Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Silvanus Alt"'
Autor:
Liyuan Sui, Silvanus Alt, Martin Weigert, Natalie Dye, Suzanne Eaton, Florian Jug, Eugene W. Myers, Frank Jülicher, Guillaume Salbreux, Christian Dahmann
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Epithelial folding has mainly been linked to forces acting in the apical actomyosin network of cells. Here, the authors show using live imaging that two distinct mechanisms, changes in basal surface tension and changes in lateral surface tension, dri
Externí odkaz:
https://doaj.org/article/929bd8b435e7468db3d212a065345745
Autor:
Filipa Neto, Alexandra Klaus-Bergmann, Yu Ting Ong, Silvanus Alt, Anne-Clémence Vion, Anna Szymborska, Joana R Carvalho, Irene Hollfinger, Eireen Bartels-Klein, Claudio A Franco, Michael Potente, Holger Gerhardt
Publikováno v:
eLife, Vol 7 (2018)
Formation of blood vessel networks by sprouting angiogenesis is critical for tissue growth, homeostasis and regeneration. How endothelial cells arise in adequate numbers and arrange suitably to shape functional vascular networks is poorly understood.
Externí odkaz:
https://doaj.org/article/b2e688ced8914f49a847a12fffdbab93
Autor:
Wolfgang Giese, Andre Rosa, Elisabeth Baumann, Olya Oppenheim, Emir Bora Akmeric, Santiago Andrade, Irene Hollfinger, Silvanus Alt, Holger Gerhardt
Emerging concepts of developmental vascular remodelling recently identified that selectively labelled sprouting tip cells and/or venous endothelial cells (ECs) accumulate in developing arteries, suggesting directional migration of specific ECs drive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e8754ddc2ede898fb7c497d4ecf7377
https://doi.org/10.1101/2023.05.30.542799
https://doi.org/10.1101/2023.05.30.542799
Autor:
Rute M. M. Ferreira, Axel Behrens, Corina Cotoi, Hendrik A. Messal, Silvanus Alt, Christopher Gribben, Victoria M.-Y. Wang, Guillaume Salbreux
Publikováno v:
Messal, H A, Alt, S, Ferreira, R M M, Gribben, C, Wang, V M Y, Cotoi, C G, Salbreux, G & Behrens, A 2019, ' Tissue curvature and apicobasal mechanical tension imbalance instruct cancer morphogenesis ', Nature, vol. 566, no. 7742, pp. 126-130 . https://doi.org/10.1038/s41586-019-0891-2
Tubular epithelia are a basic building block of organs and a common site of cancer occurrence1–4. During tumorigenesis, transformed cells overproliferate and epithelial architecture is disrupted. However, the biophysical parameters that underlie th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e453d4d98f0a8648235e0acaeb94d76
https://doi.org/10.1038/s41586-019-0891-2
https://doi.org/10.1038/s41586-019-0891-2
Autor:
Katja Meier, A. Symborska-Mell, Eireen Bartels-Klein, Silvanus Alt, Russell T. Collins, Andre Rosa, Holger Gerhardt, Lowell T. Edgar, Miguel O. Bernabeu, Wolfgang Giese, Alexandra Klaus-Bergmann, Baptiste Coxam
Publikováno v:
Rosa, A, Giese, W, Meier, K, Alt, S, Klaus-Bergmann, A, Edgar, L T, Bartels, E, Collins, R, Szymborska, A, Coxam, B, Bernabeu, M O & Gerhardt, H 2021, ' Wasp controls oriented migration of endothelial cells to achieve functional vascular patterning ', Development . https://doi.org/10.1242/dev.200195
Endothelial cell migration and proliferation are essential for the establishment of a hierarchical organization of blood vessels and optimal distribution of blood. However, how these cellular processes are coordinated remains unknown. Here, using the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53fee427e4cd9418cb1f4139d0e06430
https://doi.org/10.2139/ssrn.3713451
https://doi.org/10.2139/ssrn.3713451
Autor:
Silvanus Alt, Martin Weigert, Liyuan Sui, Guillaume Salbreux, Eugene W. Myers, Natalie A. Dye, Christian Dahmann, Florian Jug, Suzanne Eaton, Frank Jülicher
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Nature Communications
Nature Communications
