Zobrazeno 1 - 10 of 16 pro vyhledávání: '"Silva H. Hanissian"'
1
cDNA cloning and characterization of a novel gene encoding the MLF1-interacting protein MLF1IP
Autor: Suraj Mukatira, Stephan W. Morris, Umar Akbar, Xiaoping Du, Silva H. Hanissian, Anne Hoffmann, Zorica Janjetovic, Norman N. Iscove, Johann Hitzler, Jon H. Robertson, Kristin M. Hamre, Bin Teng, Yiai Tong
Publikováno v: Oncogene. 23:3700-3707
Myelodysplasia/acute myeloid leukemia (MDS/AML) is characterized by a t(3;5)(q25.1;q34) chromosomal translocation that forms a fusion gene between nucleophosmin (NPM) and MDS/myeloid leukemia factor 1 (MLF1). We identified a novel protein, MLF1-inter
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5548e70026a676acf167d34755ff0a0d
https://doi.org/10.1038/sj.onc.1207448
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2
Jak3 Is Associated with CD40 and Is Critical for CD40 Induction of Gene Expression in B Cells
Autor: Silva H. Hanissian, Raif S. Geha
Publikováno v: Immunity. 6(4):379-387
CD40 is a receptor that is critical for the survival, growth, differentiation, and isotype switching of B lymphocytes. Although CD40 lacks intrinsic tyrosine kinase activity, its ligation induces protein tyrosine phosphorylation, which is necessary f
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f228fc618cb1cf1333bbbd2cefb1a10
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3
A Ca2+/calmodulin-dependent protein kinase, CaM kinase-Gr, expressed after transformation of primary human B lymphocytes by Epstein-Barr virus (EBV) is induced by the EBV oncogene LMP1
Autor: George Mosialos, Elliott Kieff, Talal A. Chatila, L. Vara, Satya Jawahar, Silva H. Hanissian
Publikováno v: Europe PubMed Central
CaM kinase-Gr is a multifunctional Ca2+/calmodulin-dependent protein kinase which is enriched in neurons and T lymphocytes. The kinase is absent from primary human B lymphocytes but is expressed in Epstein-Barr virus (EBV)-transformed B-lymphoblastoi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b6f2ab051359c638ccc383a88ccc01d
https://doi.org/10.1128/jvi.68.3.1697-1705.1994
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4
Association of neuronal pp60c-src with growth cone glycoproteins of rat brain
Autor: Naji Sahyoun, Talal A. Chatila, Silva H. Hanissian
Publikováno v: Journal of Neurobiology. 23:803-813
Tyrosine phosphorylation and protein tyrosine kinase (PTK) activity in the growth cone membrane-associated glycoprotein (GCGP) fraction of 1-day-old rat brain were examined. Using immunoblotting and immunoprecipitation techniques, pp60c-src was ident
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::369821a00577b4260c8c82f624fc4ec5
https://doi.org/10.1002/neu.480230703
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5
Regulation of myeloid leukemia factor-1 interacting protein (MLF1IP) expression in glioblastoma
Autor: Qihong Zhou, Umar Akbar, Silva H. Hanissian, Christopher Duntsch, Bin Teng, Jon H. Robertson, Zorica Janjetovic
Publikováno v: Brain research. 1047(1)
The myelodysplasia/myeloid leukemia factor 1-interacting protein MLF1IP is a novel gene which encodes for a putative transcriptional repressor. It is localized to human chromosome 4q35.1 and is expressed in both the nuclei and cytoplasm of cells. Nor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d137a679c2a4610c08ccc8e9382e8ef
https://pubmed.ncbi.nlm.nih.gov/15893739
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6
Impaired synaptic plasticity and cAMP response element-binding protein activation in Ca2+/calmodulin-dependent protein kinase type IV/Gr-deficient mice
Autor: Lisa M. Muglia, Jason Liauw, David M. Holtzman, Feng Wei, Frank Blaeser, Silva H. Hanissian, Min Zhuo, A. Nardi, David F. Wozniak, David J. Linden, Nga Ho, Talal A. Chatila, Louis J. Muglia, Kara L. Arvin
Publikováno v: The Journal of neuroscience : the official journal of the Society for Neuroscience. 20(17)
The Ca(2+)/calmodulin-dependent protein kinase type IV/Gr (CaMKIV/Gr) is a key effector of neuronal Ca(2+) signaling; its function was analyzed by targeted gene disruption in mice. CaMKIV/Gr-deficient mice exhibited impaired neuronal cAMP-responsive
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::957cf08c96dfc3fd8f2c74dda4bf0c75
https://pubmed.ncbi.nlm.nih.gov/10964952
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7
Ku in the cytoplasm associates with CD40 in human B cells and translocates into the nucleus following incubation with IL-4 and anti-CD40 mAb
Autor: Hirobumi Teraoka, Makoto Seki, Sang Kyou Lee, Silva H. Hanissian, Hiroyasu Nakano, Jun Kondo, Shigeaki Nonoyama, Raif S. Geha, Leonard B. Bacharier, Jun Ichi Yata, Tomohiro Morio
Publikováno v: Immunity. 11(3)
CD40 plays a critical role in survival, growth, differentiation, and class switching of B lymphocytes. Although Ku is required for immunoglobulin class switching, how CD40 signal transduction is coupled to Ku is still unknown. Here, we show that CD40
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91980bb8b876d66fad7d4a02959c667b
https://pubmed.ncbi.nlm.nih.gov/10514012
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8
Homodimerization of the human interleukin 4 receptor alpha chain induces Cepsilon germline transcripts in B cells in the absence of the interleukin 2 receptor gamma chain
Autor: Alla V. Tsytsykova, Raif S. Geha, Hiroshi Fujiwara, Silva H. Hanissian
Publikováno v: Proceedings of the National Academy of Sciences of the United States of America. 94(11)
The cytokines interleukin (IL)-4 and IL-13 play a critical role in inducing Cepsilon germline transcripts and IgE isotype switching in human B cells. The IL-4 receptor (IL-4R) in B cells is composed of two chains, the IL-4-binding IL-4Ralpha chain, w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1edcbcfdd29771a68a4d1471ada3898
https://pubmed.ncbi.nlm.nih.gov/9159166
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