Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Silvana Sandri"'
Autor:
Pablo Scharf, Silvana Sandri, Felipe Rizzetto, Luana Filippi Xavier, Daniela Grosso, Rebeca D. Correia-Silva, Pedro S. Farsky, Cristiane D. Gil, Sandra Helena Poliselli Farsky
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionG-protein coupled receptors (GPCRs) expressed on neutrophils regulate their mobilization from the bone marrow into the blood, their half-live in the circulation, and their pro- and anti-inflammatory activities during inflammation. Chronic
Externí odkaz:
https://doaj.org/article/5edfdded248342dca59b426ce59b6330
Autor:
Cristina Bichels Hebeda, Anna Carolina Savioli, Pablo Scharf, Marina de Paula-Silva, Cristiane Damas Gil, Sandra Helena Poliselli Farsky, Silvana Sandri
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Maternal neutrophils cells are players in gestational tolerance and fetus delivery. Nonetheless, their actions in each phase of the pregnancy are unknown. We here investigated the role of maternal neutrophil depletion before the blastocyst implantati
Externí odkaz:
https://doaj.org/article/661d09eaa11f45ca905c2675da0dd902
Autor:
Silvana Sandri, Cristina Bichels Hebeda, Milena Fronza Broering, Marina de Paula Silva, Luciana Facure Moredo, Milton José de Barros e Silva, André Sapata Molina, Clóvis Antônio Lopes Pinto, João Pedreira Duprat Neto, Chris P. Reutelingsperger, Cristiane Damas Gil, Sandra Helena Poliselli Farsky
Publikováno v:
Cells, Vol 12, Iss 3, p 425 (2023)
Annexin A1 (AnxA1) is highly secreted by neutrophils and binds to formyl peptide receptors (FPRs) to trigger anti-inflammatory effects and efferocytosis. AnxA1 is also expressed in the tumor microenvironment, being mainly attributed to cancer cells.
Externí odkaz:
https://doaj.org/article/8c0fc4ca602d42638af809e85a9cfa23
Autor:
Marina de Paula-Silva, Gustavo Henrique Oliveira da Rocha, Milena Fronza Broering, Maria Luíza Queiroz, Silvana Sandri, Rodrigo Azevedo Loiola, Sonia Maria Oliani, Andrea Vieira, Mauro Perretti, Sandra Helena Poliselli Farsky
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Non-responsiveness to anti-TNF-α therapies presents relevant rates in inflammatory bowel disease patients, presenting the need to find biomarkers involved in therapeutic efficacy. Herein, we demonstrate that higher levels of colonic formyl peptide r
Externí odkaz:
https://doaj.org/article/c70005d39fa940c9a3d21cd717ae0035
Autor:
Edson Mendes de Oliveira, Jacqueline C. Silva, Thais P. Ascar, Silvana Sandri, Alexandre F. Marchi, Silene Migliorini, Helder T. I. Nakaya, Ricardo A. Fock, Ana Campa
Publikováno v:
Pharmaceutics, Vol 14, Iss 3, p 623 (2022)
In the course of infection and intense endotoxemia processes, induction of a catabolic state leading to weight loss is observed in mice and humans. However, the late effects of acute inflammation on energy homeostasis, regulation of body weight and g
Externí odkaz:
https://doaj.org/article/61dc056dc0994a20993a1c0dd5dd0eda
Autor:
Janesly Prates, Jusciéle Brogin Moreli, Alexandre Dantas Gimenes, Joice Matos Biselli, Solange Correa Garcia Pires D’Avila, Silvana Sandri, Sandra Helena Poliselli Farsky, Flávia Cristina Rodrigues-Lisoni, Sonia Maria Oliani
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 129, Iss , Pp 110331- (2020)
Cisplatin (Cis) is a choice chemotherapy approach to cervical cancer by inducing DNA adducts and subsequent apoptosis. We have investigated the effects of Cis on Annexin A1 (ANXA1) and inhibitor of DNA binding 1 (ID1) proteins expression to elucidate
Externí odkaz:
https://doaj.org/article/c20a1e4711a8429eab9e56bf1def1d6f
Autor:
Cristina B. Hebeda, Silvana Sandri, Cláudia M. Benis, Marina de Paula-Silva, Rodrigo A. Loiola, Chris Reutelingsperger, Mauro Perretti, Sandra H. P. Farsky
Publikováno v:
Cells, Vol 9, Iss 5, p 1188 (2020)
Embryo implantation into the uterine wall is a highly modulated, complex process. We previously demonstrated that Annexin A1 (AnxA1), which is a protein secreted by epithelial and inflammatory cells in the uterine microenvironment, controls embryo im
Externí odkaz:
https://doaj.org/article/7aaf098a691d4cf4bb407e22d197d61d
Autor:
Marcia Rodrigues da Silva, Adriana Schapochnik, Mayara Peres Leal, Janete Esteves, Cristina Bichels Hebeda, Silvana Sandri, Christiane Pavani, Anna Carolina Ratto Tempestini Horliana, Sandra H P Farsky, Adriana Lino-Dos-Santos-Franco
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0205535 (2018)
Paraquat (PQ) is one of the most widely employed herbicides that is used worldwide and it causes severe toxic effects in humans and animals. A PQ exposition can lead to pulmonary fibrosis (PF) and the mechanisms seem to be linked to oxidative stress,
Externí odkaz:
https://doaj.org/article/82de831c5faa444db012cbef14384d94
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 106, Iss 8, Pp 986-992 (2011)
In this study, we evaluated whether human serum and lipoproteins, especially high-density lipoprotein (HDL), affected serum amyloid A (SAA)-induced cytokine release. We verified the effects of SAA on THP-1 cells in serum-free medium compared to mediu
Externí odkaz:
https://doaj.org/article/b403de21c3284813aca53b820770ebc6
Autor:
Silvana Sandri, Alexandre Urban Borbely, Isabella Fernandes, Edson Mendes de Oliveira, Franciele Hinterholz Knebel, Rodrigo Ruano, Marcelo Zugaib, Fabiola Filippin-Monteiro, Estela Bevilacqua, Ana Campa
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90881 (2014)
The serum amyloid A (SAA) protein is known to function in the acute phase response and immunoregulation. Recently, SAA has been shown to be involved in cell proliferation, differentiation and migratory behavior in different cell types. Here, we evalu
Externí odkaz:
https://doaj.org/article/3863c6923e294ed1b00975e92acf0019