Výsledky vyhledávání - "Silva H. Hanissian"

Jak3 Is Associated with CD40 and Is Critical for CD40 Induction of Gene Expression in B Cells

Publikováno v: Immunity. 6(4):379-387

CD40 is a receptor that is critical for the survival, growth, differentiation, and isotype switching of B lymphocytes. Although CD40 lacks intrinsic tyrosine kinase activity, its ligation induces protein tyrosine phosphorylation, which is necessary f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f228fc618cb1cf1333bbbd2cefb1a10

Zobrazit plný text záznamu

A Ca2+/calmodulin-dependent protein kinase, CaM kinase-Gr, expressed after transformation of primary human B lymphocytes by Epstein-Barr virus (EBV) is induced by the EBV oncogene LMP1

Autor: George Mosialos, Elliott Kieff, Talal A. Chatila, L. Vara, Satya Jawahar, Silva H. Hanissian

Publikováno v: Europe PubMed Central

CaM kinase-Gr is a multifunctional Ca2+/calmodulin-dependent protein kinase which is enriched in neurons and T lymphocytes. The kinase is absent from primary human B lymphocytes but is expressed in Epstein-Barr virus (EBV)-transformed B-lymphoblastoi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b6f2ab051359c638ccc383a88ccc01d
https://doi.org/10.1128/jvi.68.3.1697-1705.1994

Zobrazit plný text záznamu

Association of neuronal pp60c-src with growth cone glycoproteins of rat brain

Autor: Naji Sahyoun, Talal A. Chatila, Silva H. Hanissian

Publikováno v: Journal of Neurobiology. 23:803-813

Tyrosine phosphorylation and protein tyrosine kinase (PTK) activity in the growth cone membrane-associated glycoprotein (GCGP) fraction of 1-day-old rat brain were examined. Using immunoblotting and immunoprecipitation techniques, pp60c-src was ident

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::369821a00577b4260c8c82f624fc4ec5
https://doi.org/10.1002/neu.480230703

Zobrazit plný text záznamu

Regulation of myeloid leukemia factor-1 interacting protein (MLF1IP) expression in glioblastoma

Autor: Qihong Zhou, Umar Akbar, Silva H. Hanissian, Christopher Duntsch, Bin Teng, Jon H. Robertson, Zorica Janjetovic

Publikováno v: Brain research. 1047(1)

The myelodysplasia/myeloid leukemia factor 1-interacting protein MLF1IP is a novel gene which encodes for a putative transcriptional repressor. It is localized to human chromosome 4q35.1 and is expressed in both the nuclei and cytoplasm of cells. Nor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d137a679c2a4610c08ccc8e9382e8ef
https://pubmed.ncbi.nlm.nih.gov/15893739

Zobrazit plný text záznamu

Impaired synaptic plasticity and cAMP response element-binding protein activation in Ca2+/calmodulin-dependent protein kinase type IV/Gr-deficient mice

Autor: Lisa M. Muglia, Jason Liauw, David M. Holtzman, Feng Wei, Frank Blaeser, Silva H. Hanissian, Min Zhuo, A. Nardi, David F. Wozniak, David J. Linden, Nga Ho, Talal A. Chatila, Louis J. Muglia, Kara L. Arvin

Publikováno v: The Journal of neuroscience : the official journal of the Society for Neuroscience. 20(17)

The Ca(2+)/calmodulin-dependent protein kinase type IV/Gr (CaMKIV/Gr) is a key effector of neuronal Ca(2+) signaling; its function was analyzed by targeted gene disruption in mice. CaMKIV/Gr-deficient mice exhibited impaired neuronal cAMP-responsive

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::957cf08c96dfc3fd8f2c74dda4bf0c75
https://pubmed.ncbi.nlm.nih.gov/10964952

Zobrazit plný text záznamu

Ku in the cytoplasm associates with CD40 in human B cells and translocates into the nucleus following incubation with IL-4 and anti-CD40 mAb

Autor: Hirobumi Teraoka, Makoto Seki, Sang Kyou Lee, Silva H. Hanissian, Hiroyasu Nakano, Jun Kondo, Shigeaki Nonoyama, Raif S. Geha, Leonard B. Bacharier, Jun Ichi Yata, Tomohiro Morio

Publikováno v: Immunity. 11(3)

CD40 plays a critical role in survival, growth, differentiation, and class switching of B lymphocytes. Although Ku is required for immunoglobulin class switching, how CD40 signal transduction is coupled to Ku is still unknown. Here, we show that CD40

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91980bb8b876d66fad7d4a02959c667b
https://pubmed.ncbi.nlm.nih.gov/10514012

Zobrazit plný text záznamu

Homodimerization of the human interleukin 4 receptor alpha chain induces Cepsilon germline transcripts in B cells in the absence of the interleukin 2 receptor gamma chain

Autor: Alla V. Tsytsykova, Raif S. Geha, Hiroshi Fujiwara, Silva H. Hanissian

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America. 94(11)

The cytokines interleukin (IL)-4 and IL-13 play a critical role in inducing Cepsilon germline transcripts and IgE isotype switching in human B cells. The IL-4 receptor (IL-4R) in B cells is composed of two chains, the IL-4-binding IL-4Ralpha chain, w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1edcbcfdd29771a68a4d1471ada3898
https://pubmed.ncbi.nlm.nih.gov/9159166

Zobrazit plný text záznamu

Characterization of a 23-kDa protein associated with CD40

Autor: Tomohiro Morio, Raif S. Geha, Silva H. Hanissian

CD40 is a 45-kDa glycoprotein member of the tumor necrosis factor receptor (TNFR) family expressed on B cells, thymic epithelial cells, dendritic cells, and some carcinoma cells. The unique capacity of CD40 to trigger immunoglobulin isotype switching

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4da79352b8bc141480cceafef97f67c
https://europepmc.org/articles/PMC40456/

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání