The different natural estrogens promote endothelial healing through distinct cell targets

Autor: Morgane Davezac, Rana Zahreddine, Melissa Buscato, Natalia F. Smirnova, Chanaelle Febrissy, Henrik Laurell, Silveric Gilardi-Bresson, Marine Adlanmerini, Philippe Liere, Gilles Flouriot, Rachida Guennoun, Muriel Laffargue, Jean-Michel Foidart, Françoise Lenfant, Jean-François Arnal, Raphaël Métivier, Coralie Fontaine

Publikováno v: JCI Insight, Vol 8, Iss 5 (2023)

The main estrogen, 17β-estradiol (E2), exerts several beneficial vascular actions through estrogen receptor α (ERα) in endothelial cells. However, the impact of other natural estrogens such as estriol (E3) and estetrol (E4) on arteries remains poo

Externí odkaz: https://doaj.org/article/cee391bdb2374d7ba32e1f7c699de3f8

Pain sensing neurons promote tissue regeneration in adult mice

Autor: Anne Lorsignol, Gilles Mithieux, Christophe Guissard, Silveric Gilardi, Marine Silva, Lionel Moulédous, Elodie Labit, Louis Casteilla, Lise Rabiller, Luc Pénicaud, Cécile Dromard, Bruno P. Guiard

Publikováno v: NPJ Regenerative Medicine
npj Regenerative Medicine, Vol 6, Iss 1, Pp 1-9 (2021)
NPJ Regenerative medicine
NPJ Regenerative medicine, 2021, 6 (1), pp.63. ⟨10.1038/s41536-021-00175-7⟩

Tissue repair after injury in adult mammals, usually results in scarring and loss of function in contrast to lower vertebrates such as the newt and zebrafish that regenerate. Understanding the regulatory processes that guide the outcome of tissue rep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::992b97c27810b83b392270600dbc9710
https://pubmed.ncbi.nlm.nih.gov/34650070