Influenza A virus challenge models in Cynomolgus macaques using the authentic inhaled aerosol and intra-nasal routes of infection

Autor: Marriott, AC, Dennis, M, Kane, JA, Gooch, KE, Hatch, G, Sharpe, S, Prevosto, C, Leeming, G, Zekeng, E-G, Staples, KJ, Hall, G, Ryan, KA, Bate, S, Moyo, N, Whittaker, CJ, Hallis, B, Silman, NJ, Lalvani, A, Wilkinson, TM, Hiscox, JA, Stewart, JP, Carroll, MW, Pöhlmann, S

Publikováno v: PLoS ONE
PLoS ONE, Vol 11, Iss 6, p e0157887 (2016)
PLoS One

Non-human primates are the animals closest to humans for use in influenza A virus challenge studies, in terms of their phylogenetic relatedness, physiology and immune systems. Previous studies have shown that cynomolgus macaques (Macaca fascicularis)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2780db3c77cc82da2295462d22568a9a
http://ora.ox.ac.uk/objects/uuid:

Crystal structure of the essential transcription antiterminator M2-1 protein of human respiratory syncytial virus and implications of its phosphorylation

Autor: Tanner, SJ, Ariza, A, Richard, CA, Kyle, HF, Dods, RL, Blondot, ML, Wu, W, Trincão, J, Trinh, CH, Hiscox, JA, Carroll, MW, Silman, NJ, Eléouët, JF, Edwards, TA, Barr, JN

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2014, 111 (4), pp.1580-1585. ⟨10.1073/pnas.1317262111⟩

International audience; The M2-1 protein of the important pathogen human respiratory syncytial virus is a zinc-binding transcription antiterminator that is essential for viral gene expression. We present the crystal structure of full-length M2-1 prot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0aaa88bf7896b4d794b58214639cf432
https://hal.inrae.fr/hal-02631183

Cellular immune response to human influenza viruses differs between H1N1 and H3N2 subtypes in the ferret lung.

Autor: Ryan KA; National Infection Service, Public Health England, Porton Down, Wiltshire, United Kingdom., Slack GS; National Infection Service, Public Health England, Porton Down, Wiltshire, United Kingdom., Marriott AC; National Infection Service, Public Health England, Porton Down, Wiltshire, United Kingdom., Kane JA; National Infection Service, Public Health England, Porton Down, Wiltshire, United Kingdom., Whittaker CJ; National Infection Service, Public Health England, Porton Down, Wiltshire, United Kingdom., Silman NJ; National Infection Service, Public Health England, Porton Down, Wiltshire, United Kingdom., Carroll MW; National Infection Service, Public Health England, Porton Down, Wiltshire, United Kingdom., Gooch KE; National Infection Service, Public Health England, Porton Down, Wiltshire, United Kingdom.

Publikováno v: PloS one [PLoS One] 2018 Sep 07; Vol. 13 (9), pp. e0202675. Date of Electronic Publication: 2018 Sep 07 (Print Publication: 2018).

Case study: design and implementation of training for scientists deploying to Ebola diagnostic field laboratories in Sierra Leone: October 2014 to February 2016.

Autor: Logue CH; Novel and Dangerous Pathogens Training, Public Health England, Porton Down, Salisbury, Wiltshire, SP4 0JG, UK christopher.logue@phe.gov.uk., Lewis SM; Novel and Dangerous Pathogens Training, Public Health England, Porton Down, Salisbury, Wiltshire, SP4 0JG, UK., Lansley A; Novel and Dangerous Pathogens Training, Public Health England, Porton Down, Salisbury, Wiltshire, SP4 0JG, UK., Fraser S; Novel and Dangerous Pathogens Training, Public Health England, Porton Down, Salisbury, Wiltshire, SP4 0JG, UK., Shieber C; Novel and Dangerous Pathogens Training, Public Health England, Porton Down, Salisbury, Wiltshire, SP4 0JG, UK., Shah S; Novel and Dangerous Pathogens Training, Public Health England, Porton Down, Salisbury, Wiltshire, SP4 0JG, UK., Semper A; Novel and Dangerous Pathogens Training, Public Health England, Porton Down, Salisbury, Wiltshire, SP4 0JG, UK., Bailey D; Novel and Dangerous Pathogens Training, Public Health England, Porton Down, Salisbury, Wiltshire, SP4 0JG, UK., Busuttil J; Novel and Dangerous Pathogens Training, Public Health England, Porton Down, Salisbury, Wiltshire, SP4 0JG, UK., Evans L; Novel and Dangerous Pathogens Training, Public Health England, Porton Down, Salisbury, Wiltshire, SP4 0JG, UK., Carroll MW; Novel and Dangerous Pathogens Training, Public Health England, Porton Down, Salisbury, Wiltshire, SP4 0JG, UK., Silman NJ; Novel and Dangerous Pathogens Training, Public Health England, Porton Down, Salisbury, Wiltshire, SP4 0JG, UK., Brooks T; Novel and Dangerous Pathogens Training, Public Health England, Porton Down, Salisbury, Wiltshire, SP4 0JG, UK., Shallcross JA; Novel and Dangerous Pathogens Training, Public Health England, Porton Down, Salisbury, Wiltshire, SP4 0JG, UK.

Publikováno v: Philosophical transactions of the Royal Society of London. Series B, Biological sciences [Philos Trans R Soc Lond B Biol Sci] 2017 May 26; Vol. 372 (1721).

Molecular characterization of an outbreak-involved Bacillus anthracis strain confirms the spillover of anthrax from West Africa.

Autor: Wang, Shuchao¹ (AUTHOR), Suluku, Roland² (AUTHOR) rsuluku@njala.edu.sl, Jalloh, Mohamed B.³ (AUTHOR), Samba, Ahmed F.⁴ (AUTHOR), Jiang, Baogui⁵ (AUTHOR), Xie, Yubiao¹ (AUTHOR), Harding, Doris⁶ (AUTHOR), Zhang, Mengyao⁷ (AUTHOR), Sahr, Foday³ (AUTHOR), Sesay, Mahmud E.² (AUTHOR), Squire, James S.⁶ (AUTHOR), Vandi, Mohamed A.⁶ (AUTHOR), Kallon, Moinina N.² (AUTHOR), Zhang, Shoufeng¹ (AUTHOR), Hu, Rongliang¹ (AUTHOR), Zhao, Yuee⁵ (AUTHOR) zhaoyuee163@163.com, Mi, Zhiqiang⁵ (AUTHOR) zhiqiangmi_ime@163.com

Publikováno v: Infectious Diseases of Poverty. 1/15/2024, Vol. 13 Issue 1, p1-12. 12p.