Multiple Spectroscopic and Theoretical Approaches to Study the Interaction between HSA and the Antiparasitic Drugs: Benznidazole, Metronidazole, Nifurtimox and Megazol

Autor: Chaves, Otávio A., Ferreira, Romulo C., Silva, Lorrayne S. da, Souza, Bruna C. E. de, Cesarin-Sobrinho, Dari, Netto-Ferreira, José Carlos, Sant’Anna, Carlos M. R., Ferreira, Aurélio B. B.

Publikováno v: Journal of the Brazilian Chemical Society v.29 n.7 2018
Journal of the Brazilian Chemical Society
Sociedade Brasileira de Química (SBQ)
instacron:SBQ
Journal of the Brazilian Chemical Society, Volume: 29, Issue: 7, Pages: 1551-1562, Published: JUL 2018

The interaction between four antiparasitic drugs (benznidazole (BZL), metronidazole (MTZ), nifurtimox (NFX) and megazol (MZ)) with human serum albumin (HSA), the main vehicle of biodistribution of xenobiotics, hydrophobic, small and endogenous molecu

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