Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Silvana Caristi"'
Autor:
Martina Kunkl, Carola Amormino, Francesco Spallotta, Silvana Caristi, Maria Teresa Fiorillo, Alessandro Paiardini, Raymond Kaempfer, Loretta Tuosto
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/7398ad673f554322845e852eaafa09cc
Autor:
Martina Kunkl, Carola Amormino, Francesco Spallotta, Silvana Caristi, Maria Teresa Fiorillo, Alessandro Paiardini, Raymond Kaempfer, Loretta Tuosto
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Staphylococcus aureus superantigens (SAgs) such as staphylococcal enterotoxin A (SEA) and B (SEB) are potent toxins stimulating T cells to produce high levels of inflammatory cytokines, thus causing toxic shock and sepsis. Here we used a recently rel
Externí odkaz:
https://doaj.org/article/d0e37fe1b08242fb8f783f034f5b376d
Autor:
Martina Kunkl, Carola Amormino, Silvana Caristi, Valentina Tedeschi, Maria Teresa Fiorillo, Revital Levy, Andrey Popugailo, Raymond Kaempfer, Loretta Tuosto
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The inflammatory activity of staphylococcal enterotoxin B (SEB) relies on its capacity to trigger polyclonal T-cell activation by binding both T-cell receptor (TCR) and costimulatory receptor CD28 on T cells and MHC class II and B7 molecules on antig
Externí odkaz:
https://doaj.org/article/e9839b2de1114e4c8aeff04c20fb8389
Autor:
Benedetta Mattorre, Silvana Caristi, Simona Donato, Emilia Volpe, Marika Faiella, Alessandro Paiardini, Rosa Sorrentino, Fabiana Paladini
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 9, p 4961 (2022)
The M1 zinc metalloproteases ERAP1, ERAP2, and IRAP play a role in HLA-I antigen presentation by refining the peptidome either in the ER (ERAP1 and ERAP2) or in the endosomes (IRAP). They have also been entrusted with other, although less defined, fu
Externí odkaz:
https://doaj.org/article/fd73f7e18fa24775a19e9c957d64b09b
Autor:
Martina Kunkl, Carola Amormino, Simone Frascolla, Manolo Sambucci, Marco De Bardi, Silvana Caristi, Stefano Arcieri, Luca Battistini, Loretta Tuosto
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
IL-22 is a member of the IL-10 cytokine family involved in host protection against extracellular pathogens, by promoting epithelial cell regeneration and barrier functions. Dysregulation of IL-22 production has also frequently been observed in acute
Externí odkaz:
https://doaj.org/article/3c72d1847cc14192adef0935aa7355d7
Autor:
Nicla Porciello, Paola Grazioli, Antonio F. Campese, Martina Kunkl, Silvana Caristi, Marta Mastrogiovanni, Michela Muscolini, Francesca Spadaro, Cédric Favre, Jacques A. Nunès, Aldo Borroto, Balbino Alarcon, Isabella Screpanti, Loretta Tuosto
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
CD28 transmits co-stimulatory signals for the activation of both mouse and human T cells, but in vivo hyperactivation of CD28 has opposite effects on system immunity. Here, the authors show that a single amino acid difference between mouse and human
Externí odkaz:
https://doaj.org/article/e98ff31ccbfc47539c572574b4d9cb31
Autor:
Martina Kunkl, Marta Mastrogiovanni, Nicla Porciello, Silvana Caristi, Emanuele Monteleone, Stefano Arcieri, Loretta Tuosto
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
CD28 is an important co-stimulatory receptor for T lymphocytes that, in humans, delivers TCR-independent signal leading to the up-regulation of pro-inflammatory cytokines. We have recently reported that CD28 autonomous signaling induces the expressio
Externí odkaz:
https://doaj.org/article/65434f7d7a0f4cc3a07027357435ae21
Forkhead transcription factor FOXP3 upregulates CD25 expression through cooperation with RelA/NF-κB.
Autor:
Cristina Camperio, Silvana Caristi, Giorgia Fanelli, Marzia Soligo, Paola Del Porto, Enza Piccolella
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e48303 (2012)
Considerable evidence supports the prediction that CD25 is directly regulated by the forkhead transcription factor FOXP3. However, given that CD25 is normally upregulated in activated T cells, regardless of whether they express FOXP3, this issue has
Externí odkaz:
https://doaj.org/article/cce13a57d32443578a4e6bbe4542237f
Autor:
Elisa Nurzia, Daniele Narzi, Alberto Cauli, Alessandro Mathieu, Valentina Tedeschi, Silvana Caristi, Rosa Sorrentino, Rainer A Böckmann, Maria Teresa Fiorillo
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e32865 (2012)
The single amino acid replacement Asp116His distinguishes the two subtypes HLA-B*2705 and HLA-B*2709 which are, respectively, associated and non-associated with Ankylosing Spondylitis, an autoimmune chronic inflammatory disease. The reason for this d
Externí odkaz:
https://doaj.org/article/747b5cb091cb42f4830fc439f58b3f0b
Autor:
Benedetta Mattorre, Silvana Caristi, Simona Donato, Emilia Volpe, Marika Faiella, Alessandro Paiardini, Rosa Sorrentino, Fabiana Paladini
The M1 zinc metalloproteases ERAP1, ERAP2 and IRAP play a role in HLA-I antigen presentation by refining the peptidome either in the ER (ERAP1 and ERAP2) or in the endosomes (IRAP). They have been also entrusted with other, although less defined, fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2c7e78d74685f49c77d44cc6461304e
https://doi.org/10.1101/2022.03.07.483178
https://doi.org/10.1101/2022.03.07.483178