Epithelial folding transforms simple sheets of cells into complex three-dimensional tissues and organs during animal development. Epithelial folding has mainly been attributed to mechanical forces generated by an apically localized actomyosin network
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::948b71eb2116ab0320fbfcd4bbc94fe6
https://doaj.org/article/929bd8b435e7468db3d212a065345745
https://doaj.org/article/929bd8b435e7468db3d212a065345745
Autor:
Ilse Geudens, Véronique Gebala, Baptiste Coxam, Katja Meier, Anne-Clémence Vion, Andre Rosa, Silvanus Alt, Holger Gerhardt
Publikováno v:
Development (Cambridge, England)
Development (Cambridge, England), Company of Biologists, 2019, ⟨10.1242/dev.181024⟩
Development (Cambridge, England), Company of Biologists, 2019, ⟨10.1242/dev.181024⟩
How developing vascular networks acquire the right balance of arteries, veins and lymphatic vessels to efficiently supply and drain tissues is poorly understood. In zebrafish embryos, the robust and regular 50:50 global balance of intersegmental vein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47c7b990a05e46895e4af8b787535241
http://europepmc.org/articles/PMC6737902
http://europepmc.org/articles/PMC6737902
Autor:
Holger Gerhardt, Gebala, Silvanus Alt, Andre Rosa, Baptiste Coxam, Anne-Clémence Vion, Ilse Geudens
How developing vascular networks acquire the right balance of arteries, veins and lymphatics to efficiently supply and drain tissues is poorly understood [1, 2]. In zebrafish embryos, the robust and regular 50:50 global balance of intersegmental vein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5942ae25b0b6eb2496149b11d7808a06
Autor:
Barry J. Thompson, Maria-del-Carmen Diaz-de-la-Loza, Nic Tapon, Guillaume Salbreux, Robert P. Ray, Silvanus Alt, Andreas Hoppe, John Robert Davis, Poulami Somanya Ganguly
Publikováno v:
Developmental Cell
Summary Epithelial tissues can elongate in two dimensions by polarized cell intercalation, oriented cell division, or cell shape change, owing to local or global actomyosin contractile forces acting in the plane of the tissue. In addition, epithelia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8db64941f87f86193769779b2988d1dc
https://eprints.kingston.ac.uk/id/eprint/41418/1/Hoppe-A-41418-VoR.pdf
https://eprints.kingston.ac.uk/id/eprint/41418/1/Hoppe-A-41418-VoR.pdf
Autor:
Anne-Clémence Vion, Holger Gerhardt, Adel Hammoutene, Eireen Bartels-Klein, Miguel O. Bernabeu, Tijana Perovic, Anna Szymborska, Alexandra Klaus-Bergmann, Pierre-Emmanuel Rautou, Tuyu Zheng, Marta Bastos Oliveira, Silvanus Alt, Irene Hollfinger
Publikováno v:
Journal of Cell Biology
Journal of Cell Biology, Rockefeller University Press, 2018, 217 (5), pp.1651-1665. ⟨10.1083/jcb.201706151⟩
Vion, A-C, Alt, S, Klaus-Bergmann, A, Szymborska, A, Zheng, T, Perovic, T, Hammoutene, A, Oliveira, M B, Bartels-Klein, E, Hollfinger, I, Rautou, P-E, Bernabeu, M O & Gerhardt, H 2018, ' Primary cilia sensitize endothelial cells to BMP and prevent excessive vascular regression ', Journal of Cell Biology, vol. 217, no. 5, pp. 1651–1665 . https://doi.org/10.1083/jcb.201706151
The Journal of Cell Biology
Journal of Cell Biology, Rockefeller University Press, 2018, 217 (5), pp.1651-1665. ⟨10.1083/jcb.201706151⟩
Vion, A-C, Alt, S, Klaus-Bergmann, A, Szymborska, A, Zheng, T, Perovic, T, Hammoutene, A, Oliveira, M B, Bartels-Klein, E, Hollfinger, I, Rautou, P-E, Bernabeu, M O & Gerhardt, H 2018, ' Primary cilia sensitize endothelial cells to BMP and prevent excessive vascular regression ', Journal of Cell Biology, vol. 217, no. 5, pp. 1651–1665 . https://doi.org/10.1083/jcb.201706151
The Journal of Cell Biology
How endothelial cells sense and react to flow during vascular remodeling is poorly understood. Vion et al. show that endothelial cells utilize their primary cilia to stabilize vessel connections during vascular remodeling. Molecularly, they identify
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c73f222d5e7ec06494e274dd30d9324
http://hal.univ-nantes.fr/hal-03366493
http://hal.univ-nantes.fr/hal-03366493