Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Silmara Lúcia Grego Alves"'
Autor:
Gabriellen Menezes Migliani de Castro, Yasmin da Silva Fontes, Silmara Lúcia Grego Alves, Leandro Augusto Oliveira Barbosa, José Augusto Ferreira Perez Villar, Antonio Galina Filho, Sergio Henrique Seabra, Anna Lea Silva Barreto, Ana Claudia Tessis, Dirlei Nico, Antonio Ferreira-Pereira
Publikováno v:
Journal of Taibah University for Science, Vol 18, Iss 1 (2024)
Leishmania infantum is responsible for visceral leishmaniasis, the most severe form of the disease. The treatments currently used are pentavalent antimonials and amphotericin B, but they present serious side effects and resistant species that already
Externí odkaz:
https://doaj.org/article/173af655ea054b9e8062f82f12a14e4d
Autor:
Gisele Capanema, de Oliveira, Sayonarah Carvalho, Rocha, Miliane Alves, da Silva Lopes, Natasha, Paixão, Silmara Lúcia Grego, Alves, Marco Túlio Corrêa, Pessoa, François, Noël, Luis Eduardo M, Quintas, Leandro Augusto, Barbosa, José Augusto Ferreira Perez, Villar, Vanessa Faria, Cortes
Publikováno v:
The Journal of membrane biology. 254(5-6)
Na,K-ATPase (NKA) and cardiotonic steroids (CTS) have shown potent cytotoxic and anticancer effects. Here, we have synthesized a series of CTS digoxin derivatives (γ-benzylidene) with substitutions in the lactone ring and evaluated the cytotoxicity