Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Silva Krause"'
Autor:
Justin Werfel, Silva Krause, Ashley G Bischof, Robert J Mannix, Heather Tobin, Yaneer Bar-Yam, Robert M Bellin, Donald E Ingber
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76122 (2013)
Changes in extracellular matrix (ECM) structure or mechanics can actively drive cancer progression; however, the underlying mechanism remains unknown. Here we explore whether this process could be mediated by changes in cell shape that lead to increa
Externí odkaz:
https://doaj.org/article/9f06e57e54424523ac945a502435ac64
Autor:
Silva Krause, Birgit C. Schultes, Martijn Lolkema, Kristen Getchell, Lynn Zhang, Edward Cochran, Chia Lin Chu, Ilse Oosterom, Victor Farutin, Jamey Guess, Jennifer Curran, Michelle Priess, Amanda MacDonald
Supplemental Figure 1 shows Pancreatic stellate cells (PSCs) promoted tumor cell invasion through close cell-cell interactions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a4cbed710fde6fff70072057c1d0653
https://doi.org/10.1158/1535-7163.22509292
https://doi.org/10.1158/1535-7163.22509292
Autor:
Silva Krause, Birgit C. Schultes, Martijn Lolkema, Kristen Getchell, Lynn Zhang, Edward Cochran, Chia Lin Chu, Ilse Oosterom, Victor Farutin, Jamey Guess, Jennifer Curran, Michelle Priess, Amanda MacDonald
Pancreatic cancer has an abysmal 5-year survival rate of 8%, making it a deadly disease with a need for novel therapies. Here we describe a multitargeting heparin-based mimetic, necuparanib, and its antitumor activity in both in vitro and in vivo mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d5af03daeb08cd8f057e5e131a81272
https://doi.org/10.1158/1535-7163.c.6539254.v1
https://doi.org/10.1158/1535-7163.c.6539254.v1
Autor:
Silva Krause, Birgit C. Schultes, Martijn Lolkema, Kristen Getchell, Lynn Zhang, Edward Cochran, Chia Lin Chu, Ilse Oosterom, Victor Farutin, Jamey Guess, Jennifer Curran, Michelle Priess, Amanda MacDonald
Supplementary Table 2 lists GO Categories significantly altered by necuparanib treatment, assigned to cancer-driving pathways
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa672d8d03409d99736c788d68c731b1
https://doi.org/10.1158/1535-7163.22509280.v1
https://doi.org/10.1158/1535-7163.22509280.v1
Autor:
Silva Krause, Birgit C. Schultes, Martijn Lolkema, Kristen Getchell, Lynn Zhang, Edward Cochran, Chia Lin Chu, Ilse Oosterom, Victor Farutin, Jamey Guess, Jennifer Curran, Michelle Priess, Amanda MacDonald
Supplementary Table 1 lists proteins significantly altered by necuparanib treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::469dfb91aebaa9a183ede9f1d24c2324
https://doi.org/10.1158/1535-7163.22509283.v1
https://doi.org/10.1158/1535-7163.22509283.v1
Autor:
Silva Krause, Birgit C. Schultes, Martijn Lolkema, Kristen Getchell, Lynn Zhang, Edward Cochran, Chia Lin Chu, Ilse Oosterom, Victor Farutin, Jamey Guess, Jennifer Curran, Michelle Priess, Amanda MacDonald
Supplemental Figure 3 shows MMP1 and MMP7 protein levels were unchanged in the plasma of patients.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0277567698a63467fb5213df82962200
https://doi.org/10.1158/1535-7163.22509286
https://doi.org/10.1158/1535-7163.22509286
Autor:
Silva Krause, Birgit C. Schultes, Martijn Lolkema, Kristen Getchell, Lynn Zhang, Edward Cochran, Chia Lin Chu, Ilse Oosterom, Victor Farutin, Jamey Guess, Jennifer Curran, Michelle Priess, Amanda MacDonald
Supplemental Figure 2 shows GM6001 reduced spheroid growth and invasion in the 3D co-culture model.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8304bfec79e0b08c9389f544bdfd17eb
https://doi.org/10.1158/1535-7163.22509289
https://doi.org/10.1158/1535-7163.22509289
Publikováno v:
Novas tecnologias e propriedades clínicas em odontologia 2 ISBN: 9786525807256
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b395f420540b9d5fda641072965274bf
https://doi.org/10.22533/at.ed.2562211114
https://doi.org/10.22533/at.ed.2562211114
Autor:
Melissa Hartmann, Doralúcia Gil da Silva, Juliane Portella Ribeiro, Cristiane da Silva Krause, Karen Barcelos Lopes
Publikováno v:
Revista Extensão em Ação. 20:105-117
O puerpério é um período que suscita cuidados, pois a mulher encontra-se fragilizada física e emocionalmente. Tal situação ganha contornos especiais quando o puerpério se desenvolve dentro do ambiente hospitalar, devido à hospitalização do
Autor:
David P. Ryan, Eileen M. O'Reilly, Kenneth H. Yu, James M. Roach, Donald A. Richards, Spencer H. Shao, Julie Wolf, Tanios Bekaii-Saab, Diletta Barone, Keith T. Flaherty, Devalingam Mahalingam, Molly Rosano, Silva Krause
Publikováno v:
Eur J Cancer
Background Necuparanib, a rationally engineered low-molecular-weight heparin, combined with gemcitabine/nab-paclitaxel showed an encouraging safety and oncologic signal in a phase Ib trial. This randomised multicentre phase II trial evaluates the add