Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Silvano Ronzoni"'
Autor:
Adolfo Prandi, Luca Ferrante, Maria Veneziano, Mariana Gallo, Marco Ferrara, Leda Ivanova Bencheva, Antonella Cellucci, Nausicaa Mazzocchi, Pierfausto Seneci, Silvano Ronzoni, Andrea Menegon, Roberta Sinisi, Pietro Randazzo, Vincenzo Summa, Marilenia De Matteo, Romano Di Fabio
[Image: see text] Acid-sensing ion channels (ASICs) are a family of ion channels permeable to cations and largely responsible for the onset of acid-evoked ion currents both in neurons and in different types of cancer cells, thus representing a potent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c8a3bad6284485d88304e25bccd2e07
http://hdl.handle.net/11588/828238
http://hdl.handle.net/11588/828238
Publikováno v:
Expert Opinion on Therapeutic Patents. 11:525-546
The discovery of the opioid receptor like-1 (ORL-1) receptor and of its endogenous agonist nociceptin/orphanin FQ has attracted great interest in the scientific community giving rise, in the last five years, to a flurry of biological studies aimed at
Autor:
Alberto Cerri, Silvano Ronzoni, Giovanni Fronza, Raveglia Luca Francesco, Giulio Dondio, Paola Petrillo, Pier Andrea Gatti
Publikováno v:
Organic Letters. 1:513-516
[formula: see text] Synthesis of four novel thieno derivatives 4-7 featuring the codeine skeletal backbone is reported. Characterization by 1H and 13C NMR is also discussed, along with binding profile for opioid receptors.
Publikováno v:
Expert Opinion on Therapeutic Patents. 9:353-374
A continuing effort in the development of non-peptide δ opioid agonists and antagonists has been seen in the last two years. The first non-peptide δ opioid antagonist naltrindole has represented for years the starting point for the design of novel
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 7:2967-2972
Structure Activity Relationship and docking studies focused on the role of the non-aromatic ° address in a novel class of potent and selective ° ligands, pyrrolooctahydroisoquinolines, are discussed.
Publikováno v:
Expert Opinion on Therapeutic Patents. 7:1075-1098
Following a flurry of medicinal chemistry activity in the late 1980s, a number of non-peptide pharmacological tools, selective for the δ opioid receptors, became available to challenge the pre-eminent position occupied by the existing peptide δ lig
Autor:
Geoffrey D. Clarke, Silvano Ronzoni, Carlo Farina, Paola Petrillo, Marco Artico, Drake S. Eggleston, Giulio Dondio, Giuseppe Petrone, Luciano Visentin, Vittorio Vecchietti
Publikováno v:
Journal of Medicinal Chemistry. 40:3192-3198
This paper describes the design and synthesis of compounds belonging to a novel class of substituted pyrrolooctahydroisoquinolines which are potent and selective delta opioid agonists. Molecular modeling studies performed on known, selective delta li
Autor:
Giulio Dondio, Luciano Visentin, Giardina Giuseppe Arnaldo Mari, Silvano Ronzoni, Geoffrey D. Clarke, Paola Petrillo, Giuseppe Petrone, Vittorio Vecchietti
Publikováno v:
Analgesia. 1:394-399
Publikováno v:
ChemInform. 29