Antibacterial Profile in vitro and in vivo of New 1,4-Naphthoquinones Tethered to 1,2,3-1H-Triazoles Against the Planktonic Growth of Streptococcus mutans

Autor: Gomes,Mônica P., Correia,Eduardo M., Gomes,Max W. L., Santos,Claudio C. C. dos, Barros,Caroline S., Abreu,Fernanda V. de, Antunes,Leonardo S., Ferreira,Vitor F., Gonçalves,Mariana C., Resende,Gabriel O. de, Gonzaga,Daniel T. G., Pinto,Carla E. C., Paixão,Izabel C. N. P., Silva,Fernando C. da

Publikováno v: Journal of the Brazilian Chemical Society, Volume: 33, Issue: 9, Pages: 1028-1040, Published: 26 AUG 2022
Journal of the Brazilian Chemical Society v.33 n.9 2022
Journal of the Brazilian Chemical Society
Sociedade Brasileira de Química (SBQ)
instacron:SBQ

The cariogenic processes are mainly caused by the bacterium Streptococcus mutans (S. mutans) and consist of the demineralization of the tooth that occurs when the acid production overcomes the natural repair or if a problem occurs in the last one. In

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::59e0ff8872b210a1f0605a0ff1452427
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532022000901028&lng=en&tlng=en

Synthesis and Anti-Chikungunya Virus (CHIKV) Activity of Novel 1,4-Naphthoquinone Sulfonamide and Sulfonate Ester Derivatives

Autor: Pacheco,Paulo A. F., Gonzaga,Daniel T., Cirne-Santos,Cláudio C., Barros,Caroline S., Gomes,Max W. L., Gomes,Rafaela S. P., Gonçalves,Mariana C., Ferreira,Vitor F., Rabelo,Vitor W., Abreu,Paula A., Faria,Robson X., Resende,Gabriel O. de, Rocha,David R. da, Paixão,Izabel C. N. P., Silva,Fernando C. da

Publikováno v: Journal of the Brazilian Chemical Society, Volume: 33, Issue: 6, Pages: 556-569, Published: 30 MAY 2022
Journal of the Brazilian Chemical Society v.33 n.6 2022
Journal of the Brazilian Chemical Society
Sociedade Brasileira de Química (SBQ)
instacron:SBQ

Chikungunya virus (CHIKV) is a re-emerging disease caused by an alphavirus of the Togaviridae family. Since its first description in 1952, the disease has spread worldwide, affecting populations in both tropical and temperate countries. To date, ther

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::5a27b24685d5c53502be8bd2a4e407c6
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532022000600556&lng=en&tlng=en

Seleno- and Telluro-Functionalization of Quinones: Molecules with Relevant Biological Application

Autor: Cordeiro, Pâmella S., Chipoline, Ingrid C., Ribeiro, Ruan C. B., Pinho, David R., Ferreira, Vitor F., Silva, Fernando C. da, Forezi, Luana S. M., Nascimento, Vanessa

Publikováno v: Journal of the Brazilian Chemical Society v.33 n.2 2022
Journal of the Brazilian Chemical Society
Sociedade Brasileira de Química (SBQ)
instacron:SBQ
Journal of the Brazilian Chemical Society, Volume: 33, Issue: 2, Pages: 111-127, Published: 24 JAN 2022

Quinones and organochalcogens are classes of compounds with great biological applicability, such as antioxidant, anticancer, anti-Alzheimer, and antidepressant activities, among others. Thus, the combination of these two classes of compounds is impor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::bf0f466691f0074cb51840fc2413c95d
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532022000200111

New natural products from Siphoneugena densiflora Berg (Myrtaceae) and their chemotaxonomic significance

Autor: Gallo Margareth B. C., Silva Fernando C. da, Vieira Paulo C., Fernandes João B., Silva Maria Fátima das G. F. da

Publikováno v: Journal of the Brazilian Chemical Society, Vol 17, Iss 2, Pp 279-288 (2006)

Siphoneugena Berg (Myrtaceae) is a small eugenioid genus segregated from Eugenia by Berg. The phytochemical survey of Siphoneugena densiflora was carried out in order to find secondary metabolites which may be considered as chemotaxonomic characters

Externí odkaz: https://doaj.org/article/c89e89719ed04179a7ad1c7f2447115d

Inhibition of Zika Virus Replication by Synthetic Bis-Naphthoquinones

Autor: Gonzaga,Daniel T. G., Gomes,Rafaela S. P., Marra,Roberta K. F., Silva,Fernando C. da, Gomes,Max W. L., Ferreira,Davis F., Santos,Raissa M. A., Pinto,Ana M. V., Ratcliffe,Norman Arthur, Cirne-Santos,Claudio C., Barros,Caroline S., Ferreira,Vitor F., Paixão,Izabel Christina N. P.

Publikováno v: Journal of the Brazilian Chemical Society, Volume: 30, Issue: 8, Pages: 1697-1706, Published: 12 AUG 2019
Journal of the Brazilian Chemical Society v.30 n.8 2019
Journal of the Brazilian Chemical Society
Sociedade Brasileira de Química (SBQ)
instacron:SBQ

Zika virus (ZIKV) is a mosquito-borne pathogen which is a current global public health concern. There are currently no approved vaccines or antivirals against ZIKV infection. Taking into account that naphthoquinones have shown promising antiviral act

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::9f129c6e1dfc0d1cfe636e91443332db
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532019000801697&lng=en&tlng=en