Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Silvano Gobbo"'
Autor:
Giuseppe Tognon, Justina Šileikytė, Silvano Gobbo, Giulio Jori, Paolo Bernardi, Valeria Petronilli, Peter Nikolov, Fernanda Ricchelli, Alessandra Zulian, Federica Dabbeni-Sala
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1787(7):897-904
We have studied the mitochondrial permeability transition pore (PTP) under oxidizing conditions with mitochondria-bound hematoporphyrin, which generates reactive oxygen species (mainly singlet oxygen, 1O2) upon UV/visible light-irradiation and promot
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 37:1858-1868
It is well known that a lag phase generally elapses between the addition of inducers of the mitochondrial permeability transition and the opening of the pore. To advance our present understanding as regards the significance of this phenomenon, we use
Autor:
Adriana Visonà, Annalisa Angelini, Silvano Gobbo, Gaetano Thiene, Giulio Jori, Diego Tonello, Andrea Bonanome, Antonio Pagnan, Elena Bonandini
Publikováno v:
Journal of Photochemistry and Photobiology B: Biology. 57:94-101
Photodynamic therapy (PDT) appears to be a novel promising modality to prevent intimal hyperplasia (IH) and restenosis after angioplasty. Local PDT, that consists of local delivery of photosensitizing agents followed by intraluminal local irradiation
Publikováno v:
Biochemistry. 38:9295-9300
The dynamic properties of protein and lipid regions of mitochondrial membranes during the permeability transition (PT) process were studied by following the anisotropy changes of hematoporphyrin (HP) and 1,6-diphenyl-1,3,5-hexatriene (DPH), respectiv
Publikováno v:
European Journal of Biochemistry. 233:159-164
The temperature dependence of hematoporphyrin and protoporphyrin fluorescence quantum yields (phi F) was studied after delivery to whole mitochondria or isolated inner (IMM) and outer (OMM) mitochondrial membranes, obtained from liver of Wistar rats.
Autor:
Silvano Gobbo, Fernanda Ricchelli
Publikováno v:
Journal of Photochemistry and Photobiology B: Biology. 29:65-70
The distribution properties of haematoporphyrin (HP) and protoporphyrin (PP) (concentration range 0.5–15 μM) in small unilamellar vesicles (SUVs) of dimiristoylphosphatidylcholine (DMPC), sometimes mixed with cholesterol (Chol) or cardiolipin (Car
Autor:
Giulio Jori, Fernanda Ricchelli, Giuliana Moreno, Silvano Gobbo, Françoise Vinzens, Christian Salet
Publikováno v:
Photochemistry and Photobiology. 58:53-58
We have compared the photodynamic activities of hematoporphyrin (HP) and protoporphyrin (PP) on isolated rat liver mitochondria by measuring the decline of the respiratory control ratio (RCR) after irradiation at 365 nm. Before addition to the respir
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1065:42-48
Unilamellar liposomes of dipalmitoylphosphatidylcholine (DPPC) have been chosen as suitable models of cell membranes in studies aimed at defining the influence of specific parameters on the distribution properties of selected hydrophobic photosensiti
Autor:
Valeria, Petronilli, Justina, Sileikyte, Alessandra, Zulian, Federica, Dabbeni-Sala, Giulio, Jori, Silvano, Gobbo, Giuseppe, Tognon, Peter, Nikolov, Paolo, Bernardi, Fernanda, Ricchelli
Publikováno v:
Biochimica et biophysica acta. 1787(7)
We have studied the mitochondrial permeability transition pore (PTP) under oxidizing conditions with mitochondria-bound hematoporphyrin, which generates reactive oxygen species (mainly singlet oxygen, (1)O(2)) upon UV/visible light-irradiation and pr
Autor:
Jerry C. Bommer, Lisa Franchi, Giovanni Miotto, Fernanda Ricchelli, Elena Reddi, Silvano Gobbo, Lara Borsetto, Peter Nikolov
Publikováno v:
International journal of biochemistry & cell biology 37 (2005): 306–319. doi:10.1016/j.biocel.2004.06.013
info:cnr-pdr/source/autori:Ricchelli, F.; Franchi, L.; Miotto, G; Borsetto, L.; Gobbo, S.; Nikolov, P.; Bommer, J. C.; Reddi, E./titolo:Meso-substituted tetra-cationic porphyrins photosensitize the death of human fibrosarcoma cells via lysosomal targeting./doi:10.1016%2Fj.biocel.2004.06.013/rivista:International journal of biochemistry & cell biology/anno:2005/pagina_da:306/pagina_a:319/intervallo_pagine:306–319/volume:37
info:cnr-pdr/source/autori:Ricchelli, F.; Franchi, L.; Miotto, G; Borsetto, L.; Gobbo, S.; Nikolov, P.; Bommer, J. C.; Reddi, E./titolo:Meso-substituted tetra-cationic porphyrins photosensitize the death of human fibrosarcoma cells via lysosomal targeting./doi:10.1016%2Fj.biocel.2004.06.013/rivista:International journal of biochemistry & cell biology/anno:2005/pagina_da:306/pagina_a:319/intervallo_pagine:306–319/volume:37
In this paper we present a study on the intracellular localisation and the efficiency of cell photoinactivation of a series of derivatives of 5,10,15,20-tetrakis-(4-N-methylpyridyl)-porphine (C1), whose degree of lipophilicity was varied through repl