklidze, M Chrastina, Katarína Bauerová

Publikováno v: Physiological Research. :S75-S85

In this study, two extracts from Fatsia japonica-Fatsiphloginum™ (extract of triterpene glycosides containing 45-50 % of fatsiosides (FS)) and purified triterpene-rich extract of saponins with code name PS-551 (PS) were administered in combination

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f10ca05790e49537398121ebc5926b3c
https://doi.org/10.33549/physiolres.934328

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Microemulsions as Solubilizers and Penetration Enhancers for Minoxidil Release from Gels

Autor: Miroslava Špaglová, Katarína Bauerová, Martina Čierna, Silvester Ponist, Mária Čuchorová

Publikováno v: Gels
Volume 7
Issue 1
Gels, Vol 7, Iss 26, p 26 (2021)

Micro- and nanoemulsions are potential drug solubilizers and penetration enhancers through the high surfactant/co-surfactant content. This study aimed to evaluate the influence of minoxidil (MXD) solubilized in the microemulsions (MEs) on drug releas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::089659d84b666045538929214fca042d
http://europepmc.org/articles/PMC7931056

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Modulation of methotrexate efficacy by green tea polyphenols in rat adjuvant arthritis

Autor: Ludmila Paskova, Idolo Tedesco, Katarína Bauerová, Karol Svik, František Bilka, Gian Luigi Russo, Concetta Gardi, Silvester Ponist, Lukas Slovak

Publikováno v: PharmaNutrition 14 (2020). doi:10.1016/j.phanu.2020.100228
info:cnr-pdr/source/autori:Ponist, Silvester; Gardi, Concetta; Paskova, Ludmila; Svik, Karol; Slovak, Lukas; Bilka, Frantisek; Tedesco, Idolo; Bauerova, Katarina; Russo, Gian Luigi/titolo:Modulation of methotrexate efficacy by green tea polyphenols in rat adjuvant arthritis/doi:10.1016%2Fj.phanu.2020.100228/rivista:PharmaNutrition/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume:14

Background Green tea catechins are widely employed as dietary supplements to restore the oxidative state in adjuvant-induced arthritic rats, a model for human rheumatoid arthritis. Methotrexate is the first line antirheumatic drug. The present study

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac741eeb46e1ed2d678a4465ecc33cc7
http://www.cnr.it/prodotto/i/448990

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A new insight into effects of a clinically proved combination of methotrexate and hydroxychloroquine

Autor: Lukas Slovak, Katarína Bauerová, Silvester Ponist, Radomír Nosáľ, Ľudmila Pašková, Viera Kuncirova, Viera Jančinová, Danica Mihalova

Publikováno v: Monatshefte für Chemie - Chemical Monthly. 149:961-967

Combination of methotrexate (MTX) with hydroxychloroquine (HCQ) is one of the most effective therapies used for treatment of rheumatoid arthritis. The aim of the study was to more complexly examine the effect of combination HCQ and MTX on disease pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1070a558f2ebe1e3a7327d72a77c3a5e
https://doi.org/10.1007/s00706-018-2178-y

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