DENV-3 precursor membrane (prM) glycoprotein enhances E protein immunogenicity and confers protection against DENV-2 infections in a murine model.

Autor: Dias, Roberto S., Teixeira, Michelle D., Xisto, Mariana F., Prates, John W. O., Silva, Jessica D. Da, Mello, Iago O., Silva, Cynthia C. Da, De Paula, Sérgio O.

Publikováno v: Human Vaccines & Immunotherapeutics; 2021, Vol. 17 Issue 5, p1271-1277, 7p

NS3 and NS5 proteins: important targets for anti-dengue drug design

Autor: Oliveira, André S. de, Silva, Milene L. da, Oliveira, Ana Flávia C. S., Silva, Cynthia C. da, Teixeira, Róbson R., De Paula, Sérgio O.

Publikováno v: Journal of the Brazilian Chemical Society v.25 n.10 2014
Journal of the Brazilian Chemical Society
Sociedade Brasileira de Química (SBQ)
instacron:SBQ
Journal of the Brazilian Chemical Society, Volume: 25, Issue: 10, Pages: 1759-1769, Published: OCT 2014

Dengue is a neglected disease, one that is responsible for 22,000 deaths each year in areas where it is endemic. Despite the tremendous efforts invested in research for dengue treatments, no vaccine or antiviral has reached the market, and disease tr

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